Results 91 to 100 of about 4,113 (206)

Intron Retention of DDX39A Driven by SNRPD2 is a Crucial Splicing Axis for Oncogenic MYC/Spliceosome Program in Hepatocellular Carcinoma

open access: yesAdvanced Science
RNA splicing is a dynamic molecular process in response to environmental stimuli and is strictly regulated by the spliceosome. Sm proteins, constituents of the spliceosome, are key components that mediate splicing reactions; however, their potential role
Cunjie Chang   +31 more
doaj   +1 more source

The Renaissance of Digitoxin Is Overdue [PDF]

open access: yesDeutsches Ärzteblatt international, 2016
A 12-page review article on heart failure is very commendable (1). However, it is a source of irritation that in such a comprehensive article, a total of six lines is all that is given to the positive inotropic digitalis glycosides. A distinction between digoxin and digitoxin was not provided. Positive experiences have been reported for a long time for
openaire   +2 more sources

Multi-spectroscopic investigation of the binding interaction of fosfomycin with bovine serum albumin

open access: yesJournal of Pharmaceutical Analysis, 2015
The interaction between fosfomycin (FOS) and bovine serum albumin (BSA) has been investigated effectively by multi-spectroscopic techniques under physiological pH 7.4. FOS quenched the intrinsic fluorescence of BSA via static quenching.
Manjunath D. Meti   +4 more
doaj   +1 more source

The Therapeutic Effects of Digitoxine [PDF]

open access: yesThe American Journal of the Medical Sciences, 1894
n ...
openaire   +2 more sources

Stereochemical Survey of Digitoxin Monosaccharides

open access: yes, 2016
A stereochemically diverse array of monosaccharide analogues of the trisaccharide-based cardiac glycoside natural product digitoxin has been synthesized using a de novo asymmetric approach. The analogues were tested for cytotoxicity against the NCI panel
Todd A. Stueckle (1908121)   +5 more
core   +1 more source

CLINICAL NOTES ON DIGITOXIN. [PDF]

open access: yesJAMA: The Journal of the American Medical Association, 1899
Among the few really indispensable drugs which we have, digitalis would be placed in the very front rank by most medical men, and this is true in spite of the fact that its use is attended by certain disadvantages, and that these disadvantages are not regularly to be estimated, owing to the complex nature of the constituents of the drug, and the ...
openaire   +2 more sources

Accidental digitoxin intoxication: an interplay between laboratory and clinical medicine [PDF]

open access: yes, 2012
Introduction: Two Italian adults arrived at the Emergency Department referring diarrhea, nausea and vomiting for 4 days; weakness, fatigue and visual hallucinations were also complained of. Patients reported the ingestion of some leaves of a plant, which
Bellomo, Giorgio   +7 more
core   +1 more source

The Effect of Chronic Digitoxin Administration on the Contractile State of Normal and Nonfailing Hypertrophied Myocardium [PDF]

open access: yes, 2020
A B S T R A C T To determine the effect of prolonged digitoxin administration on contractile function of nonfailing myocardium, right ventricular papillary muscle mechanics were examined after 6 or 24 wk of glycoside administration to control and ...
Ralph D Potter, John F Willams, J R
core  

Effects of digitoxin on cell migration in ovarian cancer inflammatory microenvironment

open access: yes, 2018
Clinical and experimental evidence supports a role for cardiac glycosides (CGs) as potential novel anticancer drugs. However, there are no studies reporting the effect of CGs on the inflammatory tumor microenvironment (TME), which plays a central role in
Bolego, Chiara   +11 more
core   +1 more source

Digitoxinのモルモツト心電図に及ぼす影響 [PDF]

open access: yes
Electrocardiographic studies wers carried out on the heart action of digitoxin, by using guinea pigs subjected to injections of definite quantities of digitoxin at five minute intervals until heart standstill occurred. Electrocadiographic changes such as
藤野, 澄子
core   +2 more sources

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