Results 91 to 100 of about 24,273 (376)
Advanced Science, EarlyView.The immunocompetent Intestine‐on‐a‐Chip (IoC) is developed using melt electrowritten (MEW) half‐pipes. Intestinal epithelial cell (IEC) culture is optimized in the MEW‐based IoC, followed by co‐culture with monocyte‐derived dendritic cells (moDCs) and T cells in 3D hydrogels.
Robine Janssen +10 more
wiley +1 more source
Photoelectrochemical properties of melanin [PDF]
, 2007 Melanin is to the animal kingdom like chlorophyll to the vegetal kingdom(1). Melanin collects energy from lower-energy radiation sources, kicks electrons into excited states, initiating a process that would end up producing chemical energy, similar to ...
Arturo Solis +2 more
core +1 more source
Diglycerides of Natural Phenols and Organic Acids for Enhanced Biological Activities
Asian Journal of Organic Chemistry, EarlyView.Diglycerides of natural organic acids and phenols were synthesized regio‐selectively. Diglycerides are structurally similar to cell membranes and are expected to exhibit cell affinity and permeability. The flexible glycerol linkers allow the diglycerides to exhibit not only the physiological activities of each constituent organic acid but also the ...
Jisu Hong +10 more
wiley +1 more source
Pteridines, 2006 We examined the role of endogenous tetrahydrobiopterin (BH4) on L-tyrosine-induced increase in cytosolic Ca: concentration ([Ca2+],) in the ß-cell line, HIT-T15.
Ishii Masakazu +3 more
doaj +1 more source
Hypothesis:soluble Aβ oligomers in association with redox-active metal ions are the optimal generators of reactive oxygen species in Alzheimer's disease [PDF]
, 2010 Considerable evidence points to oxidative stress in the brain as an important event in the early stages of Alzheimer's disease (AD). The transition metal ions of Cu, Fe, and Zn are all enriched in the amyloid cores of senile plaques in AD.
Allsop, David +2 more
core +5 more sources
Angewandte Chemie International Edition, Accepted Article.Cryptococcus species are major fungal pathogens responsible for life‐threatening infections in approximately a million individuals globally each year, with alarmingly high mortality rates. These fungi are distinguished by a distinctive cell wall architecture further reinforced by two virulence‐associated layers, melanin and capsule, rendering them ...
Ankur Ankur +11 more
wiley +1 more source
Journal of Pharmacological Sciences, 2012 l-Dihydroxyphenylalanine (l-DOPA) is considered the gold standard for the treatment of Parkinson’s disease (PD). However, long-term administration of l-DOPA can induce abnormal side effects.
Masatoshi Inden +6 more
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PET Studies of Cerebral Levodopa Metabolism: A Review of Clinical Findings and Modeling Approaches [PDF]
, 2009 [18F]Fluoro-3,4-dihydroxyphenyl-l-alanine (FDOPA) was one of the first successful tracers for molecular imaging by positron emission tomography (PET), and has proven immensely valuable for studies of Parkinson’s disease.
Cumming, Paul, Kumakura, Yoshitaka
core +1 more source
Angewandte Chemie International Edition, Accepted Article.Supramolecular chemistry has advanced rapidly, with scientists using fundamental understanding to generate function from simple building blocks. However, synthetic systems are still in their infancy when compared to biology. The increasing use of peptides in supramolecular structures provides a clear roadmap to more complex function; introducing chiral,
Ben E. Barber +3 more
wiley +1 more source
Growth response of Heterobranchus longifilis (Valenciennes, 1840) fingerlings fed raw and boiled Mucuna cochinchinensis seed meal [PDF]
, 2004 Feeding trial was conducted in static water to assess the growth of H. longifilis fingerlings fed different I inclusion levels of mucuna seed meal (MSM).
Osuigwe, D. I.
core