Results 21 to 30 of about 101,529 (354)
This study aimed to investigate the effects of levodopa (L-dopa), p-coumaric acid, and combinations in the neuroblastoma (N1E-115) cell. L-dopa and L-dopa plus p-coumaric acid group caused oxidative stress by increasing 12.5 and 3.7-fold in superoxide ...
Nebiye Pelin Turker, Elvan Bakar
doaj +1 more source
Dopa-responsive dystonia [PDF]
Doparesponsiv dystoni er en gruppe sykdommer som gir endrede nivåer av nevrotransmittere. Dette kan behandles med god effekt. Økt innsikt i patofysiologiske årsaksforhold har bedret forståelsen av sykdommene.Artikkelen bygger på 39 artikler fra et systematisk søk i databasen Medline, to nettsteder og en lærebok.Doparesponsiv dystoni debuterer som ...
Hans, Randby +4 more
openaire +2 more sources
In the title molecular salt, C9H12NO4+·Br−·C9H11NO4, one of the dopa molecules is in the cationic form in which the α-amino group is protonated and the α-carboxylic acid group is uncharged, while the second dopa molecule is in the zwitterion form. The Br−
Perumal Kathiravan +5 more
doaj +1 more source
In 10 patients with Parkinsonism, treatment with L-dopa was associated with a rise in the skin conductance level and its fluctuations, an increased electromyographic activity in the frontalis muscle, and with faster reaction times. The change of skin conductance in response to a loud noise also increased and its habituation to the repetition of the ...
T B, Horvath, R A, Meares
openaire +2 more sources
6R-L-erythro-5,6,7,8-Tetrahydrobiopterin and Dopamine Release
We previously reported that intracerebroventricular administration of 6R-L-erythro-5,6,7,8-tetrahydrobiopterin (6R-BJL), a cofactor for aromatic amino acid hydroxylases and nitric oxide synthase, induces an increase in DOPA levels (as an index of DA ...
Miwa Soichi, Koshimura Kunio
doaj +1 more source
GABA storage and release in the medial globus pallidus in L-DOPA-induced dyskinesia priming
Levo-dihydroxyphenylalanine (L-DOPA) is the most effective treatment for Parkinson's disease; however, most patients develop uncontrollable abnormal involuntary movements known as L-DOPA-induced dyskinesia.
Haruo Nishijima +10 more
doaj +1 more source
Secretion of Dopa in Phaeochromocytoma [PDF]
In a series of 11 cases with phaeochromocytoma, two patients were found in whom the tumour secreted dopa in addition to dopamine, noradrenaline, and adrenaline. These two patients were normotensive in spite of high plasma and urinary levels of noradrenaline and adrenaline.
W J, Louis +3 more
openaire +2 more sources
Metabolic engineering of Escherichia coli BL21 (DE3) for de novo production of l-DOPA from d-glucose
BackgroundProduction of l-tyrosine is gaining grounds as the market size of 3,4-dihydroxyphenyl-l-alanine (l-DOPA) is expected to increase due to increasing cases of Parkinson’s disease a neurodegenerative disease.
E. Fordjour +4 more
semanticscholar +1 more source
The Digital Observatory for Protected Areas (DOPA) Explorer 1.0 [PDF]
The Digital Observatory for Protected Areas (DOPA) has been developed to support the European Union’s efforts in strengthening our capacity to mobilize and use biodiversity data, information and forecasts so that they are readily accessible to ...
Martinez-Lopez, Javier +6 more
core +1 more source
The pharmacological manipulation of neuroinflammation appears to be a promising strategy to alleviate l-DOPA-induced dyskinesia (LID) in Parkinson’s disease (PD).
Patrick Pierre Michel (2019922) +5 more
core +1 more source

