Results 61 to 70 of about 3,653 (213)
The antiangiogenic effect of digitoxin is dependent on a ROS-elicited RhoA/ROCK pathway activation [PDF]
We previously showed that digitoxin inhibits angiogenesis and cancer cell proliferation and migration and these effects were associated to protein tyrosine kinase 2 (FAK) inhibition.
Dal Maso, Lucia +6 more
core +1 more source
Production of cadiotonic glycosides in Digitalis purpurea using temporary immersion systems
Biotecnología Vegetal, 2005 Digitalis purpurea, is an example of cardiotonic drug. Digoxin and digitoxin are glycosides produced by this plant which are cardiac stimulants with a wide use in the treatment of heart problems.
Naivy Pérez-Alonso +6 more
doaj
Clinical Impact of Digitalis Therapy in a Large Multicenter Cohort of CRT-Recipients
Journal of Cardiovascular Development and Disease(1) Introduction: Digitalis use in patients with severe heart failure is controversial. We assessed the effects of digitalis therapy on mortality in a large, observational study in recipients of cardiac resynchronization therapy (CRT).
Julia W. Erath +7 more
doaj +1 more source
Intestinal absorption of digitoxin and its water-soluble metabolites in cats.
, 1974 Intestinal absorption of 3H-digitoxin and its water-soluble metabolites was studied in biliary fistula induced cats to elucidate the mechanism of the enterohepatic circulation of digitoxin.
吉田, 康彦
core +1 more source
OSWALD SCHMIEDEBERG –THE “FATHER” OF EXPERIMENTAL PHARMACOLOGY [PDF]
Research Results in Pharmacology, 2017 Biography. Oswald Schmiedeberg (1838-1921) was a son of a bailiff and a maid of honour, the eldest of the six children in the family. He was born and educated in the Russian Empire. Scientific activity. All his life he was completely devoted to science,
Mikhail Pokrovskii +3 more
doaj +3 more sources
European Journal of Inorganic Chemistry, Volume 29, Issue 1, January 1, 2026.Synthesis, photophysical and electrochemical characterization of tetra‐cationic porphyrins containing Re(I) complexes and BSA‐binding properties In this article, isomeric tetra‐cationic porphyrins with rhenium(I)‐carbonyl‐phenanthroline complexes at the peripheral N‐pyridyl positions 3ReP and 4ReP were evaluated for structural characterization ...
Rafaela C. Copello +8 more
wiley +1 more source
, 1979 In order to determine the mechanism of cumulative effect of digitalis, the author investigated the distribution of digitoxin in miscellaneous tissue of the cat at 1 and 48 hr after a single intravenous injection of 3H-digitoxin （20% of the standard ...
塚田, 英樹
core +1 more source
Melanoma: Pathogenesis and Targeted Therapy
MedComm, Volume 7, Issue 1, January 2026.The treatment landscape for advanced melanoma has evolved significantly. BRAF–MEK inhibitor combinations are standard for BRAF‐mutant melanoma, whereas targeting NRAS mutations is more challenging, with MEK inhibitors like tunlametinib emerging as an option.
Yang Fu +5 more
wiley +1 more source
Data in Brief, 2020 Cardiac glycosides, steroid derivatives extracted from the foxglove plants, have been used for the treatment of heart failure since the 18th century. A method based on liquid chromatography coupled with high-resolution tandem mass spectrometry (LC/MS2 ...
Baradwaj Gopal Ravi +3 more
doaj +1 more source