Results 21 to 30 of about 9,926 (263)
Management of L-Dopa Overdose in the Competitive Inhibition State [Expression of Concern]
Drug, Healthcare and Patient Safety, 2020 Hinz M, Stein A, Cole T. Drug Healthc Patient Saf. 2014;6:93–99. The Editor-in-Chief and Publisher of Drug, Healthcare and Patient Safety wish to issue an Expression of Concern for the published article.
Hinz M, Stein A, Cole T
doaj
Journal of the Mechanical Behavior of Materials, 2021 Dopamine is considered an important molecule that plays several essential roles in the human body, and herein lies the key to this paper on the electronic and optical properties of dopamine and its derivatives, such as quinone and L ...
Jabbar Mohammed L.
doaj +1 more source
Management of L-Dopa Overdose in the Competitive Inhibition State [Retraction]
Drug, Healthcare and Patient Safety, 2020 Hinz M, Stein A, Cole T. Drug Healthc Patient Saf. 2014;6:93— 99. The Editor-in-chief and Publisher of Drug, Healthcare and Patient Safety wish to retract the published article.
Hinz M, Stein A, Cole T
doaj
Анналы клинической и экспериментальной неврологии, 2021 Levodopa (3-hydroxy-L-tyrosine, the levorotatory isomerof 3,4-dihydroxyphenylalanine) is a biological precursor of the neurotransmitter dopamine and has been the "gold standard" in the treatment of Parkinsons disease for over 50 years. The widespread use
Denis А. Abaimov +6 more
doaj +1 more source
Visualization of Intracellular Tyrosinase Activity in vitro
Bio-Protocol, 2016 Melanocytes produce the melanin pigments in melanosomes and these organelles protect the skin against harmful ultraviolet rays. Tyrosinase is the key cuproenzyme which initiates the pigment synthesis using its substrate amino acid tyrosine or L-DOPA (L-3,
Riddhi Jani, Sudeshna Nag, Subba Setty
doaj +1 more source
Mussel-Inspired Catechol-Functionalized Hydrogels and Their Medical Applications
Molecules, 2019 Mussel adhesive proteins (MAPs) have a unique ability to firmly adhere to different surfaces in aqueous environments via the special amino acid, 3,4-dihydroxyphenylalanine (DOPA).
Wei-Yan Quan +7 more
doaj +1 more source
l-DOPA and Its Receptor GPR143: Implications for Pathogenesis and Therapy in Parkinson’s Disease
Frontiers in Pharmacology, 2019 l-3,4-Dihydroxyphenylalanine (l-DOPA) is the most effective therapeutic agent for Parkinson’s disease (PD). l-DOPA is traditionally believed to be an inert amino acid that exerts actions and effectiveness in PD through its conversion to dopamine.
Yoshio Goshima +4 more
doaj +1 more source
Biological Properties and Applications of Betalains
Molecules, 2021 Betalains are water-soluble pigments present in vacuoles of plants of the order Caryophyllales and in mushrooms of the genera Amanita, Hygrocybe and Hygrophorus. Betalamic acid is a constituent of all betalains.
Izabela Sadowska-Bartosz +1 more
doaj +1 more source
In silico and in vitro exploration of a tyrosinase for biocatalytic production of catechols
FEBS Open Bio, EarlyView.Tyrosinase from Ralstonia pseudosolanacearum is a promising biocatalyst for producing valuable catechols from monophenol substrates. This tyrosinase is uniquely suited to this due to its high monophenolase : diphenolase ratio. We combined in silico docking and in vivo kinetic characterisation of this tyrosinase with 11 industrially relevant monophenols,
James Britton +6 more
wiley +1 more source
CSF Monoamine Metabolites and Cognitive Trajectory in Early Parkinson's Disease
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Background Imaging and postmortem studies indicate that abnormalities in monoaminergic neurotransmission contribute to cognitive impairment in Parkinson's disease (PD). However, it remains uncertain if cerebrospinal fluid (CSF) monoamine metabolites can serve as biomarkers of cognitive decline in early PD.
Jing‐Yu Shao +7 more
wiley +1 more source