Results 61 to 70 of about 3,061 (175)

Drug–Drug Interaction Signals for Apixaban‐Associated Haemorrhage in Atrial Fibrillation and Thromboembolic Disorders: A Disproportionality Analysis of the FAERS Database

open access: yesJournal of Interventional Cardiology, Volume 2026, Issue 1, 2026.
Background Apixaban is commonly used in anticoagulation therapy. Its safety profile is associated with polypharmacy and potential drug–drug interactions (DDIs). Current understanding often focuses on canonical metabolic pathways, while other biological factors of haemorrhagic risk remain not fully described.
Zhuang Chen   +3 more
wiley   +1 more source

The Renaissance of Digitoxin Is Overdue [PDF]

open access: yesDeutsches Ärzteblatt international, 2016
A 12-page review article on heart failure is very commendable (1). However, it is a source of irritation that in such a comprehensive article, a total of six lines is all that is given to the positive inotropic digitalis glycosides. A distinction between digoxin and digitoxin was not provided. Positive experiences have been reported for a long time for
openaire   +2 more sources

Repurposing Cardiac Glycosides to Potentiate CD47 Blockade through Calreticulin‐mediated Phagocytic Effects for Lung Cancer Treatment

open access: yesAdvanced Science, Volume 12, Issue 46, December 11, 2025.
Repurposing cardiac glycosides (CGs) significantly strengthens the efficacy of anti‐CD47 antibody for lung cancer treatment by boosting macrophage phagocytosis. This novel combination blocks the “don't eat me” signal and increases dual “eat‐me” signals, Fc‐FcγR and cell surface expression of calreticulin (ecto‐CRT).
Zi‐Han Ye   +9 more
wiley   +1 more source

Anti-tumorigenic effects of a novel digitoxin derivative on both estrogen receptor–positive and triple-negative breast cancer cells

open access: yesTumor Biology, 2017
While there are targeted treatments for triple positive breast cancers, lack of specific biomarkers for triple-negative breast cancers (TNBC) has hindered the development of therapies for this subset of cancers. In this study, we evaluated the anticancer
Yogesh M Kulkarni   +6 more
doaj   +1 more source

Unfolded protein response kinase PERK supports survival and metastasis of circulating tumor cell clusters via SAM synthesis and H3K4me3‐dependent PDGFB signaling

open access: yesCancer Communications, Volume 45, Issue 12, Page 1706-1733, December 2025.
Abstract Background Metastasis is the leading cause of cancer‐related mortality, with circulating tumor cell (CTC) clusters serving as highly efficient precursors of distant metastasis. Survival of CTC clusters in the bloodstream is the primary contributor to tumor metastasis.
Rui Tang   +12 more
wiley   +1 more source

Chronic digitalis therapy in patients before heart transplantation is an independent risk factor for increased posttransplant mortality

open access: yesTherapeutics and Clinical Risk Management, 2017
Rasmus Rivinius,1 Matthias Helmschrott,1 Arjang Ruhparwar,2 Ann-Kathrin Rahm,1,3 Fabrice F Darche,1 Dierk Thomas,1 Tom Bruckner,4 Philipp Ehlermann,1 Hugo A Katus,1 Andreas O Doesch1,5 1Department of Cardiology, Angiology and Pneumology, Heidelberg ...
Rivinius R   +9 more
doaj  

The Therapeutic Effects of Digitoxine [PDF]

open access: yesThe American Journal of the Medical Sciences, 1894
n ...
openaire   +2 more sources

Multi-spectroscopic investigation of the binding interaction of fosfomycin with bovine serum albumin

open access: yesJournal of Pharmaceutical Analysis, 2015
The interaction between fosfomycin (FOS) and bovine serum albumin (BSA) has been investigated effectively by multi-spectroscopic techniques under physiological pH 7.4. FOS quenched the intrinsic fluorescence of BSA via static quenching.
Manjunath D. Meti   +4 more
doaj   +1 more source

CLINICAL NOTES ON DIGITOXIN. [PDF]

open access: yesJAMA: The Journal of the American Medical Association, 1899
Among the few really indispensable drugs which we have, digitalis would be placed in the very front rank by most medical men, and this is true in spite of the fact that its use is attended by certain disadvantages, and that these disadvantages are not regularly to be estimated, owing to the complex nature of the constituents of the drug, and the ...
openaire   +2 more sources

Quantitation of Bacopaside I in Rat Biological Samples by LC-QTOF-MS/MS and Its Pharmacokinetic Application

open access: yesNatural Product Communications, 2017
Bacopaside I is a triterpenoid saponin, a major compound in Bacopa monnieri , which exhibits several potentially useful clinical activities including memory enhancement.
Sontaya Sookying   +4 more
doaj   +1 more source

Home - About - Disclaimer - Privacy