Results 71 to 80 of about 4,113 (206)

Cytotoxic effects of digitoxin.

, 2013
A: Cytotoxic effects of digitoxin (0.1 µM) expressed as Survival Index % (vs. untreated control cells) in the various leukaemia types (T-ALL, B precursor ALL, AML and CLL) and PBMC using the standard 72 h assay.
Lars Bohlin (358023), Rolf Larsson (73378), Helene Hallböök (358020), Mårten Fryknäs (72946), Anna Eriksson (176834), Jenny Felth (358021), Joachim Gullbo (358025)   +6 more
core   +1 more source

Production of cadiotonic glycosides in Digitalis purpurea using temporary immersion systems

Biotecnología Vegetal, 2005
Digitalis purpurea, is an example of cardiotonic drug. Digoxin and digitoxin are glycosides produced by this plant which are cardiac stimulants with a wide use in the treatment of heart problems.
Naivy Pérez-Alonso, Elio Jiménez, Dirk Wilken, André Gerth, Annett Jähn, Horst-Michael Nitzsche, Gerhard Kerns   +6 more
doaj  

Clinical Impact of Digitalis Therapy in a Large Multicenter Cohort of CRT-Recipients

Journal of Cardiovascular Development and Disease
(1) Introduction: Digitalis use in patients with severe heart failure is controversial. We assessed the effects of digitalis therapy on mortality in a large, observational study in recipients of cardiac resynchronization therapy (CRT).
Julia W. Erath, Nikolett Vigh, Balazs Muk, Carsten W. Israel, Sarah Keck, David Pilecky, Gabor Z. Duray, Mate Vamos   +7 more
doaj   +1 more source

Combined amiodarone and digitalis therapy before heart transplantation is associated with increased post‐transplant mortality

ESC Heart Failure, 2020
Aims Amiodarone and digitalis are frequently used drugs in patients with heart failure. Both have separately been linked to reduced post‐transplant survival, but their combined impact on mortality after HTX remains uncertain.
Rasmus Rivinius, Matthias Helmschrott, Ann‐Kathrin Rahm, Fabrice F. Darche, Dierk Thomas, Tom Bruckner, Andreas O. Doesch, Philipp Ehlermann, Hugo A. Katus, Edgar Zitron   +9 more
doaj   +1 more source

Evolutionary constraints in host shifts: Limited adaptation of Plutella xylostella to cardenolide‐defended Erysimum cheiranthoides

Functional Ecology, Volume 40, Issue 2, Page 501-516, February 2026.
Read the free Plain Language Summary for this article on the Journal blog. Abstract Coevolutionary arms races between plants and insects, in which gains of novel plant defences select for counteradaptations in herbivores, are key drivers of biodiversity.
Broti Biswas, Erik van Bergen, Teresa Vaello, Laura J. Dällenbach, Christopher W. Wheat, Tobias Züst   +5 more
wiley   +1 more source

Krisanaklan Reduces Intestinal Anion and Fluid Secretion Through Inhibition of Na+/K+‐ATPase and K+ Channel Activity

Annals of the New York Academy of Sciences, Volume 1556, Issue 1, February 2026.
Krisanaklan reduces CFTR‐dependent intestinal chloride and fluid secretion by inhibiting the Na+,K+‐ATPase and K+ channels in epithelial cells. Consequently, this natural, plant‐derived product may limit secretory diarrhea caused by a diverse array of microbial pathogens. However, by dissipating the transmembrane Na+ gradient, Krisanaklan also inhibits
Tessa A. Groeneweg, Erdene Baigal, Anny Leung, Gert‐Jan Kremers, Marcel J. C. Bijvelds   +4 more
wiley   +1 more source

The antiangiogenic effect of digitoxin is dependent on a ROS-elicited RhoA/ROCK pathway activation [PDF]

We previously showed that digitoxin inhibits angiogenesis and cancer cell proliferation and migration and these effects were associated to protein tyrosine kinase 2 (FAK) inhibition.
Dal Maso, Lucia, Schimdt, Gudula, Bolego, Chiara, Trevisi, Lucia, Schmidt, Gudula, Cignarella, Andrea, Boscaro, Carlotta   +6 more
core   +1 more source

Ueber β‐Digitoxin [PDF]

Archiv der Pharmazie, 1895
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openaire   +2 more sources

Clinical Implementation of Pharmacogenomics and Drug–Drug Interaction Screening in a German Academic Teaching Hospital and Outpatient Follow‐Up

Clinical Pharmacology &Therapeutics, Volume 119, Issue 1, Page 241-254, January 2026.
Overview of the implemented pharmacogenomics (PGx) process in clinical routine at the Robert Bosch Hospital: from patient enrollment via the hospital information system, DNA detection using a customized TaqMan OpenArray panel and qPCR for CNV assessment, to clinical translation of genotyping results into PGx guideline‐based recommendations using a ...
Roman Tremmel, Filippa Schreeck, Simon Jaeger, Severin Schricker, Elke Schaeffeler, Svitlana Igel, Daniela Steinberger, Manuel Pagitz, Jörg Latus, Markus Ketteler, Kerstin Bühl, Marc‐H. Dahlke, Hans‐Georg Kopp, Matthias Schwab   +13 more
wiley   +1 more source

Tetra‐Cationic Pyridyl‐Porphyrins With Peripheral Rhenium(I) Complexes: Photophysics, Photobiological, and BSA‐Binding Properties

European Journal of Inorganic Chemistry, Volume 29, Issue 1, January 1, 2026.
Synthesis, photophysical and electrochemical characterization of tetra‐cationic porphyrins containing Re(I) complexes and BSA‐binding properties In this article, isomeric tetra‐cationic porphyrins with rhenium(I)‐carbonyl‐phenanthroline complexes at the peripheral N‐pyridyl positions 3ReP and 4ReP were evaluated for structural characterization ...
Rafaela C. Copello, André S. Polo, Rafael de Q. Garcia, Leonardo De Boni, Luiz Antônio Sodré Costa, Henrique F. V. Victória, Klaus Krambrock, Otávio A. Chaves, Bernardo A. Iglesias   +8 more
wiley   +1 more source