Results 111 to 120 of about 7,944 (148)
Synthesis of USP Grade [2,3,7‐13C3]‐Nicotinamide for Human Pharmacokinetic Studies
We prepared a 17.8‐g quantity of [2,3,7‐13C3]‐nicotinamide in five synthetic steps, with a 42% overall yield, and purified it to > 99% homogeneity, meeting USP standards for oral pharmaceutical dosing. This material is intended for tracking the movement and metabolism of nicotinamide through the human body.
Bruce G. Szczepankiewicz +10 more
wiley +1 more source
Perioperative Acute Hypertension – Role of Clevidipine Butyrate
Lakshmi N Kurnutala +3 more
doaj +1 more source
ABSTRACT Atrial fibrillation (AF) is closely associated with comorbidities and lifestyle factors that influence the development, progression, and outcomes. Here the focus is on guidelines for the systematic management of hypertension, heart failure, coronary and structural heart disease, diabetes, dyslipidemia, cerebrovascular disease, obesity, chronic
Eue‐Keun Choi +16 more
wiley +1 more source
Iron and Other Metal Ions in Human Health and Disease
Iron, copper, zinc, and calcium orchestrate cellular function through distinct yet cooperative mechanisms: redox‐active iron and copper cycle between oxidation states to act as Fenton catalysts and electron carriers in oxidative phosphorylation (OXPHOS); redox‐inert zinc serves as a structural component of zinc‐finger proteins and a catalytic cofactor ...
Xiaofeng Dai, Jitian Li
wiley +1 more source
Disentangling Molecular and Intrinsic Emission in Citric Acid–Urea Carbon Dots
Citric acid–urea thermal reactions under equimolar and urea‐rich conditions generate distinct fluorophore populations alongside carbon dots. Size‐exclusion chromatography reveals precursor‐dependent molecular species, whereas extended dialysis separates low‐molecular‐weight fluorophores from retained carbon dots. Despite the different synthetic regimes,
Chiara Olla +12 more
wiley +1 more source
Risk of Severe Hypoglycemia Associated With Concomitant Use of Sulfonylureas and Amiodarone
ABSTRACT Aims To evaluate whether initiation of amiodarone while receiving sulfonylurea is associated with an increased risk of severe hypoglycemia compared with the initiation of other antiarrhythmic agents (flecainide, sotalol, or propafenone) while receiving sulfonylurea. Materials and Methods We conducted a population‐based cohort study using South
Sungho Bea +5 more
wiley +1 more source
LERCANIDIPINE IN THE TREATMENT OF ARTERIAL HYPERTENSION
Aim: To search the literature assessing lercanidipine effectiveness, tolerability, and benefits in arterial hypertension (AH) treatment. Data sources: The literature search was performed using MEDLINE (1966 – September 2006), EMBASE Drugs and ...
C. Beckey, A. Lundy, N. Lutfi
doaj
Abstract Aims To evaluate the sustained impact of the Endocrine Hypertension Service on primary aldosteronism (PA) diagnosis and management over a subsequent 3‐year period. Background PA is a prevalent yet underdiagnosed cause of secondary hypertension, associated with increased cardiovascular, renal and metabolic risk. Limited awareness, resources and
Minn W. Chow +5 more
wiley +1 more source
Synthesis of a new dihydropyridine derivative containing a known vasodilator khellin
The synthesis and spasmolytic activity of a novel dihydropyridine derivative which contains a vasodilator furanochromone khellin at the 4th position of the dihydropyridine ring via the Hantzsch method from khellin-2-carboxaldehyde is ...
YILDIRIM, ENGİN +4 more
core +2 more sources
Catalyst-free electrochemical dearomatization of pyridine derivatives
We demonstrated herein an electrochemical dearomatizative alkylation of Katritzky salts, wherein Katritzky salts were harnessed as both radical acceptors and donors.
Kui Wang +8 more
doaj +1 more source

