Results 91 to 100 of about 39,814 (206)

Does digoxin cause more harm than good?

, 2019
Background: The most recent British National Formulary recommends digoxin therapy for patients with heart failure (HF) and/or supraventricular arrhythmias, particularly atrial fibrillation (AF) and atrial flutter.
Reed, Grace
core   +1 more source

Rate Versus Rhythm Control in a Multimorbid Patient With Tachy–Brady Syndrome: Evaluation of Clinical Outcomes and Pacing Dependency

Clinical Case Reports, Volume 14, Issue 6, June 2026.
ABSTRACT This case report describes a 77‐year‐old man with multiple comorbidities, including atrial fibrillation, heart failure with mildly reduced ejection fraction, hypertension, diabetes mellitus, and prior coronary artery bypass grafting, who presented with severe hypertension and dyspnoea.
Reem Fakak, Emma Nordahl, Joseph Moutiris   +2 more
wiley   +1 more source

Effects of Sheep Digoxin-Specific Antibodies and Their Fab Fragments on Digoxin Pharmacokinetics in Dogs

, 2014
and their Fab fragments have both been found to exert profound effects on digoxin pharmacokinetics in [3H]digoxin-treated dogs. Both classes of molecule remove digoxin from the extravascular space and sequester it in the circulation in protein-bound form,
Thomas W. Smith, Vincent P. Butler, B. Denise Raynor, Paul Demartini, Edgar Haber, Donald H. Schmidt   +5 more
core  

Appropriateness of digoxin measurement in hospitalized patients

, 2017
Introduction: Measurement of serum digoxin concentrations before steady-state is reached results in a falsely low concentration, and may affect treatment safety.
Ozgur Aslan, Ucku, Reyhan S, Seyma Oncu, Oncu, Seyma, Reyhan S Ucku, Ucku, Reyhan S., Gelal, Ayse, Ayse Gelal, Aslan, Ozgur   +8 more
core   +1 more source

Peripartum Cardiomyopathy Presenting With Severe Biventricular Dysfunction, Valvular Regurgitation, and Familial Predisposition: A Case Report

Clinical Case Reports, Volume 14, Issue 6, June 2026.
ABSTRACT Peripartum cardiomyopathy (PPCM) is defined as the onset of left ventricular systolic dysfunction either during pregnancy or up to 5 months after delivery, without any other known cause of heart failure. The exact pathogenesis of this disease is unknown, and its prognosis remains poorly understood.
Muhammad Ibrahim Shah, Hasnain Wajeeh Saqib, Maaz Khan, Muhammad Saeed Ullah Shah, Dadullah Faiz   +4 more
wiley   +1 more source

Digoxin Poisoning and Anuric Acute Renal Failure: Efficiency of the Treatment Associating Digoxin-Specific Antibodies (Fab) and Plasma Exchanges

, 2002
Digoxin-specific antibodies (Fab) are currently the treatment of choice for digoxin intoxication. These fragments bind to digoxin, leading to Fab-digoxin complexes, and promote the release of receptor-bound digoxin. These complexes are renally excreted.
N. Vincent, M. Boazis, B. Barbier, P. Chillet, L. Poiron, PH. Berger, D. Petitpas, J.M. Korach   +7 more
core   +1 more source

No relevant pharmacokinetic interaction between the KRAS G12C inhibitor sotorasib and the direct oral anticoagulant rivaroxaban in healthy subjects

International Journal of Cancer, Volume 158, Issue 11, Page 2920-2927, 1 June 2026.
What's new? Venous thromboembolism (VTE) is common in cancer patients, with direct oral anticoagulants, including rivaroxaban, recommended as first‐line therapy. However, oral anticoagulant use is limited due to the growing use of targeted therapy and concerns about drug‐drug interactions.
Esther M. Hollander, Alessandra I. G. Buma, Jenneke Leentjens, Paddy K. C. Janssen, Michel M. van den Heuvel, David M. Burger, Berber Piet, Rob ter Heine   +7 more
wiley   +1 more source

CRISPR‐Cas13a/Cas12a Assisted Dual Portable and Visualized HDV and HBV Detection

Journal of Medical Virology, Volume 98, Issue 6, June 2026.
ABSTRACT Co‐infection with both hepatitis B virus (HBV) and hepatitis D virus (HDV) can aggravate the severity of the end‐stage liver disease and accelerate its progression. However, no combined diagnostic method for HDV and HBV nucleic acids exists. In this study, we have developed a highly sensitive and specific dual detection method for HDV RNA and ...
Yuan Tian, Yaling Cao, Zhenzhen Pan, Ling Xu, Zihao Fan, Yinkang Mo, Xianru Zhu, Xiangying Zhang, Hao Li, Shengtao Zeng, Feng Ren   +10 more
wiley   +1 more source

Pharmacokinetic evaluation of the digoxin-amiodarone interaction

, 1985
Amiodarone is known to raise serum digoxin levels. This study was designed to evaluate the pharmacokinetic basis of this interaction in 10 normal subjects.
White, Neal W., Fenster, Paul E., Hanson, Christine D.   +2 more
core   +1 more source

Suspected Cardioembolic Stroke Linked to Left Atrial Stunning After Pulsed Field Ablation for Atrial Fibrillation

Journal of Arrhythmia, Volume 42, Issue 3, June 2026.
After pulsed field ablation with pulmonary vein and posterior wall isolation, a patient developed ischemic stroke due to left carotid artery occlusion. Pathology of the retrieved thrombus revealed an acute red thrombus, suggesting left atrial stunning–induced thrombus formation.
Akinori Matsushima, Takamichi Katsuhara, Tomonobu Kodama, Kenta Uto, Yasuo Okumura   +4 more
wiley   +1 more source