Results 61 to 70 of about 3,061 (175)
Background Apixaban is commonly used in anticoagulation therapy. Its safety profile is associated with polypharmacy and potential drug–drug interactions (DDIs). Current understanding often focuses on canonical metabolic pathways, while other biological factors of haemorrhagic risk remain not fully described.
Zhuang Chen +3 more
wiley +1 more source
The Renaissance of Digitoxin Is Overdue [PDF]
A 12-page review article on heart failure is very commendable (1). However, it is a source of irritation that in such a comprehensive article, a total of six lines is all that is given to the positive inotropic digitalis glycosides. A distinction between digoxin and digitoxin was not provided. Positive experiences have been reported for a long time for
openaire +2 more sources
Repurposing cardiac glycosides (CGs) significantly strengthens the efficacy of anti‐CD47 antibody for lung cancer treatment by boosting macrophage phagocytosis. This novel combination blocks the “don't eat me” signal and increases dual “eat‐me” signals, Fc‐FcγR and cell surface expression of calreticulin (ecto‐CRT).
Zi‐Han Ye +9 more
wiley +1 more source
While there are targeted treatments for triple positive breast cancers, lack of specific biomarkers for triple-negative breast cancers (TNBC) has hindered the development of therapies for this subset of cancers. In this study, we evaluated the anticancer
Yogesh M Kulkarni +6 more
doaj +1 more source
Abstract Background Metastasis is the leading cause of cancer‐related mortality, with circulating tumor cell (CTC) clusters serving as highly efficient precursors of distant metastasis. Survival of CTC clusters in the bloodstream is the primary contributor to tumor metastasis.
Rui Tang +12 more
wiley +1 more source
Rasmus Rivinius,1 Matthias Helmschrott,1 Arjang Ruhparwar,2 Ann-Kathrin Rahm,1,3 Fabrice F Darche,1 Dierk Thomas,1 Tom Bruckner,4 Philipp Ehlermann,1 Hugo A Katus,1 Andreas O Doesch1,5 1Department of Cardiology, Angiology and Pneumology, Heidelberg ...
Rivinius R +9 more
doaj
The Therapeutic Effects of Digitoxine [PDF]
n ...
openaire +2 more sources
Multi-spectroscopic investigation of the binding interaction of fosfomycin with bovine serum albumin
The interaction between fosfomycin (FOS) and bovine serum albumin (BSA) has been investigated effectively by multi-spectroscopic techniques under physiological pH 7.4. FOS quenched the intrinsic fluorescence of BSA via static quenching.
Manjunath D. Meti +4 more
doaj +1 more source
CLINICAL NOTES ON DIGITOXIN. [PDF]
Among the few really indispensable drugs which we have, digitalis would be placed in the very front rank by most medical men, and this is true in spite of the fact that its use is attended by certain disadvantages, and that these disadvantages are not regularly to be estimated, owing to the complex nature of the constituents of the drug, and the ...
openaire +2 more sources
Bacopaside I is a triterpenoid saponin, a major compound in Bacopa monnieri , which exhibits several potentially useful clinical activities including memory enhancement.
Sontaya Sookying +4 more
doaj +1 more source

