Results 81 to 90 of about 36,624 (198)

Comparative Effectiveness of GLP‐1RAs, SGLT2is and DPP4is for Cardiovascular Outcomes in Type 2 Diabetes: An Empirically Calibrated Target Trial Emulation Study

open access: yes
Diabetes, Obesity and Metabolism, EarlyView.
Bingyu Zhang   +9 more
wiley   +1 more source

Integrated Phytochemical Characterisation, Pharmacological Evaluation and Computational Investigation of Acampe papillosa Stem Extract

open access: yesAnalytical Science Advances, Volume 7, Issue 2, December 2026.
The pharmacological potential of the methanolic stem extract of Acampe papillosa is evaluated using in vivo and in silico approaches. The extract demonstrates significant anxiolytic, sedative, anti‐inflammatory, and antipyretic activities in experimental models, while molecular docking supports the observed biological effects through favorable ...
Qurratul Ain Sadia   +10 more
wiley   +1 more source

Impact of digoxin on sinus rhythm restoration after catheter ablation of persistent atrial fibrillation and drug-refractory atrial tachyarrhythmia recurrence: A cohort study

open access: yesJournal of International Medical Research
Objective Early rhythm control has demonstrated clinical benefits even among patients with persistent atrial fibrillation. However, some patients continue to experience recurrent atrial tachyarrhythmias despite undergoing catheter ablation and treatment ...
Yu-Sheng Lin   +4 more
doaj   +1 more source

Severe Digoxin Toxicity in a Child Managed with Cholestyramine. A Case Report

open access: yesSaudi Journal of Emergency Medicine
Digoxin toxicity is a common problem in clinical practice because its therapeutic window is relatively narrow (from 0.5 to 2 ng/ml). The toxic effects occur at concentrations > 2.8 ng/ml and are mainly related to disturbances of cardiac function and ...
Suman Noorani   +3 more
doaj   +1 more source

Cervical ectopic pregnancy at 22 weeks: A case with subsequent pregnancy outcome

open access: yesPregnancy, Volume 2, Issue 6, November 2026.
Abstract Introduction Cervical ectopic pregnancies are rare ectopic pregnancies inherently associated with abnormal placentation. Fertility‐sparing management of cervical ectopic pregnancy can have benefits for the patient, but such treatment strategies are less successful in the second trimester.
Joyce Y. Wang   +3 more
wiley   +1 more source

Safety and Feasibility of Magnetic Separation‐Based Blood Purification

open access: yesAdvanced NanoBiomed Research, Volume 6, Issue 10, October 2026.
We present the preclinical biological safety and translational feasibility of a magnetic nanoparticle‐based extracorporeal blood purification platform for removal of disease‐causing blood factors. ISO 10993‐compliant studies and exaggerated worst‐case exposure models demonstrate efficient nanoparticle extraction (≥99.9%), favorable biocompatibility ...
Carlos A. Mora   +11 more
wiley   +1 more source

Catheter Ablation Versus Medical Therapy in Atrial Fibrillation With Heart Failure With Reduced or Mildly Reduced Ejection Fraction: A GRADE‐Assessed Systematic Review and Meta‐Analysis

open access: yesJournal of Arrhythmia, Volume 42, Issue 5, October 2026.
In patients with atrial fibrillation and HFmrEF/HFrEF, catheter ablation was associated with lower mortality and improved cardiac function compared with conventional medical therapy, while cardiovascular hospitalization was not significantly reduced. The overall certainty of evidence ranged from moderate to high.
Aleena Amir Malik   +20 more
wiley   +1 more source

Effect of green tea catechins on the pharmacokinetics of digoxin in humans

open access: yesDrug Design, Development and Therapy, 2018
Tae-Eun Kim,1 Kwang-Hee Shin,2 Jeong-Eun Park,2 Min-Gul Kim,3 Yeo-Min Yun,4 Dong-Hee Choi,5 Kyoung Ja Kwon,5 Jongmin Lee6 1Department of Clinical Pharmacology, Konkuk University Medical Center, Seoul, Republic of Korea; 2Department of Pharmacotherapy ...
Kim TE   +7 more
doaj  

Fruquintinib: Mechanism of Action, Clinical, and Translational Science

open access: yesClinical and Translational Science, Volume 19, Issue 10, October 2026.
ABSTRACT Fruquintinib is a highly selective, oral inhibitor of all three vascular endothelial growth factor receptors (‐1, ‐2, and ‐3) that was approved, including in China, the United States, and the European Union, for the treatment of previously treated metastatic colorectal cancer (mCRC).
Xiaofei Zhou   +7 more
wiley   +1 more source

From Real World Data to Real Impact: A Co‐Medication Framework for Lung Cancer to Advance DDI Assessment and Patient‐Centric Drug Development

open access: yesClinical and Translational Science, Volume 19, Issue 10, October 2026.
ABSTRACT Lung cancer predominantly affects older adults who already experience comorbidities and are at increased risk of drug–drug interactions (DDIs) due to polypharmacy. Traditional DDI assessments often do not fully capture complex co‐medication patterns observed in real‐world practice due to the risk of introducing confounding factors.
Mareena Biju   +6 more
wiley   +1 more source

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