Results 71 to 80 of about 736 (160)
, 2020 Not AvailableIn this study, sterols in milk fat of cow, goat, bufalo and camel were analyzed for their variability across diferent season and species. A GC–MS-SIM (gas chromatography- mass spectrometry-single ion monitoring mode) method was developed for
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Chemical and Pharmaceutical Bulletin, 1989 Metabolism of 32-oxo-24,25-dihydrolanosterols (3 beta-hydroxylanost-8-en-32- al (4,delta 8-CHO) and 3 beta-hydroxylanost-7-en-32-al (5,delta 7-CHO)) was studied in a reconstituted system consisting of rat liver partially purified cytochrome P-450, which catalyzes lanosterol 14-demethylation (P-450(14DM)), and reduced nicotineamide adenine dinucleotide ...
SONODA, Yoshiko +2 more
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Reaction of 5α, and 5β, 3-keto-steroids with potassium superoxide
, 1981 4 pages, 2 schemes.-- Available online 9 March 2001.A regiospecific behaviour is observed in the reaction of 5α and 5β-keto-steroids with potassium superoxide; so the 5α- cholestan-3-one (I) gave the lactol II and the 3-keto-smilagenin (VII) gave the ...
Álvarez, Carlos Enrique +4 more
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Chemical and Pharmaceutical Bulletin, 1988 Metabolism of 32-hydroxylated 24, 25-dihydrolanosterols (1-3), including the intermediate of lanosterol and 24, 25-dihydrolanosterol (4, DHL) demethylation, were studied in a reconstituted system consisting of rat liver partially purified cytochrome P-450, which catalyzes lanosterol 14-demethylation (cytochrome P-45014DM), and reduced nicotinamide ...
SEKIGAWA, YOSHIO +2 more
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Chemical and Pharmaceutical Bulletin, 1992 The effects of 32-oxygenated lanosterol derivatives on 3-hydroxy-3-methylglutaryl coenzyme A (HMG-CoA) reductase activity and cholesterol biosynthesis from [24,25-3H]24,25-dihydrolanosterol were studied. Among the derivatives, 3 beta-hydroxylanost-7-en-32-oic acid was the most active in depressing HMG-CoA reductase activity (IC50: 0.7 microM) and ...
SONODA, Yoshiko +4 more
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Digitonide precipitable sterols: A reevaluation with special attention to lanosterol
, 1982 The ability of digitonin to precipitate lanosterol from prepared mixtures and biological sources was evaluated. Commercially available lanosterol was determined to be composed of about 60% lanosterol and 40% dihydrolanosterol.
Cenedella, Richard J. +1 more
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Processive kinetics in the three-step lanosterol 14α-demethylation reaction catalyzed by human cytochrome P450 51A1. [PDF]
J Biol Chem, 2023 McCarty KD +5 more
europepmc +1 more source
Studies on phytosterol biosynthesis: metabolism of 24,25-dihydrolanosterol and cholesterol in Ochromonas malhamensis [PDF]
Biochemical Journal, 1972 G H, Beastall, H H, Rees, T W, Goodwin
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Characterization of the cholesterol biosynthetic pathway in Dioscorea transversa. [PDF]
J Biol Chem, 2023 Salisbury LJ +5 more
europepmc +1 more source
Oxygenated sterols as inhibitors of enzymatic conversion of dihydrolanosterol into cholesterol
Oxygenated sterols as inhibitors of enzymatic conversion of dihydrolanosterol into cholesterol抄録
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