Results 231 to 240 of about 3,167 (267)

Synthesis of 3,4‐Dihydropyrimidinones via Phase Transfer Catalysis

Journal of Heterocyclic Chemistry, 2013
3,4‐Dihydropyrimidinone and derivatives were synthesized by the one‐pot, three‐component Biginelli condensation of an aldehyde, β‐dicarbonyl compound and urea. Synthesis was carried out in aqueous sodium hydroxide using Aliquat‐336 as a phase transfer agent.
Younes Moussaoui, Ridha Ben Salem
openaire   +1 more source

Core–shell structured Fe3O4@SiO2-supported IL/[Mo6O19]: A novel and magnetically recoverable nanocatalyst for the preparation of biologically active dihydropyrimidinones

, 2020
The synthesis and catalytic application of a novel magnetic silica-nanomaterial-supported ionic liquid/hexamolybdate (Fe3O4@SiO2-IL/[Mo6O19]) are reported.
S. Kargar, D. Elhamifar, Ali Zarnegaryan
semanticscholar   +1 more source

Solvent-Free One-Pot Synthesis of Diverse Dihydropyrimidinones/Tetrahydropyrimidinones Using Biginelli Reaction Catalyzed by Fe3O4@C@OSO3H

Polycyclic aromatic compounds (Print), 2020
One-pot synthesis of 3,4-dihydropyrimidinone/thione and 3,4,5,6-tetrahydropyrimidinone/thione derivatives was successfully performed in high yields through the reaction of aromatic aldehyde, β-dicarbonyl, urea/thiourea using Fe3O4@C@OSO3H nano-catalyst ...
Seyedeh Fatemeh Taheri Hatkehlouei, B. Mirza, S. Soleimani‐Amiri   +2 more
semanticscholar   +1 more source

Magnetically reusable nanocatalysts in biginelli synthesis of dihydropyrimidinones (DHPMs)

, 2020
Molecules containing dihydropyrimidinone (DHPMs) structures are very important in pharmaceutical and medicinal chemistry due to their excellent biological activities application in synthesis of natural products. Biginelli condensation reaction between an
M. Kazemi
semanticscholar   +1 more source

ChemInform Abstract: Asymmetric Alkylations of N‐Acyl Dihydropyrimidinones.

ChemInform, 1991
AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
G. R. NEGRETE, J. P. KONOPELSKI
openaire   +1 more source

Chiral separation of pharmacologically active dihydropyrimidinones with carboxymethyl- β-cyclodextrin

ELECTROPHORESIS, 2001
We report on the chiral separation of pharmacologically active dihydropyrimidinones by capillary electrophoresis (CE) using carboxymethyl-beta-cyclodextrin as chiral selector. The influence of selector concentration, pH, and the addition of varying amounts of methanol is investigated. Out of 21 compounds investigated, 19 were resolved, 13 with baseline
O, Lecnik, M G, Schmid, C O, Kappe, G, Gübitz   +3 more
openaire   +2 more sources

Exploring DNA binding properties and biological activities of dihydropyrimidinones derivatives

Colloids and Surfaces B: Biointerfaces, 2013
The effects of substituent modifications for three dihydropyrimidinones derivatives on DNA binding properties were investigated using viscometry in combination with spectroscopy and isothermal titration calorimetry (ITC). The results indicated that substitution in 4 rd position of benzene ring has significant effects on DNA binding mode, affinity and ...
Gongke, Wang, Changling, Yan, Yan, Lu
openaire   +2 more sources

Synthesis and Antioxidant Evaluation of Dihydropyrimidinone Integrated Pyrazoles

Letters in Organic Chemistry, 2019
: A series of novel ethyl 6-[2-(3-aryl-1-phenyl-1H-pyrazol-4-yl)vinyl]-2-oxo-4-phenyl- 1,2,3,4-tetrahydropyrimidine-5-carboxylates (9a-9d) has been synthesized by adopting a multistep synthetic strategy. The structure of the targets was confirmed on the basis of physical and spectral techniques.
Krishnaraj Padmavathy, Peramasivan Sutha, Kannan G. Krishnan, Chandran U. Kumar, Shunmugam Iniyaval, Chennan Ramalingan   +5 more
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Biological activities of dihydropyrimidinones

2023
Aneeza Noor, Wajahat Mushtaq, Insha Qadir, Mubashir Hussain Masoodi   +3 more
openaire   +1 more source

SYNTHESIS AND BIOACTIVITY OF DIHYDROPYRIMIDINONE (DHPM)DERIVATIVES.

European Chemical Bulletin
Dihydropyrimidinones are heterocycles with a pyrimidine moiety in the ring nucleus, which, in recent decades, have aroused interest in medicinal chemistry due to alleged versatile biological activity. Pyrimidine is one of these heterocyclic compounds having a wide range of biological activity. Pyrimidines are the fundamental structures of nucleic acids,
Ganesh L. Kirdat, Onkar S. Dhindale, Tushar M. Dalimbkar, Mr. Nikhil A. Mandlik   +3 more
openaire   +1 more source