Results 1 to 10 of about 45,565 (167)
Crop Journal, 2018 Faba bean (Vicia faba L.) has been identified as a rich source of l-DOPA, which is used in treating Parkinson's disease. Biosynthesis and accumulation of active substances such as l-DOPA in plant tissues may interact with growing conditions and ...
Masoud Hashemi +2 more
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Frontiers in Cellular and Infection Microbiology, 2022 BackgroundParkinson’s disease (PD) is a common neurodegenerative disorder, accompanied by motor deficits as well as gastrointestinal dysfunctions.
Can Cui +5 more
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Catecholamine Derivatives as Novel Crosslinkers for the Synthesis of Versatile Biopolymers
Journal of Functional Biomaterials, 2023 Catecholamine metabolites are not only involved in primary metabolism, but also in secondary metabolism, serving a diverse array of physiologically and biochemically important functions. Melanin, which originates from dopa and dopamine, found in the hair,
Manickam Sugumaran, Jason J. Evans
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A promising material for bone repair: PMMA bone cement modified by dopamine-coated strontium-doped calcium polyphosphate particles [PDF]
Royal Society Open Science, 2019 Polymethyl methacrylate (PMMA) bone cement has been widely used in clinics as bone repair materials for its excellent mechanical properties and good injection properties. However, it also has defects such as poor biological performance, high temperature,
Xing Liu +7 more
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Reactions of DOPA (3,4-dihydroxyphenylalanine) decarboxylase with DOPA [PDF]
Biochemical Journal, 1979 The study of DOPA (3,4-dihydroxyphenylalanine) decarboxylase by steady-state methods is difficult because multiple reactions occur. The reaction with DOPA was studied at enzyme concentrations between 20 and 50 micrometer by direct observation of the bound coenzyme by using stopped-flow and conventional spectrophotometry. Four processes were observed on
A. Minelli +3 more
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Pyrylium based derivatization imaging mass spectrometer revealed the localization of L-DOPA.
PLoS ONE, 2022 Simultaneous imaging of l-dihydroxyphenylalanine (l-DOPA), dopamine (DA) and norepinephrine (NE) in the catecholamine metabolic pathway is particularly useful because l-DOPA is a neurophysiologically important metabolic intermediate.
Shu Taira +6 more
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D-DOPA Is a Potent, Orally Bioavailable, Allosteric Inhibitor of Glutamate Carboxypeptidase II
Pharmaceutics, 2022 Glutamate carboxypeptidase-II (GCPII) is a zinc-dependent metalloenzyme implicated in numerous neurological disorders. The pharmacophoric requirements of active-site GCPII inhibitors makes them highly charged, manifesting poor pharmacokinetic (PK ...
Sadakatali S. Gori +10 more
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Simultaneous Determination of Levodopa and Carbidopa from Fava Bean, Green Peas and Green Beans by High Performance Liquid Gas Chromatography [PDF]
Journal of Clinical and Diagnostic Research, 2013 Introduction: According to many studies, sprouted fava beans are a rich source of levo-dihydroxy phenylalanine (L-dopa) the precursor of dopamine, and they are now being investigated for use in the management of Parkinson’s disease.
Mohseni Mehran S.M., Golshani B.
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Neurobiology of Disease, 2021 L-dopa is the most effective drug used to date for management of Parkinson's disease symptoms. Unfortunately, long-term administration of L-dopa often results in development of motor disorders, including dyskinesias.
Agustina Zorgniotti +3 more
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Materials & Design, 2020 Combining biodegradable materials with bioactive factors for skin wound healing has been receiving significant attention. This study was inspired by the adhesion mechanism of a marine organism, the mussel. 3,4-Dihydroxyphenylalanine (DOPA) was introduced
Jing Zhan +4 more
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