Results 1 to 10 of about 43,790 (236)

Reconsidering Digoxin in Atrial Fibrillation: From Historical Controversy to Physiologically Guided and Personalized Rate Control [PDF]

Biomedicines
Background: The role of digoxin in atrial fibrillation, particularly in patients with heart failure, has long been debated. Observational studies reporting higher mortality have fueled skepticism, yet growing evidence suggests that these findings largely
Silvia Ana Luca, Adelina Andreea Faur-Grigori, Cristina Văcărescu, Dragos Cozma, Simina Crișan, Dan Gaiță, Mihai-Andrei Lazăr, Constantin-Tudor Luca   +7 more
doaj   +2 more sources

Digoxin toxicity with therapeutic serum digoxin concentrations [PDF]

Toxicology Reports
Introduction: Digoxin is a cardiac glycoside used for rate control in atrial fibrillation and heart failure. Despite its efficacy, digoxin has a narrow therapeutic window and can cause severe side effects, including life-threatening arrhythmias ...
J. Graafsma, N. Cimic, M. Dijkman, F.M.J. Gresnigt, D. Mitrovic, C. Smit   +5 more
doaj   +2 more sources

Impact of digoxin on sinus rhythm restoration after catheter ablation of persistent atrial fibrillation and drug-refractory atrial tachyarrhythmia recurrence: A cohort study [PDF]

Journal of International Medical Research
Objective Early rhythm control has demonstrated clinical benefits even among patients with persistent atrial fibrillation. However, some patients continue to experience recurrent atrial tachyarrhythmias despite undergoing catheter ablation and treatment ...
Yu-Sheng Lin, Hsiang-Hsuan Chen, Bang-Yan Hou, Hui-Ting Wang, Yung-Lung Chen   +4 more
doaj   +2 more sources

Induced Fetal Demise Prior to Later Medication Abortion: A Qualitative Study of Women's Experience With Digoxin Injection [PDF]

Public Health Challenges
Background Recent evidence suggests that providers who continue to use digoxin for induced fetal demise prior to later medication abortion should consider patient preferences in how they offer digoxin and consider tools to ensure patient understanding ...
Abraham Fessehaye Sium, Abrham Getachew, Tesfaye Tufa   +2 more
doaj   +2 more sources

Drug therapy monitoring (TDM) of Digoxin: safety and efficacy review [PDF]

Pharmacia, 2022
Digoxin was developed as a novel medication for the treatment of heart failure and atrial fibrillation (AF) 200 years ago. This investigation began with a PubMed and Google Scholar search for various papers using the terms digoxin safety and efficacy ...
Rony Abdi Syahputra, Urip Harahap, Aminah Dalimunthe, M. Pandapotan Nasution, Denny Satria   +4 more
doaj   +3 more sources

Effects of multiple doses of montmorillonite, alone and in combination with activated charcoal, on the toxicokinetics of a single dose of digoxin in rats [PDF]

Iranian Journal of Basic Medical Sciences, 2023
Objective(s): A narrow margin between the therapeutic and toxic doses of digoxin can result in an increased incidence of toxicity.  Since digoxin has an enterohepatic cycle, multiple oral doses of absorbents like montmorillonite may be useful in the ...
Fatemeh Heydarian, Mohamad Moshiri, Ali Roohbakhsh, Maryam Akaberi, Atoosa Haghighizadeh, Ameneh Ghadiri, Negar Yeganeh Khorasani, Leila Etemad   +7 more
doaj   +1 more source

Serum digoxin concentrations in dogs with atrial fibrillation under long term digoxin treatment [PDF]

Open Veterinary Journal, 2022
Background: Atrial fibrillation (AF) is the most common arrhythmia in dogs, most frequently diagnosed as chronic AF associated with a structural heart disease.
Antonella Colella, Serena Digiaro, Marco Fiorentino, Beatrice Greco, Mariateresa Sasanelli, Paola Paradies   +5 more
doaj   +1 more source

Utilization of Digoxin among Hospitalized Older Patients with Heart Failure and Atrial Fibrillation in Thailand: Prevalence, Associated Factors, and Clinical Outcomes [PDF]

Annals of Geriatric Medicine and Research, 2021
Background Digoxin is used to control heart rate in patients with heart failure (HF) and atrial fibrillation (AF). However, its use is often limited in older patients, as they are prone to digoxin toxicity. This study aimed to determine the prevalence of
Noppaket Singkham, Yuttana Wongsalap, Duangkamon Poolpun, Sirichok Phetnoo, Chuthalak Somkhon   +4 more
doaj   +1 more source

Patterns of Digoxin Prescribing for Medicare Beneficiaries in the United States 2013-2019

American Journal of Medicine Open, 2023
Background: Studies show that digoxin use is declining but is still prevalent. Recent data on digoxin prescription and characteristics of digoxin prescribers are unknown, which can help understand its contemporary use. Methods: Using Medicare Part D data
Claudia See, Kevin M. Wheelock, César Caraballo, Rohan Khera, Amarnath Annapureddy, Shiwani Mahajan, Yuan Lu, Harlan M. Krumholz, Karthik Murugiah   +8 more
doaj   +1 more source

The Effect of Different Doses of Intraamniotic Digoxin on the Timing of Fetal Demise in Second Trimester Medical Abortions

Gynecology Obstetrics & Reproductive Medicine, 2022
OBJECTIVES: The World Health Organization recommends feticide for termination of pregnancy after 20 weeks of gestation, and the Royal College of Obstetricians & Gynecologists after 21 weeks and 6 days. Digoxin is a commonly used feticidal agent.
Gulsah Aynaoglu Yildiz, Ragip Atakan Al
doaj   +1 more source