Results 91 to 100 of about 3,653 (213)

腎臓のDigitoxin捕捉に関する研究

, 1954
The isolated kidney of guinea pig was perfused with blood containing digitoxin, and the digitoxin uptake of kidney was determined by assaing the potency of perfusion fluid and overflow using guinea pigs.
筒井, 高紀
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Digitoxinの作用に及ぼす血液の影響について

, 1954
Experiments were carried out with guinea pigs concerning influences of blood on the lethal dose of digitoxin which was determined by intravenous injection of 0.01% digitoxin solution.
松家, 利男, 筒井, 高紀, 南雲, 猛, 田邊, 恒義   +3 more
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CLINICAL NOTES ON DIGITOXIN. [PDF]

JAMA: The Journal of the American Medical Association, 1899
Among the few really indispensable drugs which we have, digitalis would be placed in the very front rank by most medical men, and this is true in spite of the fact that its use is attended by certain disadvantages, and that these disadvantages are not regularly to be estimated, owing to the complex nature of the constituents of the drug, and the ...
openaire   +2 more sources

Formation of Tumorspheres with Increased Stemness without External Mitogens in a Lung Cancer Model

Stem Cells International, 2016
Like with most solid tumors, the presence of a subpopulation of cancer stem cells (CSCs) or cancer stem-like cells (CS-LCs) has been associated with chemoresistance and tumor relapse in lung cancer cells.
Juan Sebastian Yakisich, Neelam Azad, Rajkumar Venkatadri, Yogesh Kulkarni, Clayton Wright, Vivek Kaushik, Anand Krishnan V. Iyer   +6 more
doaj   +1 more source

Biotransformation of Digitoxin by Aspergillus Ochraceus

, 2011
Biotransformations of natural products have great potential for preparation of lead compounds. In this paper, the biotransformation of digitoxin (1) with Aspergillus ochraceus afforded two products, identified as digitoxigenin (2) and sarmentogenin (3 ...
Yan Jun Shen, Yu Wan Fu, Min Wang, Xi Chen, Hua Sun   +4 more
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Synthesis, anticancer properties, and biological profiling of synthetic glycan analogs of proscillaridin A

Discover Pharmaceutical Sciences
Several cardiac glycosides, including digoxin, digitoxin, and proscillaridin A, have been originally identified as cardiomyocyte modulators and are currently being investigated for their anticancer properties.
Shreya Somani, Lekhya Menta, Feng Wang-Johanning, Gary Johanning, Seoyeon Hong, Edward Njoo   +5 more
doaj   +1 more source

Digitoxin Prolongs Survival of Female Rats With Heart Failure Due to Large Myocardial Infarction

, 2009
Background: We analyzed whether digitoxin affects the survival of rats with congestive heart failure.Methods and Results: the influence of digitoxin (0.1 mg.
Flumignan, Ronald L. G. [UNIFESP], Gheorghiade, Mihai, Dos Santos, Alexandra A. [UNIFESP], Antonio, Ednei L. [UNIFESP], Bocalini, Danilo S. [UNIFESP], Helber, Izo [UNIFESP], Piccolo, Camila [UNIFESP], Tucci, Paulo J. F. [UNIFESP]   +7 more
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Exploring bacterial key genes and therapeutic agents for breast cancer among the Ghanaian female population: Insights from In Silico analyses.

PLoS ONE
Breast cancer (BC) is yet a significant global health challenge across various populations including Ghana, though several studies on host-genome associated with BC have been investigated molecular mechanisms of BC development and progression, and ...
Md Kaderi Kibria, Md Ahad Ali, Md Nurul Haque Mollah   +2 more
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Quantitation of Bacopaside I in Rat Biological Samples by LC-QTOF-MS/MS and Its Pharmacokinetic Application

Natural Product Communications, 2017
Bacopaside I is a triterpenoid saponin, a major compound in Bacopa monnieri , which exhibits several potentially useful clinical activities including memory enhancement.
Sontaya Sookying, Dumrongsak Pekthong, Sarawut Oo-Puthinan, Nitra Nuengchamnong, Kornkanok Ingkaninan   +4 more
doaj   +1 more source

The cardiotonic steroid digitoxin regulates alternative splicing through depletion of the splicing factors SRSF3 and TRA2B

, 2012
Modulation of alternative pre-mRNA splicing is a potential approach to therapeutic targeting for a variety of human diseases. We investigated the mechanism by which digitoxin, a member of the cardiotonic steroid class of drugs, regulates alternative ...
Anderson, Erik S., Stoilov, Peter, Black, Douglas L., Xiao, Xinshu, Burge, Christopher B, Lin, Chia-Ho   +5 more
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