Results 11 to 20 of about 19,826 (185)
Sex Hormones Attenuate Pro-Inflammatory Gene Expression in Nucleus Pulposus and Annulus Fibrosus Cells in a Cell-Type Specific Manner. [PDF]
JOR SpineMethodological overview of primary bovine NP and AF cell culture. Pro‐ and anti‐inflammatory gene and protein expression analyses were performed after 24 h of pro‐inflammatory stimulus, followed by 3 days of cotreating cells with sex hormones in addition to pro‐inflammatory cytokines.
Hutchinson JL, Leung AE, Séguin CA.
europepmc +2 more sources
Cell Reports, 2018 Castration-resistant prostate cancer (CRPC) requires tumors to engage metabolic mechanisms that allow sustained testosterone and/or dihydrotestosterone to stimulate progression.
Hyun-Kyung Ko +7 more
doaj +1 more source
Applied Sciences, 2022 Benign prostatic hyperplasia (BPH) is one of the most common diseases in elderly men and causes lower urinary tract symptoms due to excessive proliferation of prostate stromal and epithelial cells.
Subin Oh +6 more
doaj +1 more source
CPT1A Supports Castration-Resistant Prostate Cancer in Androgen-Deprived Conditions
Cells, 2019 Prostate cancer (PCa) is the most common cancer in men, and the global burden of the disease is rising. The majority of PCa deaths are due to metastasis that are highly resistant to current hormonal treatments; this state is called castration-resistant ...
Molishree Joshi +6 more
doaj +1 more source
The spectrum of prostate specific antigen values in organ-confined prostate cancer [PDF]
Medicinski Podmladak, 2016 Prostate specific antigen (PSA) concentration in localized serum of the prostate cancer (PCa) in patients, depends of numerous factors related to tumor, prostate and the patient.
Pejčić Tomislav, Dimitrijević Vladan
doaj +1 more source
Dihydrotestosterone in Amyotrophic lateral sclerosis—The missing link?
Brain and Behavior, 2020 Objective Testosterone has been postulated to be involved in ALS causation. Materials and methods CSF levels of free testosterone and dihydrotestosterone were measured in 13 ALS patients [7 males, 6 females] and 22 controls [12 males, 10 females ...
Nishit Sawal +3 more
doaj +1 more source
Frontiers in Endocrinology, 2020 Background: Hepatocellular carcinoma (HCC) is a male-predominant cancer. However, the relationship between 5α-dihydrotestosterone (DHT), the active form of testosterone, and HCC risk has not been established yet.Methods: We performed a serum ...
Lichun Wang +8 more
doaj +1 more source
Laboratory Animal Research, 2018 Benign prostate hyperplasia (BPH) is a male reproductive disease that has gained increasing importance in recent years. The present study investigated whether Pycnogenol® (PYC), a standardized French maritime pine bark extract, could prevent BPH induced ...
Je-Won Ko +6 more
doaj +1 more source
Euodia rutaecarpa fruit attenuates testosterone-induced benign prostatic hyperplasia in rats by inhibiting 5α-reductase activity and androgen receptor signaling pathway [PDF]
Journal of Men's HealthIn this study, effect of an ethanol extract of Euodia rutaecarpa fruit (EER), known to have various pharmacological effects, on benign prostatic hyperplasia (BPH) was evaluated.
Yung Hyun Choi
doaj +1 more source
Amelioration of Benign Prostatic Hyperplasia by Costunolide and Dehydrocostus Lactone in Wistar Rats
The World Journal of Men's Health, 2021 Purpose: Sesquiterpene lactones, which are found in plants of the Asteraceae family, contain costunolide (CO) and dehydrocostus lactone (DCL) as indicator material.
Dohyun Choi +5 more
doaj +1 more source