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In-silico investigation reveals microbial metabolic biomarkers and their regulatory roles in hormone sensitive cancers. [PDF]
Anbarasu S +3 more
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Latrophilin-1 and latrophilin-2 as androgen receptor-responsive G protein-coupled receptors promote bladder cancer progression. [PDF]
Goto T, Akai T, Teramoto Y, Miyamoto H.
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[Radioimmunoassay for plasma dihydrotestosterone (1)].
M, Hosaka +4 more
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Fluoroimmunoassay of 5α-dihydrotestosterone
Journal of Steroid Biochemistry, 1981Abstract A method for the fluoroimmunoassay of 5α-dihydrotestosterone is described, in which 4-methylumbelli-feryl-3-acetic acid is used as fluorogenic label. 3β-amino-5α-dihydrotestosterone was conjugated to the lone terminal carboxyl group of a poly- l -lysine carrier which was fluorescently labelled with 25 molecules of the fluorogenic compound ...
D, Exley, G I, Ekeke
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Dihydrotestosterone and cancer risk
Current Opinion in Endocrinology, Diabetes & Obesity, 2018Purpose of reviewAndrogens have been implicated in prostate growth; however, the role of androgens in prostate cancer development is not clear. Furthermore, studies suggest a role for androgens in female-hormone-dependent cancers and common nonhormone dependent cancers.
Yi X, Chan, Bu B, Yeap
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Clinical biochemistry of dihydrotestosterone
Annals of Clinical Biochemistry: International Journal of Laboratory Medicine, 2013Dihydrotestosterone (DHT) is the most potent natural androgen in humans. There has been an increasing interest in this androgen and its role in the development of primary and secondary sexual characteristics as well as its potential roles in diseases ranging from prostate and breast cancer to Alzheimer's disease. Despite the range of pathologies shown
Paula M, Marchetti, Julian H, Barth
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Structure of 5β-dihydrotestosterone
Acta Crystallographica Section C Crystal Structure Communications, 199017 beta-Hydroxy-5 beta-androstan-3-one, C19H30O2, Mr = 290.45, orthorhombic, P2(1)2(1)2(1), a = 11.7821 (6), b = 21.2184 (8), c = 6.5322 (2) A, V = 1633.0 (2) A3, Z = 4, D chi = 1.181 Mg m-3, lambda(Cu K alpha) = 1.54178 A, mu = 0.58 mm-1, F(000) = 640, T = 293 K, R = 0.033 for 1849 unique observed reflections.
A W, Roszak, P W, Codding
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