Results 51 to 60 of about 58,682 (199)

Association of Digoxin With Interstage Mortality: Results From the Pediatric Heart Network Single Ventricle Reconstruction Trial Public Use Dataset

Journal of the American Heart Association : Cardiovascular and Cerebrovascular Disease, 2016
Background Mortality for infants with single ventricle congenital heart disease remains as high as 8% to 12% during the interstage period, the time between discharge after the Norwood procedure and before the stage II palliation.
M. Oster, M. Kelleman, C. McCracken, R. Ohye, W. Mahle   +4 more
semanticscholar   +1 more source

Pharmacokinetics, Safety, and Efficacy of Intravitreal Digoxin in Preclinical Models for Retinoblastoma [PDF]

, 2015
PURPOSE:To assess in vitro cytotoxic activity and antiangiogenic effect, ocular and systemic disposition, and toxicity of digoxin in rabbits after intravitreal injection as a potential candidate for retinoblastoma treatment.METHODS:A panel of two ...
Abramson, David, Arana, Eloisa, Buitrago, Emiliano, Chantada, Guillermo Luis, Croxatto, Juan Oscar, del Sole, Maria Jose, Djaballah, Hakim, Francis, Jasmine, Laurent, Viviana Eunice, Mena, Hebe Agustina, Negrotto, Soledad, Schaiquevich, Paula Susana, Sgroi, Mariana, Winter, Ursula Andrea   +13 more
core   +2 more sources

Modelling the influence of MDR1 polymorphism on digoxin pharmacokinetic parameters. [PDF]

, 2007
OBJECTIVES: Digoxin is a well-known probe for the activity of P-glycoprotein. The objective of this work was to apply different methods for covariate selection in non-linear mixed-effect models to study the relationship between the pharmacokinetic ...
Becquemont, Laurent, Comets, Emmanuelle, Jaillon, Patrice, Lavielle, Marc, Mentré, France, Verstuyft, Céline   +5 more
core   +3 more sources

Atrial standstill in a horse with cardiac glycoside intoxication [PDF]

, 2012
C
De Clercq, Dominique, Decloedt, Annelies, Lefère, Laurence, van Loon, Gunther, Verheyen, Tinne   +4 more
core   +1 more source

Declining risk of sudden death in heart failure [PDF]

, 2017
No abstract ...
Jhund, Pardeep S., McMurray, John J.V., Shen, Li   +2 more
core   +1 more source

Systematic review and meta-analysis of mortality and digoxin use in atrial fibrillation.

Cardiology Journal, 2016
BACKGROUND There is growing controversy regarding the association between digoxin and mortality in atrial fibrillation (AF). The aim of this analysis was to systematically review digoxin use and risk of mortality in patients with AF.
W. Qureshi, Wesley T. O’Neal, E. Soliman, M. Al-Mallah   +3 more
semanticscholar   +1 more source

The alpha-synuclein 5'untranslated region targeted translation blockers: anti-alpha synuclein efficacy of cardiac glycosides and Posiphen [PDF]

, 2011
Increased brain α-synuclein (SNCA) protein expression resulting from gene duplication and triplication can cause a familial form of Parkinson's disease (PD).
Bandyopadhyay, Sanghamitra, Cahill, Catherine M., Castelvetri, Ippolita Cantuti, Greig, Nigel H., Huang, Xudong, Lahiri, Debomoy K., Maccecchini, Maria L., Mikkilineni, Sohan, Rogers, Jack T., Smith, Deborah H.   +9 more
core   +1 more source

Digoxin

Journal of the American College of Cardiology, 2015
The digitalis glycosides (digoxin) have been ensconced by history, efficacy, therapeutic necessity, and lack of definitive evidence as treatments for both heart failure (HF) and atrial fibrillation (AF).
Todd F. Dardas, Wayne C. Levy
openaire   +3 more sources

Digoxin Suppresses Tumor Malignancy through Inhibiting Multiple Src-Related Signaling Pathways in Non-Small Cell Lung Cancer

PLoS ONE, 2015
Non-small cell lung cancer is the predominant type of lung cancer, resulting in high mortality worldwide. Digoxin, a cardiac glycoside, has recently been suggested to be a novel chemotherapeutic agent.
Sheng-Yi Lin, Hsiu-Hui Chang, Yi-Hua Lai, Ching-Hsiung Lin, Min-Hsuan Chen, G. Chang, Meng-Feng Tsai, Jeremy J. W. Chen   +7 more
semanticscholar   +1 more source

Prevalence of prediabetes and undiagnosed diabetes in patients with HFpEF and HFrEF and associated clinical outcomes [PDF]

, 2017
Purpose: The prevalence and consequences of prediabetic dysglycemia and undiagnosed diabetes is unknown in patients with heart failure (HF) and preserved ejection fraction (HFpEF) and has not been compared to heart failure and reduced ejection ...
Christopher B. Granger, John J. V. McMurray, Karl Swedberg, Lars Køber, Marc A. Pfeffer, Matthew M. Y. Lee, null null, Pardeep S. Jhund, Salim Yusuf, Scott D. Solomon, Søren L. Kristensen   +10 more
core   +3 more sources