Results 61 to 70 of about 39,814 (206)
CPT: Pharmacometrics &Systems Pharmacology, Volume 14, Issue 3, Page 523-539, March 2025.Abstract Ritonavir (RTV) is a potent CYP3A inhibitor that is widely used as a pharmacokinetic (PK) enhancer to increase exposure to select protease inhibitors. However, as a strong and complex perpetrator of CYP3A interactions, RTV can also enhance the exposure of other co‐administered CYP3A substrates, potentially causing toxicity.
Lien Thi Ngo +5 more
wiley +1 more source
, 2018 [[abstract]]Purpose: The present study compared the risk of ischemic stroke in atrial fibrillation (AF) patients receiving digoxin and amiodarone. Methods: A retrospective cohort study was conducted using the longitudinal population-based database of ...
Kuan-Cheng, L;Lai, Kuan-Cheng;Chen, Sy-Jou;Chen, Sy-Jou;Chin-Sheng, L;Lin, Chin-Sheng;Yang, Fu-Chi;Yang, Fu-Chi;Lin, Cheng-Li;Lin, Cheng-Li;Hs, Chin-Wang;Hsu, Chin-Wang;Hua, Wen-Chen;Huang, Wen-Chen;高嘉鴻;Kao, Chia-Hung;*
core
Digoxin-quinidine interaction in the neonatal dog
, 1986 The effects of quinidine on steady state serum and tissue digoxin concentrations in the neonatal dog were studied. To determine the effects of quinidine on serum digoxin concentrations, two groups of neonates were evaluated: Group I (n = 11) was ...
Gelband, Henry +2 more
core +1 more source
Acta Ophthalmologica, EarlyView.Abstract Purpose To identify associations between systemic drugs and cataract surgery in Finland. Methods A historic cohort study based on administrative data. Endpoint event was cataract surgery. Use of drugs in question was based on redeemed prescriptions and consisted of 156 drugs.
Antti Riikonen +3 more
wiley +1 more source
The effect of digoxin dosage on the digoxin—quinidine interaction in the bile duct-cannulated rat
, 1987 Pretreating anaesthetized bile duct-cannulated rats with 9 mg kg−1 quinidine significantly decreased the cumulative biliary excretion of digoxin and its metabolites after 10 or 100 μg kg−1 [3H]digoxin, although the effect was more marked in animals ...
D S Hewick, T Ostenfeld
core +1 more source
Equine Veterinary Education, EarlyView.Summary A 4‐year‐old, 6‐month pregnant, Welsh pony mare presented with severe acute clinical signs including depression, anorexia, pale mucous membranes, tachycardia with a grade 4/6 holosystolic murmur and moderate expiratory dyspnoea with diffuse wheezes. There was no evidence of placentitis or fetal distress.
M. F. David +4 more
wiley +1 more source
Pharmacokinetic interactions between digoxin and other drugs
, 1985 Drug interactions with digoxin are important because of this agent's narrow therapeutic index. Among the drugs that can decrease digoxin bioavailability are cholestyramine, antacid gels, kaolin-pectate, certain antimicrobial drugs and cancer ...
Marcus, Frank I., Frank I. Marcus
core +1 more source
Hepatology Research, EarlyView.ABSTRACT Aim The aim of this all‐case post‐marketing study was to evaluate the real‐world safety and effectiveness in all children and adolescents with chronic hepatitis C with or without compensated cirrhosis treated with glecaprevir/pibrentasvir (G/P) in Japan. Methods This prospective, observational post‐marketing surveillance study was conducted at
Tatsuki Mizuochi +6 more
wiley +1 more source
, 2012 The mechanism by which quinidine affects hepatic digoxin pharmacokinetics remains controversial. Here, we study the role of displacement of digoxin from hepatic sinusoidal binding sites by quinidine.
Weiss, Michael +2 more
core +1 more source
, 2020 Digoxin is a cardiac glycoside that is used for the treatment of heart failure and atrial fibrillation. Besides its careful close follow-up, toxicity affects nearly 1% of congestive heart failure patients.
Aysun Fatma Dogan +9 more
core +1 more source