Results 81 to 90 of about 19,079 (197)
Fixed‐Dose Combinations for Hypertension: Barriers to Use and Opportunities for Health Systems
ABSTRACT Background: Uncontrolled hypertension is a leading driver of heart disease, chronic kidney disease, heart failure, dementia, stroke, and pregnancy‐related complications. Fixed‐dose combinations (FDCs) are guideline‐endorsed first‐line therapies that improve blood pressure control by reducing pill burden, improving adherence, and targeting ...
Pranay Narang +4 more
wiley +1 more source
Perioperative Acute Hypertension – Role of Clevidipine Butyrate
Lakshmi N Kurnutala +3 more
doaj +1 more source
Antileishmanial and Antitoxoplasmal Activities of 1,4-dihydropyridines
We have synthesized 24 1,4-dihydropyridine compounds (1,4-DHPs) with different substituents at the aromatic ring by microwave-assisted one-pot Hantzsch multicomponent reaction and evaluated their in vitro activities against Toxoplasma gondii and Leishmania major. We have found that compound 9 ((±)-ethyl 2,7,7-trimethyl-4-(2-nitrophenyl)-5-oxo-1,4,5,6,7,
Thaís Oliveira +9 more
openaire +3 more sources
Abstract Heart failure with preserved ejection fraction (HFpEF) is associated with skeletal muscle dysfunction that contributes to exercise intolerance and disease progression. Altered Ca2+ homeostasis and increased oxidative stress have been proposed as mechanisms underlying muscle weakness in HFpEF; however, the effects of aerobic exercise on ...
Cielo Martínez Martínez +8 more
wiley +1 more source
Recent Approaches for the Synthesis of Pyridine and Quinoline Cores Present in Natural Products
An anthology of the most recent methods used to synthesize pyridines and quinolines found in natural products over the last decade. Pyridines, quinolines, and their derivatives represent a class of significant heterocyclic compounds that are prevalent in a multitude of natural products, including alkaloids found in plants, fungi, insects, marine ...
Carl Bowman +2 more
wiley +1 more source
A New Synthetic Approach to the Preparation of Indolo[3,2‐c]quinolines From Sulfonylalkyl Indoles
Functionalized indolo[3,2‐c]quinolines can be efficiently prepared from sulfonylalkyl indoles by a cascade process involving reduction, vinylogous aza‐Michael and aromatization reactions triggered by zinc powder in acetic acid at reflux. The reductive cyclization of sulfonylalkyl indoles obtained from 2‐(o‐nitroaryl)indoles, provides an efficient ...
Francesca Cecchini +3 more
wiley +1 more source
LERCANIDIPINE IN THE TREATMENT OF ARTERIAL HYPERTENSION
Aim: To search the literature assessing lercanidipine effectiveness, tolerability, and benefits in arterial hypertension (AH) treatment. Data sources: The literature search was performed using MEDLINE (1966 – September 2006), EMBASE Drugs and ...
C. Beckey, A. Lundy, N. Lutfi
doaj
Catalyst-free electrochemical dearomatization of pyridine derivatives
We demonstrated herein an electrochemical dearomatizative alkylation of Katritzky salts, wherein Katritzky salts were harnessed as both radical acceptors and donors.
Kui Wang +8 more
doaj +1 more source
Aim. To study antihypertensive and anti-ischemic effects on structural and functional heart status, and assess treatment safety for combination of dihydropyridine and non-dihydropyridine calcium antagonists (CA). Material and methods.
B. G. Iskanderov +4 more
doaj
Calcium Channel Blockers in Critical Care Medicine: Current Clinical Applications and Future Investigational Perspectives. [PDF]
Eraky AM +7 more
europepmc +1 more source

