Results 21 to 30 of about 10,900 (273)
Effects of digitoxin compared to placebo on efficacy and safety in patients with heart failure and reduced ejection fraction (HFrEF). Primary endpoint: time to all‐cause death and first hospitalization for worsening heart failure (whatever occurs first). ACEi, angiotensin‐converting enzyme inhibitor; ARB, angiotensin receptor blocker; ARNI, angiotensin
Udo Bavendiek+35 more
wiley +2 more sources
Digitalis Therapy Is Associated With an Increased Risk of ICD Shock Delivery and Device Revision. [PDF]
In the presence of more nonischemic cardiomyopathy and more comorbidities in the digoxin group, digitalis glycosides were associated with an increased risk for rehospitalization or device revision, while no significant differences in mortality or major complications, including stroke or myocardial infarction, were observed.
Frommeyer G+9 more
europepmc +2 more sources
While there are targeted treatments for triple positive breast cancers, lack of specific biomarkers for triple-negative breast cancers (TNBC) has hindered the development of therapies for this subset of cancers. In this study, we evaluated the anticancer
Yogesh M Kulkarni+6 more
doaj +2 more sources
Ex vivo activity of cardiac glycosides in acute leukaemia. [PDF]
BACKGROUND: Despite years of interest in the anti-cancerous effects of cardiac glycosides (CGs), and numerous studies in vitro and in animals, it has not yet been possible to utilize this potential clinically. Reports have demonstrated promising in vitro
Helene Hallböök+6 more
doaj +5 more sources
Exploring bacterial key genes and therapeutic agents for breast cancer among the Ghanaian female population: Insights from In Silico analyses. [PDF]
Breast cancer (BC) is yet a significant global health challenge across various populations including Ghana, though several studies on host-genome associated with BC have been investigated molecular mechanisms of BC development and progression, and ...
Md Kaderi Kibria+2 more
doaj +2 more sources
Inflammation in the COVID-19 airway is due to inhibition of CFTR signaling by the SARS-CoV-2 spike protein [PDF]
SARS-CoV-2-contributes to sickness and death in COVID-19 patients partly by inducing a hyper-proinflammatory immune response in the host airway. This hyper-proinflammatory state involves activation of signaling by NFκB, and unexpectedly, ENaC, the ...
Hung Caohuy+11 more
doaj +2 more sources
Der Nachweis von Digitoxin [PDF]
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R. H. Lavermann
openaire +5 more sources
Simple and safe digitoxin dosing in heart failure based on data from the DIGIT-HF trial. [PDF]
The present study aimed to develop a simple dosing score when starting the cardiac glycoside digitoxin in heart failure with reduced ejection fraction (HFrEF) employing first data from the randomized, double-blinded DIGIT-HF trial. In DIGIT-HF, digitoxin
Bavendiek U+23 more
europepmc +2 more sources
Ueber Digitoxin und Digitalin [PDF]
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H. Kiliani
openaire +3 more sources
Cardiac glycosides digoxin and digitoxin are used in therapy for the treatment of congestive heart failure. Moreover, these compounds can be responsible for intoxication cases caused by fortuitous ingestion of leaves of Digitalis.
Marco Ballotari+6 more
semanticscholar +1 more source