Results 41 to 50 of about 4,113 (206)
A clinical evaluation of acetyl-digitoxin
, 1956 The advantages of the pure glycosides are well known. A new cardiac glycoside like acetyl-digitoxin therefore merits careful evaluation. Stoll and Kreins,1 prepared acetyl-digitoxin from lanatoside A by enzymatic cleavage of one molecule of glucose.
John, Donald +4 more
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Ex vivo activity of cardiac glycosides in acute leukaemia. [PDF]
PLoS ONE, 2011 BACKGROUND: Despite years of interest in the anti-cancerous effects of cardiac glycosides (CGs), and numerous studies in vitro and in animals, it has not yet been possible to utilize this potential clinically. Reports have demonstrated promising in vitro
Helene Hallböök +6 more
doaj +1 more source
, 2016 A mild and atom-economic rhenium(V)-catalyzed stereoselective synthesis of β-d-digitoxosides from 6-deoxy-d-allals has been described. This β-selective glycosylation was achieved probably because of the formation of corresponding α-digitoxosides ...
Jianglong Zhu (1528864) +2 more
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Revista Colombiana de Biotecnología, 2014 Digitalis purpurea L. es una de las principales fuentes de cardenólidos tales como digoxina y digitoxina. Estos fármacos son ampliamente usados en la disfunción cardíaca y para regular las arritmias del corazón.
Naivy Lisbet Pérez-Alonso +6 more
doaj +1 more source
, 2022 The alpha subunits (ATP1A1-3) of Na(+)/K(+)-ATPase binds digitoxin with varying affinity. The expression levels of these subunits dictate the anticancer effects of digitoxin.
Lindholm, Heléne, +5 more
core +1 more source
Senolytics and exercise: Dual modalities for rejuvenating muscle
The Journal of Physiology, EarlyView.Abstract figure legend The role of senolytics on the heart and skeletal muscle. Senescent cell burden increases with ageing, disuse and disease. The senolytics dasatinib+quercetin (D+Q), navitoclax and fisetin, as well as exercise, eliminate senescent cells, reducing senescent cell burden and their senescence‐associated secretory phenotype (SASP ...
Zeynep Elif Yesilyurt‐Dirican +4 more
wiley +1 more source
Drug Repurposing Against SARS-CoV-2: Targeting NSP16-NSP10 Interaction
Journal of the Turkish Chemical Society, Section A: Chemistry, 2021 Drug repurposing studies played an important role for fighting with the Covid-19 pandemic. Discovering a new drug molecule for a disease takes a very long time. However, repurposing a drug molecule developed for another disease can accelerate to find new
Sefer BADAY
doaj +1 more source
Cardiac Glycosides in Human Physiology and Disease: Update for Entomologists
Insects, 2019 Cardiac glycosides, cardenolides and bufadienolides, are elaborated by several plant or animal species to prevent grazing or predation. Entomologists have characterized several insect species that have evolved the ability to sequester these glycosides in
Rif S. El-Mallakh +2 more
doaj +1 more source
eFood, Volume 7, Issue 4, August 2026.Antidesma montanum, an edible wild plant, shows notable nutraceutical and pharmacological potential. Methanol extract profiling (GC–MS) identified bioactive metabolites. In vitro, in vivo, and in silico studies demonstrated significant antidiabetic, anthelmintic, anxiolytic, antidepressant, and antidiarrheal activities, supported by strong molecular ...
Naureen Banu +9 more
wiley +1 more source
Intestinal absorption of digitoxin and its water-soluble metabolites in cats. [PDF]
Intestinal absorption of 3H-digitoxin and its water-soluble metabolites was studied in biliary fistula induced cats to elucidate the mechanism of the enterohepatic circulation of digitoxin.
吉田, 康彦
core +1 more source