Results 111 to 120 of about 11,186 (206)

Dihydroartemisinin decreases pre-existing neutralizing antibodies against adeno-associated virus in challenged mice

Frontiers in Pharmacology
IntroductionThe high prevalence of pre-existing neutralizing antibodies (NAbs) against adeno-associated virus (AAV) poses a major obstacle to in vivo gene therapy.
Jingjing Fang, Enze Cui, Jinyan Xie, Xuxia Gao, Yun He, Ming Yang, Sana Shaheen, Zhengjun Zhou, Shaolai Zhou, Binbin Cheng, Binbin Cheng, Changquan Ling, Changquan Ling, Chen Ling, Chen Ling, Chen Ling   +15 more
doaj   +1 more source

Crystal structure of (3R,5aS,6R,9R,12R,12aR)-3,6,9-trimethyldecahydro-12H-3,12-epoxy[1,2]dioxepino[4,3-i]isochromen-10-yl 5-((3aS,4S,6aR)-2-oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl)pentanoate

Acta Crystallographica Section E: Crystallographic Communications
In the title biotin-conjugated dihydroartemisinin (DHA) derivative, C25H38N2O7S, the molecule retains the essential endoperoxide bridge and links the C-10 position of DHA to the pentanoate chain of biotin via an ester bond.
Xiaomei Yang, Siyu Chen, Wenxin Liu, Mengjie Cui, Qingjie Zhao   +4 more
doaj   +1 more source

Method and apparatus for the synthesis of dihydroartemisinin and artemisinin derivatives [PDF]

, 2015
The present invention is directed to a method for continuous production of dihydroartemisinin and also artemisinin derivatives derived from dihydroartemisinin by using artemisinin or dihydroartemisinic acid (DHAA) as starting material as well as to a ...
Kopetzki, D., McQuade, D., Gilmore, K., Seeberger, P.   +3 more
core  

Dihydroartemisinin Sensitizes Lung Cancer Cells to Cisplatin Treatment by Upregulating ZIP14 Expression and Inducing Ferroptosis

Cancer Medicine
Background Despite significant advances in lung cancer treatment, cisplatin (DDP)‐based chemotherapy remains a cornerstone for managing the disease. However, the prevalence of chemoresistance presents a major challenge, limiting its effectiveness and ...
Zhuoying Yang, Zehao Zhou, Qingyu Meng, Zhijie Chen, Liang Yun, Jianjun Jiang, Yujing He, Meijuan Dian, Ruihao Zhang, Haotian Ge, Tianbao Yan, Biying Men, Zichao Li, Xu Wu, Junming He, Shuan Rao   +15 more
doaj   +1 more source

Inhalable Albumin Nanoparticles Co-Delivering Dihydroartemisinin and Nintedanib Attenuate Pulmonary Fibrosis by Suppressing TGF-β1/Smad2/3 Signaling

International Journal of Nanomedicine
Caopei Zheng,1,2,* Wei Ding,3,* Yuqing Sun,1,2 Yu Wang,1 Yulin Zhang1,2,4 1Department of Respiratory and Critical Care Medicine, Beijing Youan Hospital, Capital Medical University, Beijing, People’s Republic of China; 2Laboratory for ...
Zheng C, Ding W, Sun Y, Wang Y, Zhang Y
doaj  

Dihydroartemisinin Modulates Enteric Glial Cell Heterogeneity to Alleviate Colitis

Advanced Science
The precise mechanism underlying the therapeutic effects of dihydroartemisinin (DHA) in alleviating colitis remains incompletely understood. A strong correlation existed between the elevation of glial fibrillary acidic protein (GFAP)+/S100 calcium ...
Peishan Qiu, Ying Chang, Xiaoyu Chen, Shaoqi Wang, Haihang Nie, Yuntian Hong, Meng Zhang, Haizhou Wang, Cong Xiao, Yuhua Chen, Lan Liu, Qiu Zhao   +11 more
doaj   +1 more source

Resistance to Dihydroartemisinin (Reply) [PDF]

Emerging Infectious Diseases, 2007
Sandrine Cojean, Véronique Hubert, Jacques Le Bras, Rémy Durand   +3 more
openaire   +1 more source

Correction: Codelivery of dihydroartemisinin and doxorubicin in mannosylated liposomes for drug-resistant colon cancer therapy. [PDF]

Acta Pharmacol Sin
Kang XJ, Wang HY, Peng HG, Chen BF, Zhang WY, Wu AH, Xu Q, Huang YZ.   +7 more
europepmc   +1 more source

Terpenoids as Emerging Senotherapeutics: Mechanistic Insights and Therapeutic Potential. [PDF]

Int J Mol Sci
Yi S, Park JY, Lee SJ.
europepmc   +1 more source

Initial Evaluation of Dihydroartemisinin (DHA), Metformin and Taro Extract in Combination with Cisplatin for Enhanced Cytotoxicity in Triple-Negative Breast Cancer (TNBC) Cell Lines. [PDF]

J Anal Oncol
Godwin AM, Ward N, Krauss C, Banerjee H, Payne G, Adedeji D.   +5 more
europepmc   +1 more source