Results 1 to 10 of about 42,520 (267)
Digoxin toxicity with therapeutic serum digoxin concentrations [PDF]
Toxicology ReportsIntroduction: Digoxin is a cardiac glycoside used for rate control in atrial fibrillation and heart failure. Despite its efficacy, digoxin has a narrow therapeutic window and can cause severe side effects, including life-threatening arrhythmias ...
J. Graafsma +5 more
doaj +3 more sources
Radioimmunoassay of serum digoxin in relation to digoxin intoxication. [PDF]
Heart, 1975 Serum digoxin estimations were done in 98 patients receiving digoxin for heart failure of varied aetiology. Digoxin toxicity or the lack of it was determined on the basin of established electrocardiographic criteria. Fifty-two patients were classified as 'toxic' and 46 as 'non-toxic'. The difference is the mean digoxin levels between the two groups was
Ram B. Singh +5 more
openalex +4 more sources
Drug therapy monitoring (TDM) of Digoxin: safety and efficacy review [PDF]
Pharmacia, 2022 Digoxin was developed as a novel medication for the treatment of heart failure and atrial fibrillation (AF) 200 years ago. This investigation began with a PubMed and Google Scholar search for various papers using the terms digoxin safety and efficacy ...
Rony Abdi Syahputra +4 more
doaj +3 more sources
Effects of multiple doses of montmorillonite, alone and in combination with activated charcoal, on the toxicokinetics of a single dose of digoxin in rats [PDF]
Iranian Journal of Basic Medical Sciences, 2023 Objective(s): A narrow margin between the therapeutic and toxic doses of digoxin can result in an increased incidence of toxicity. Since digoxin has an enterohepatic cycle, multiple oral doses of absorbents like montmorillonite may be useful in the ...
Fatemeh Heydarian +7 more
doaj +1 more source
Serum digoxin concentrations in dogs with atrial fibrillation under long term digoxin treatment [PDF]
Open Veterinary Journal, 2022 Background: Atrial fibrillation (AF) is the most common arrhythmia in dogs, most frequently diagnosed as chronic AF associated with a structural heart disease.
Antonella Colella +5 more
doaj +1 more source
Utilization of Digoxin among Hospitalized Older Patients with Heart Failure and Atrial Fibrillation in Thailand: Prevalence, Associated Factors, and Clinical Outcomes [PDF]
Annals of Geriatric Medicine and Research, 2021 Background Digoxin is used to control heart rate in patients with heart failure (HF) and atrial fibrillation (AF). However, its use is often limited in older patients, as they are prone to digoxin toxicity. This study aimed to determine the prevalence of
Noppaket Singkham +4 more
doaj +1 more source
Patterns of Digoxin Prescribing for Medicare Beneficiaries in the United States 2013-2019
American Journal of Medicine Open, 2023 Background: Studies show that digoxin use is declining but is still prevalent. Recent data on digoxin prescription and characteristics of digoxin prescribers are unknown, which can help understand its contemporary use. Methods: Using Medicare Part D data
Claudia See +8 more
doaj +1 more source
Gynecology Obstetrics & Reproductive Medicine, 2022 OBJECTIVES: The World Health Organization recommends feticide for termination of pregnancy after 20 weeks of gestation, and the Royal College of Obstetricians & Gynecologists after 21 weeks and 6 days. Digoxin is a commonly used feticidal agent.
Gulsah Aynaoglu Yildiz, Ragip Atakan Al
doaj +1 more source
Frontiers in Cardiovascular Medicine, 2021 Background: Whether digoxin is associated with increased mortality in atrial fibrillation (AF) remains controversial. We aimed to assess the risk of mortality and clinical effects of digoxin use in patients with AF.Methods: PubMed, Embase, and the ...
Xiaoxu Wang, Yi Luo, Dan Xu, Kun Zhao
doaj +1 more source
Frontiers in Cardiovascular Medicine, 2023 The current recommendations for monitoring digoxin, a narrow therapeutic index drug, are limited to confirming medication use or investigating suspicion of toxicity and fail our oath to do no harm.
Sridhar Rao Gona +5 more
doaj +1 more source