Results 51 to 60 of about 6,490 (199)

The mechanisms of Chansu in inducing efficient apoptosis in colon cancer cells [PDF]

, 2013
Chansu is one of the most widely used traditional Chinese medicines in China, Japan, and other Southeast Asian countries primarily for antipain, anti-inflammation, and recently anticancer.
Cao, Siyu, Duan, Wei, Good, David, Hashimi, Saeed M., Li, Chun, Mellick, Albert S., Wei, Ming Q.   +6 more
core   +3 more sources

Krisanaklan Reduces Intestinal Anion and Fluid Secretion Through Inhibition of Na+/K+‐ATPase and K+ Channel Activity

Annals of the New York Academy of Sciences, Volume 1556, Issue 1, February 2026.
Krisanaklan reduces CFTR‐dependent intestinal chloride and fluid secretion by inhibiting the Na+,K+‐ATPase and K+ channels in epithelial cells. Consequently, this natural, plant‐derived product may limit secretory diarrhea caused by a diverse array of microbial pathogens. However, by dissipating the transmembrane Na+ gradient, Krisanaklan also inhibits
Tessa A. Groeneweg, Erdene Baigal, Anny Leung, Gert‐Jan Kremers, Marcel J. C. Bijvelds   +4 more
wiley   +1 more source

Employment of artificial intelligence approach for optimizing the solubility of drug in the supercritical CO2 system

Case Studies in Thermal Engineering
This paper investigates the solubility behavior of digitoxin in supercritical carbon dioxide (CO2) through a comprehensive analysis employing ensemble learning techniques and various regression models.
Meixiuli Li, Wenyan Jiang, Shuang Zhao, Kai Huang, Dongxiu Liu   +4 more
doaj   +1 more source

Investigation of Relationship Between Chemical Stress Factors and Certain Metabolites Including Cardenolides in Callus Cultures of Endemic Turkish Digitalis L. Species

International Journal of Secondary Metabolite, 2017
The aim of the present research is to obtain relationship between different stress treatments [Cu (copper) and Hg (mercury)] and content of cardiac glycosides (digoxigenin, gitoxigenin, lanatoside C, digoxin and digitoxin) as secondary metabolites of ...
Gunce Sahin, Sandeep Kumar Verma, Ekrem Gurel   +2 more
doaj   +1 more source

Implementation of Research and Development Based on Patent Natural Ingredients and Potential Utilization of Tradition Medicine [PDF]

, 2016
. The results of research and development based on natural ingredients for traditional medicines become an interesting topic to discuss at this point; it's shown from increasing number in utilization. The use of traditional medicine especially on natural
Hendrix, T. (Tommy)
core   +2 more sources

Peruvoside, a Cardiac Glycoside, Induces Primitive Myeloid Leukemia Cell Death

Molecules, 2016
Despite the available chemotherapy and treatment, leukemia remains a difficult disease to cure due to frequent relapses after treatment. Among the heterogeneous leukemic cells, a rare population referred as the leukemic stem cell (LSC), is thought to be ...
Qian Feng, Wa Seng Leong, Liang Liu, Wai-In Chan   +3 more
doaj   +1 more source

Combined amiodarone and digitalis therapy before heart transplantation is associated with increased post‐transplant mortality

ESC Heart Failure, 2020
Aims Amiodarone and digitalis are frequently used drugs in patients with heart failure. Both have separately been linked to reduced post‐transplant survival, but their combined impact on mortality after HTX remains uncertain.
Rasmus Rivinius, Matthias Helmschrott, Ann‐Kathrin Rahm, Fabrice F. Darche, Dierk Thomas, Tom Bruckner, Andreas O. Doesch, Philipp Ehlermann, Hugo A. Katus, Edgar Zitron   +9 more
doaj   +1 more source

In vitro and in vivo antileishmanial activity of β-acetyl-digitoxin, a cardenolide of Digitalis lanata potentially useful to treat visceral leishmaniasis

Parasite, 2021
Current treatments of visceral leishmaniasis face limitations due to drug side effects and/or high cost, along with the emergence of parasite resistance. Novel and low-cost antileishmanial agents are therefore required.
Freitas Camila S., Lage Daniela P., Oliveira-da-Silva João A., Costa Rafaella R., Mendonça Débora V.C., Martins Vívian T., Reis Thiago A.R., Antinarelli Luciana M.R., Machado Amanda S., Tavares Grasiele S.V., Ramos Fernanda F., Brito Rory C.F., Ludolf Fernanda, Chávez-Fumagalli Miguel A., Roatt Bruno M., Ramos Gabriela S., Munkert Jennifer, Ottoni Flaviano M., Campana Priscilla R.V., Duarte Mariana C., Gonçalves Denise U., Coimbra Elaine S., Braga Fernão C., Pádua Rodrigo M., Coelho Eduardo A.F.   +24 more
doaj   +1 more source

Older patients' prescriptions screening in the community pharmacy: development of the Ghent Older People's Prescriptions community Pharmacy Screening (GheOP3S) tool [PDF]

, 2015
Background: Ageing of the population often leads to polypharmacy. Consequently, potentially inappropriate prescribing (PIP) becomes more frequent. Systematic screening for PIP in older patients in primary care could yield a large improvement in health ...
Boussery, Koen, Mehuys, Els, Petrovic, Mirko, Somers, Annemie, Tommelein, Eline, van der Cammen, Tischa   +5 more
core   +2 more sources

Tetra‐Cationic Pyridyl‐Porphyrins With Peripheral Rhenium(I) Complexes: Photophysics, Photobiological, and BSA‐Binding Properties

European Journal of Inorganic Chemistry, Volume 29, Issue 1, January 1, 2026.
Synthesis, photophysical and electrochemical characterization of tetra‐cationic porphyrins containing Re(I) complexes and BSA‐binding properties In this article, isomeric tetra‐cationic porphyrins with rhenium(I)‐carbonyl‐phenanthroline complexes at the peripheral N‐pyridyl positions 3ReP and 4ReP were evaluated for structural characterization ...
Rafaela C. Copello, André S. Polo, Rafael de Q. Garcia, Leonardo De Boni, Luiz Antônio Sodré Costa, Henrique F. V. Victória, Klaus Krambrock, Otávio A. Chaves, Bernardo A. Iglesias   +8 more
wiley   +1 more source