Results 151 to 160 of about 19,826 (185)

Dihydrotestosterone in Human Peripheral Plasma

The Journal of Clinical Endocrinology & Metabolism, 1970
ABSTRACT A method is described for the estimation of dihydrotestosterone (5α-androstan- 17β-ol-3-one) in human peripheral plasma. An aliquot of 5–10 ml of plasma with 3H indicator is extracted with solvent and chromatographed on low residue, methanol washed paper in the Bush B-3 system for 2–3 hr.
T, Ito, R, Horton
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A new dihydrotestosterone-forming index (DHTi)

Journal of Steroid Biochemistry, 1985
A new index (DHTi) for the net formation of dihydrotestosterone (DHT) in a specific tissue is presented. This index is based on the main metabolic pathways forming DHT as well as on the main enzymatic activities removing DHT from the tissue. In the rat prostate, the DHTi is different in the various prostatic lobes.
P I, Lundmo, A, Sunde, K J, Tveter
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Percutaneous dihydrotestosterone treatment

1998
Various forms of androgen replacement therapy are readily available for the treatment of hypogonadism in men (Cantril et al. 1984). The commonly used long-acting, injected, testosterone esters produce wide variations of serum androgen concentrations with high levels soon after the injection and subnormal levels after 15 days (Snyder et al. 1980).
Gilbert Schaison, Béatrice Couzinet
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DIHYDROTESTOSTERONE IN HUMAN SPERMATIC VENOUS PLASMA

Acta Endocrinologica, 1974
ABSTRACT Testosterone (T) and 5α-dihydrotestosterone (DHT) concentrations in spermatic and peripheral venous blood obtained from six men have been measured by radioimmunoassay and competitive protein binding assay respectively. The concentrations (mean ± sd) of DHT in the spermatic vein (0.64 ± 0.33 μg/100 ml) were higher than that found in the
PAZZAGLI, MARIO, D. Borrelli, FORTI, GIANNI, SERIO, MARIO   +3 more
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DIHYDROTESTOSTERONE IN HUMAN OVARIAN VENOUS PLASMA

European Journal of Endocrinology, 1976
Androstenedione (delta), oestradiol-17beta (Oe2), 5alpha-dihydrotestosterone (DHT), progesterone (P) and testosterone (T) concentrations have been measured by radioimmunoassay in ovarian and peripheral venous blood from 15 women in the luteal phase of the cycle.
E. Calabresi, G. Fiorelli, FORTI, GIANNI, G. Lombardi, PAZZAGLI, MARIO, E. Dell'Acqua, SERIO, MARIO   +6 more
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5α-Dihydrotestosterone sulphate and cortisone reductase

Biochimica et Biophysica Acta (BBA) - Lipids and Lipid Metabolism, 1972
Abstract 5α-Dihydrotestosterone sulphate (3-oxo-5a-androstan-17β-yl sulphate) was shown to be a much worse substrate than 5α-dihydrotestosterone (17β-hydroxy-5α-androstan-3-one) for cortisone reductase (EC 1.1.1.53). This contrasted with a previous finding that pregnenolone (3β-hydroxy-5-pregnen-20-one) and pregnenolone sulphate (20-oxo-5-pregnen-3β ...
W, Gibb, J, Jeffery
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The backdoor pathway to dihydrotestosterone

Trends in Endocrinology & Metabolism, 2004
Dihydrotestosterone (DHT) is the androgen responsible for formation of the male external genitalia during embryogenesis and for most androgen-mediated events at male puberty. In most circumstances, testosterone (T) derived from the testis is converted to DHT by 5alpha-reductase type 2 in genital skin and prostate. By contrast, the testes of pouch young
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Cardiovascular effects of dihydrotestosterone in rats

Legal Medicine, 1999
We conducted a study to evaluate the cardiovascular effects of 5 alpha-dihydrotestosterone (DHT), including the supplementary respiratory effects, using normal and obese groups of Wistar castrated male rats, and the association of the hormonal effect with sudden unexplained nocturnal death syndrome (SUNDS).
K, Tsunoda, Y, Yamaguchi, T, Taguchi, K, Doge, Y, Kato, A, Sato, S, Keizo   +6 more
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Simultaneous radio immunoassay of testosterone and dihydrotestosterone

Steroids, 1974
Abstract A radioimmunoassay, which simultaneously measures both testosterone (T) and dihydrotestosterone (DHT) in the same serum sample, is presented. Celite column chromatography is employed to separate T from DHT, and these two steroids from other potentially cross-reacting and interfering steroids.
J M, Barberia, I H, Thorneycroft
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Dihydrotestosterone and 5α-Reductase

2003
In man, 4–8 of testosterone (T) undergoes 5a-reduction, resulting in the formation of the potent androgen dihydrotestosterone (DHT). DHT plays a crucial role in the formation of the external male genitalia and prostate during fetal life. In the adult, however, DHT is associated with a variety of chronic conditions, including benign prostatic ...
Paul R. Sutton, John K. Amory, Richard V. Clark   +2 more
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