Effect of green tea catechins on the pharmacokinetics of digoxin in humans
Drug Design, Development and Therapy, 2018 Tae-Eun Kim,1 Kwang-Hee Shin,2 Jeong-Eun Park,2 Min-Gul Kim,3 Yeo-Min Yun,4 Dong-Hee Choi,5 Kyoung Ja Kwon,5 Jongmin Lee6 1Department of Clinical Pharmacology, Konkuk University Medical Center, Seoul, Republic of Korea; 2Department of Pharmacotherapy ...
Kim TE +7 more
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Digoxin Suppresses Tumor Malignancy through Inhibiting Multiple Src-Related Signaling Pathways in Non-Small Cell Lung Cancer. [PDF]
PLoS ONE, 2015 Non-small cell lung cancer is the predominant type of lung cancer, resulting in high mortality worldwide. Digoxin, a cardiac glycoside, has recently been suggested to be a novel chemotherapeutic agent.
Sheng-Yi Lin +7 more
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Digoxin, an Overlooked Agonist of RORγ/RORγT
Frontiers in Pharmacology, 2019 Digoxin was one of the first identified RORγT receptor inverse agonists inhibiting the differentiation of Th17 cells. However, this compound exhibits inhibitory activity at relatively high concentrations that mediate cytotoxic effects.
Kaja Karaś +7 more
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Drug therapy monitoring (TDM) of Digoxin: safety and efficacy review [PDF]
Pharmacia, 2022 Digoxin was developed as a novel medication for the treatment of heart failure and atrial fibrillation (AF) 200 years ago. This investigation began with a PubMed and Google Scholar search for various papers using the terms digoxin safety and efficacy ...
Rony Abdi Syahputra +4 more
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Effects of multiple doses of montmorillonite, alone and in combination with activated charcoal, on the toxicokinetics of a single dose of digoxin in rats [PDF]
Iranian Journal of Basic Medical Sciences, 2023 Objective(s): A narrow margin between the therapeutic and toxic doses of digoxin can result in an increased incidence of toxicity. Since digoxin has an enterohepatic cycle, multiple oral doses of absorbents like montmorillonite may be useful in the ...
Fatemeh Heydarian +7 more
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Utilization of Digoxin among Hospitalized Older Patients with Heart Failure and Atrial Fibrillation in Thailand: Prevalence, Associated Factors, and Clinical Outcomes [PDF]
Annals of Geriatric Medicine and Research, 2021 Background Digoxin is used to control heart rate in patients with heart failure (HF) and atrial fibrillation (AF). However, its use is often limited in older patients, as they are prone to digoxin toxicity. This study aimed to determine the prevalence of
Noppaket Singkham +4 more
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Serum digoxin concentrations in dogs with atrial fibrillation under long term digoxin treatment [PDF]
Open Veterinary Journal, 2022 Background: Atrial fibrillation (AF) is the most common arrhythmia in dogs, most frequently diagnosed as chronic AF associated with a structural heart disease.
Antonella Colella +5 more
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Annals of the Rheumatic Diseases, 2021 Objectives Dysregulated chondrocyte metabolism is closely associated with the pathogenesis of osteoarthritis (OA). Suppressing chondrocyte catabolism to restore cartilage homeostasis has been extensively explored, whereas far less effort has been ...
Kai-di Wang +11 more
semanticscholar +1 more source
Detecting Digoxin Toxicity by Artificial Intelligence-Assisted Electrocardiography
International Journal of Environmental Research and Public Health, 2021 Although digoxin is important in heart rate control, the utilization of digoxin is declining due to its narrow therapeutic window. Misdiagnosis or delayed diagnosis of digoxin toxicity is common due to the lack of awareness and the time-consuming ...
Da-Wei Chang +7 more
semanticscholar +1 more source
Frontiers in Cardiovascular Medicine, 2023 The current recommendations for monitoring digoxin, a narrow therapeutic index drug, are limited to confirming medication use or investigating suspicion of toxicity and fail our oath to do no harm.
Sridhar Rao Gona +5 more
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