Results 121 to 130 of about 7,944 (148)

Interplay between store‐operated calcium entry and mitochondrial phosphate handling modulates force and fatigue during exercise

open access: yesThe Journal of Physiology, Volume 604, Issue 20, Page 8379-8427, 15 October 2026.
Abstract figure legend This study uses systems modelling to demonstrate a role of SOCE in sustained force generation during exercise. SOCE leads to two competing effects on contractile force in myofibres – increased cross‐bridge cycling due to elevated myoplasmic Ca2+$\text{Ca}^{2+}$ enhances force, whereas increased accumulation of myoplasmic ...
Emmet A. Francis   +3 more
wiley   +1 more source

Convenient synthesis of 4H-chromenyl-tetrahydro-2H-pyrancarboxylates and cleavage of chromone and pyran rings leading to 5-(2-hydroxybenzoyl)-2-(trifluoromethyl)-1,2-dihydropyridine-3-carboxylates

open access: yes, 2016
4H-Chromenyl-tetrahydro-2H-pyrancarboxylates 3a–k have been conveniently prepared by the reaction of 3-formylchromones 1a–k and ethyl 4,4,4-trifluoro-3-oxobutanoate 2a with good yields. Thus obtained 4H-chromenyl-tetrahydro-2H-pyrancarboxylates 3a–k were
Bhimapaka China Raju (736492)   +3 more
core   +1 more source

Taming photo-induced oxidation degradation of dihydropyridine drugs through cocrystallization

open access: yes, 2017
Cocrystallization was used as an effective approach to improve the photo-induced stability of dihydropyridine drugs. NFD·INA form I presents superior physicochemical properties compared with NFD itself.
Junjie Bao   +4 more
core   +1 more source

2026 Asia Pacific Heart Rhythm Society (APHRS) Guidelines (Part III) on Rate and Rhythm Control in Atrial Fibrillation

open access: yes
Journal of Arrhythmia, Volume 42, Issue 5, October 2026.
Minglong Chen   +19 more
wiley   +1 more source

In Hypertensive Urgency With Volume Overload—Intravenous Loop Diuretic may be Indicated

open access: yes
The Journal of Clinical Hypertension, Volume 28, Issue 10, October 2026.
Goran Koracevic, Milovan Stojanovic
wiley   +1 more source

Fluorenone and benzophenone 1,4-dihydropyridine derivatives with cardiodepressant activity

open access: yes, 1992
A series of fluorenone and benzophenone 1,4-dihydropyridine derivatives were prepared.
Valenti P.   +4 more
core  

Unexpected diastereotopic behaviour in the H-1 NMR spectrum of 1,4-dihydropyridine derivatives triggered by chiral and prochiral centres [PDF]

open access: yes, 2005
1,4-dihydropyridine derivatives constitute an important pharmacological group for the treatment of cardiovascular diseases. We have synthesised a series 4-(5'-nitro-2'-furyl)-1,4-dihydropyridine derivatives, which were characterised by H-1-NMR.
Núñez Vergara, Luis   +8 more
core  

Chemoenzymatic synthesis of enantiopure 1,4-dihydropyridine derivatives

open access: yes, 2003
Chirality is important for the activity of many biologically active compounds, since differences in biological properties of stereoisomers occur frequently.
Sobolev, A.
core  

Combination of dihydropyridine and non-dihydropyridine calcium antagonists in patients with arterial hypertension and coronary heart disease: efficacy and safety

open access: yesКардиоваскулярная терапия и профилактика, 2005
Aim. To study antihypertensive and anti-ischemic effects on structural and functional heart status, and assess treatment safety for combination of dihydropyridine and non-dihydropyridine calcium antagonists (CA). Material and methods.
B. G. Iskanderov   +4 more
doaj  

Heterogeneity of calcium channels from a purified dihydropyridine receptor preparation.

open access: yes, 1987
Dihydropyridine receptors were purified from rabbit skeletal muscle transverse tubule membranes and incorporated into planar lipid bilayers. Calcium channels from both the purified dihydropyridine receptor preparation and the intact transverse tubule ...
Talvenheimo, J. A.   +2 more
core   +1 more source

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