Results 221 to 230 of about 3,167 (267)

K2CO3/TBAB, a composite of inorganic and organic salts, a novel and powerful media for regioselective Michael addition of dihydropyrimidinones to acrylic esters under without solvent conditions

Letters in Organic Chemistry, 2022
In this paper, a series of new dihydropyrimidinone derivatives using aza-Michael addition reaction were synthesized under solvent-free conditions. The reaction proceeded in the presence of K2CO3/TBAB, a media of inorganic base K2CO3 and organic ionic ...
Sevil Bonabi, G. Imanzadeh, Roghayyeh Asgharzadeh, Zahra Soltanzadeh   +3 more
semanticscholar   +1 more source

Synthesis of Dihydropyrimidinones Using Large Pore Zeolites

Catalysis Letters, 2011
A series of dihydropyrimidin-2(1H)-one (DHPM) belongs to one of the important class of therapeutic and pharmacological active compound, were synthesized through the multicomponent reactions (MCRs) of aldehydes, ethyl acetoacetate and urea, followed by the heterogeneous catalyzed Biginelli reaction.
Sunil R. Mistry, Rikesh S. Joshi, Suban K. Sahoo, Kalpana C. Maheria   +3 more
openaire   +1 more source

Novel selective biocatalytic deacetylation studies on dihydropyrimidinones

Journal of Molecular Catalysis B: Enzymatic, 2006
Five racemic ethyl 4-(3/4-acetoxyphenyl)-6-methyl-3,4-dihydropyrimidin-2-one-5-carboxylates have been synthesized by acetylation of corresponding hydroxy analogues, which in turn have been synthesized under microwave condition by multi-component Biginelli cyclocondensation of ethyl acetoacetate, urea and the corresponding hydroxybenzaldehydes in the ...
Prasad, Ashok K., Mukherjee, Chandrani, Singh, Sunil K., Brahma, Raju, Singh, Rajpal, Saxena, Rajendra K., Olsen, Carl Erik, Parmar, Virinder S.   +7 more
openaire   +2 more sources

Fe3O4@ATA‐Mo Complex as a Suitable and Reusable NanoCatalyst for Solvent‐Free Synthesis of Dihydropyrimidinones

ChemistrySelect
Fe3O4 nanoparticles were synthesized and functionalized by molybdenum aurintricarboxylic acid. Complex physicochemical characteristics of the catalyst were investigated by various methods such as infrared spectroscopy, X‐ray diffraction, scanning ...
Kazem Mohammad Jassim, Soheila Ghassamipour   +1 more
semanticscholar   +1 more source

Enhanced Catalytic Activity of Binuclear Oxidovanadium(IV) Bisbenzimidazole Linked Porphyrin Dimer for the Generation of Biologically Active 3,4-Dihydropyrimidinones and Their Corresponding Thiones.

Inorganic Chemistry
Binuclear vanadyl(IV) porphyrin (V2BP), where two vanadium(IV) porphyrin macrocycles are linked through benzimidazole units at the β-positions, has been prepared and characterized with various techniques, such as UV-vis, Fourier transform-infrared ...
S. Yadav, Akhil Patter, M. Sankar
semanticscholar   +1 more source

A chemo- and regio-selective three-component dihydropyrimidinone synthesis

Chemical Communications, 2007
A selective three-component coupling, involving co-condensation of aldehyde pairs with substituted ureas under Lewis acid catalysis, provides rapid access to highly functionalised dihydropyrimidinones; sulfamides react analogously.
Chris D, Bailey, Chris E, Houlden, Grégory L J, Bar, Guy C, Lloyd-Jones, Kevin I, Booker-Milburn   +4 more
openaire   +2 more sources

Targeting Breast Cancer: Novel Dihydropyrimidinones As Potent Eg5 Inhibitors.

Medicinal chemistry
INTRODUCTION Breast cancer remains a formidable health concern for women, necessitating the development of potent anticancer agents with improved safety profiles.
D. Nikam, Anurekha Jain, Shraddha Vetale, Ashwini Bhange, Shweta Jadhav   +4 more
semanticscholar   +1 more source

Biological activity of dihydropyrimidinone (DHPM) derivatives: A systematic review

European Journal of Medicinal Chemistry, 2018
Dihydropyrimidinones are heterocycles with a pyrimidine moiety in the ring nucleus, which, in recent decades, have aroused interest in medicinal chemistry due to alleged versatile biological activity. In this systematic review, we describe the currently published activities of dihydropyrimidinone derivatives.
Larizza Hellen Santana Matos, Flávia Teixeira Masson, Luiz Alberto Simeoni, Mauricio Homem-de-Mello   +3 more
openaire   +2 more sources

One‐Pot Construction of Dihydropyrimidinones in Ionic Liquids.

ChemInform, 2005
AbstractFor Abstract see ChemInform Abstract in Full Text.
Sushilkumar S. Bahekar, Sandip A. Kotharkar, Devanand B. Shinde   +2 more
openaire   +1 more source

Dihydropyrimidinones scaffold as a promising nucleus for synthetic profile and various therapeutic targets: A Review.

Current Organic Synthesis, 2020
BACKGROUND This review elaborates the updated synthetic and pharmacological approaches of a known group of dihydropyrimidinones/thiones from the multi-component reaction like Biginelli reaction was named Pietro Biginelli in 1891.
Shaik Khasimbi, F. Ali, Kiran Manda, Anjali Sharma, G. Chauhan, S. Wakode   +5 more
semanticscholar   +1 more source