Results 91 to 100 of about 11,186 (206)

Design, Synthesis and Evaluation of the Antibacterial Enhancement Activities of Amino Dihydroartemisinin Derivatives

Molecules, 2013
Artemisinin (ART) and its derivatives artesunate (AS), dihydroartemisinin (DHA) are a group of drugs containing a sesquiterpene lactone used to treat malaria.
Dacheng Yang, Jingfang Wang, Wei Peng, Bin Li, Wenying Xian, Xichun Pan, Jian Liu, Chong Wu, Hong Zhou   +8 more
doaj   +1 more source

ATF4/SCO2 Inhibits Ferroptosis in Lung Cancer Through Activating the MAPK Signaling Pathway

Journal of Biochemical and Molecular Toxicology, Volume 40, Issue 8, August 2026.
ATF4 activates the transcription of SCO2 to increase SCO2 expression that further stimulates p38/ERK1 signals in MAPK pathway, ultimately promoting proliferation and migration while inhibiting apoptosis and ferroptosis of lung cancer cells. ABSTRACT Ferroptosis is a specific cell death form resulting from the iron‐dependent lipid peroxidation ...
Liang Yu, Sheng Zhang, Jinxi He, Bo Ma, Xuyang Song, Rui Qiu, Bo Yu   +6 more
wiley   +1 more source

Biocompatible Sulfobetaine Polymer‐Artemisinin Conjugates Inducing Ferroptosis in Cancer Cells: Synthesis by Mechanochemical Solid‐State Polymerization and Characterization

Macromolecular Rapid Communications, Volume 47, Issue 15, 4 August 2026.
The amphiphilic copolymer incorporating a hydrophobic chain conjugated with artesunate into a biocompatible sulfobetaine polymer is synthesized by solid‐state copolymerization of sulfobetaine methacrylate and methacrylamide derivative conjugating artesunate.
Naoki Doi, Yukinori Yamauchi, Yasushi Sasai, Ryosuke Nagai, Ayaka Koike, Madoka Ikawa, Toru Yoshimoto, Satoshi Yamada, Masayuki Kuzuya, Shin‐ichi Kondo   +9 more
wiley   +1 more source

Simultaneous identification of species and molecular forms of the Anopheles gambiae complex by PCR-RFLP.

, 2002
For differential identification of sibling species in the Anopheles gambiae Giles complex (Diptera: Culicidae), including simultaneous separation of M and S molecular forms within An. gambiae Giles sensu stricto, we describe a PCR-RFLP method.
SANTOLAMAZZA, FEDERICA, della Torre, A, A. Della Torre, DELLA TORRE, Alessandra, F. Santolamazza, Fanello, C, FANELLO C, C. Fanello, Fanello, Caterina, Santolamazza, F   +9 more
core   +1 more source

Potential Cosmetic Applications of Dihydroartemisinin

Molecules
In recent years, active monomers derived from Chinese herbal medicine and their derivatives have attracted significant attention in the field of skincare product development. Artemisinin and its derivatives, including dihydroartemisinin (DHA), exhibit diverse pharmacological activities such as anti-inflammatory, antibacterial, immunomodulatory, and ...
Yifan Zhao, Mo Chen, Ying Zheng, Le Zhu, Cui Wu, Yue Ma, Ya Zhao, Dong Zhang, Haidong Jia, Lan Yang   +9 more
openaire   +2 more sources

Dihydroartemisinin-Ursodeoxycholic Bile Acid Hybrids in the Fight against SARS-CoV‑2

Here, we propose the molecular hybridization of dihydroartemisinin (DHA) and ursodeoxycholic bile acid (UDCA), approved drugs, for the preparation of antiviral agents against SARS-CoV-2.
Elena Marchesi (1921495), Virginia Cristofori (5961347), Anna Fantinati (1372728), Roberta Rizzo (304289), Claudio Trapella (1372722), Daniela Perrone (1921498), Paolo Marchetti (393307), Maria Luisa Navacchia (1921501), Valentina Gentili (2244499), Daria Bortolotti (3159762), Lorenzo Preti (17391114)   +10 more
core   +1 more source

Malaria diagnosis under field conditions in the Venezuelan Amazon.

, 2008
To improve practical, accurate diagnosis of malaria in the Amazon rainforest of Venezuela, two rapid diagnostic tests (RDT) (OptiMAL-IT) and FalciVax) and a laboratory light microscope, used in the field with a battery-operated head lamp as an external ...
Fanello, C. I., Metzger, W. G., Magris, M., Gonçalves, J., Rodriguez, I., Bongard, Emily, Vivas, L., Gonçalves, J, Fanello, CI, Metzger, WG, Rodriguez, I, Vivas, L, Vivas-Martínez, S, Bongard, E, Magris, M, Vivas-Martínez, S.   +15 more
core   +1 more source

Dihydroartemisinin Alleviates the Symptoms of a Mouse Model of Systemic Lupus Erythematosus Through Regulating Splenic T/B-Cell Heterogeneity

Current Issues in Molecular Biology
Background: Systemic lupus erythematosus (SLE) is a complex autoimmune disease with significant therapeutic challenges. Recent studies suggest that dihydroartemisinin (DHA), a traditional Chinese medicine known for its anti-malarial properties, may be ...
Haihong Qin, Xiaohua Zhu, Xiao Liu, Yilun Wang, Jun Liang, Hao Wu, Jinfeng Wu   +6 more
doaj   +1 more source

Dihydroartemisinin Exerts Anti-Tumor Activity by Inducing Mitochondrion and Endoplasmic Reticulum Apoptosis and Autophagic Cell Death in Human Glioblastoma Cells

Frontiers in Cellular Neuroscience, 2017
Glioblastoma (GBM) is the most advanced and aggressive form of gliomas. Dihydroartemisinin (DHA) has been shown to exhibit anti-tumor activity in various cancer cells.
Chengbin Qu, Chengbin Qu, Chengbin Qu, Jun Ma, Jun Ma, Jun Ma, Xiaobai Liu, Xiaobai Liu, Xiaobai Liu, Yixue Xue, Yixue Xue, Yixue Xue, Jian Zheng, Jian Zheng, Jian Zheng, Libo Liu, Libo Liu, Libo Liu, Jing Liu, Jing Liu, Jing Liu, Zhen Li, Zhen Li, Zhen Li, Lei Zhang, Lei Zhang, Lei Zhang, Yunhui Liu, Yunhui Liu, Yunhui Liu   +29 more
doaj   +1 more source

ZIF-8 with encapsulated dihydroartemisinin in a drug delivery system for protection against Plasmodium berghei ANKA-induced experimental cerebral malaria in C57BL/6N mice

Microbiology Spectrum
Cerebral malaria (CM), primarily caused by Plasmodium falciparum, is the primary cause of malaria-related fatalities. CM treatment faces significant challenges due to limited therapeutic options and the emergence of antimalarial drug resistance ...
Yuting Li, Liu-Gen Li, Huiyin Zhu, Daiqian Zhu, Haimei Shi, Wei Wang, Jinyu Mo, Jianhai Yin, Tong-fei Li, Jian Li   +9 more
doaj   +1 more source