Results 1 to 10 of about 19,826 (185)
15-Hydroxyprostaglandin Dehydrogenase Inhibitor Restores Endothelial Function Under Dihydrotestosterone-Induced Stress in Human Dermal Microvascular Endothelial Cells [PDF]
MoleculesAndrogenetic alopecia (AGA) is closely associated with oxidative stress and vascular dysfunction, which disrupt nutrient delivery to hair follicles and promote follicle miniaturization.
Mujun Kim +6 more
doaj +2 more sources
Behavioral Alterations in Male Zebrafish After Administration of Androgen Receptor Blockers and an Activator [PDF]
BiologyAndrogen receptor (AR) signaling is crucial for mediating male-typical behaviors across vertebrates. Enzalutamide (ENZ) and apalutamide (APA) are two second-generation androgen receptor inhibitors (SGARIs) that have been primarily used in the treatment ...
Ching-Yu Huang +6 more
doaj +2 more sources
Hemp Seed-Derived Exosomes Protect Against Dihydrotestosterone-Induced Chicken Feather Growth Inhibition [PDF]
PharmaceuticalsBackground/Objectives: Androgenetic alopecia suppresses hair follicle growth. This occurs via dihydrotestosterone (DHT), which inhibits key molecular pathways such as Wnt/β-catenin and Sonic Hedgehog (SHH) signaling.
Hwapyung Kim +3 more
doaj +2 more sources
COVID-19 and androgenic status: testosterone or dihydrotestosterone have a pivotal role? [PDF]
Journal of Men's Health, 2023 The aim of our study is analysis of the androgenic status including testosterone (T) and dihydrotestosterone (DHT) in men hospitalized with coronavirus disease 2019 (COVID-19) and them relationship with the course of the disease. This is a monocentric
Kamalov Аrmais +12 more
doaj +1 more source
A role for steroid 5 alpha-reductase 1 in vascular remodeling during endometrial decidualization
Frontiers in Endocrinology, 2022 Decidualization is the hormone-dependent process of endometrial remodeling that is essential for fertility and reproductive health. It is characterized by dynamic changes in the endometrial stromal compartment including differentiation of fibroblasts ...
Isaac W. Shaw +8 more
doaj +1 more source
Activation of Hair Cell Growth Factors by Linoleic Acid in Malva verticillata Seed
Molecules, 2021 Hair loss by excessive stress from work and lifestyle changes has become a growing concern, particularly among young individuals. However, most drugs for alopecia impose a plethora of side effects.
Hwa Sun Ryu +6 more
doaj +1 more source
Diagnostics, 2023 The aim of this systematic review is to provide a comprehensive overview of the role of fluoro-5α-dihydrotestosterone ([18F]-FDHT) for the in vivo imaging of androgen receptors (AR) through positron emission tomography (PET) in metastatic breast (mBC ...
Luca Filippi +3 more
doaj +1 more source
Frontiers in Pharmacology, 2020 Dihydrotestosterone (DHT) is the most potent androgen that regulates hair cycling. Hair cycling involves cross-talk between the androgen and Wnt/β-catenin pathways.
Xianyan Chen +8 more
doaj +1 more source
Frontiers in Pharmacology, 2021 The screening of hair follicles, dermal papilla cells, and keratinocytes through in vitro, in vivo, and histology has previously been reported to combat alopecia.
Jawaria Iltaf +9 more
doaj +1 more source
Life, 2023 Androgenic alopecia (AGA) is a dermatological disease with psychosocial consequences for those who experience hair loss. AGA is linked to an increase in androgen levels caused by an excess of dihydrotestosterone in blood capillaries produced from ...
Sibhghatulla Shaikh +6 more
doaj +1 more source