Results 21 to 30 of about 101,529 (354)

Effects of L-dopa and p-coumaric acid combination on oxidative stress, DNA damage, and mitochondrial apoptosis in neuroblastoma cells

open access: yesBangladesh Journal of Pharmacology, 2023
This study aimed to investigate the effects of levodopa (L-dopa), p-coumaric acid, and combinations in the neuroblastoma (N1E-115) cell. L-dopa and L-dopa plus p-coumaric acid group caused oxidative stress by increasing 12.5 and 3.7-fold in superoxide ...
Nebiye Pelin Turker, Elvan Bakar
doaj   +1 more source

Dopa-responsive dystonia [PDF]

open access: yesTidsskrift for Den norske legeforening, 2018
Doparesponsiv dystoni er en gruppe sykdommer som gir endrede nivåer av nevrotransmittere. Dette kan behandles med god effekt. Økt innsikt i patofysiologiske årsaksforhold har bedret forståelsen av sykdommene.Artikkelen bygger på 39 artikler fra et systematisk søk i databasen Medline, to nettsteder og en lærebok.Doparesponsiv dystoni debuterer som ...
Hans, Randby   +4 more
openaire   +2 more sources

Crystal structure and Hirshfeld surface analysis of 1-carboxy-2-(3,4-dihydroxyphenyl)ethan-1-aminium bromide 2-ammonio-3-(3,4-dihydroxyphenyl)propanoate

open access: yesActa Crystallographica Section E: Crystallographic Communications, 2016
In the title molecular salt, C9H12NO4+·Br−·C9H11NO4, one of the dopa molecules is in the cationic form in which the α-amino group is protonated and the α-carboxylic acid group is uncharged, while the second dopa molecule is in the zwitterion form. The Br−
Perumal Kathiravan   +5 more
doaj   +1 more source

L-dopa and arousal [PDF]

open access: yesJournal of Neurology, Neurosurgery & Psychiatry, 1974
In 10 patients with Parkinsonism, treatment with L-dopa was associated with a rise in the skin conductance level and its fluctuations, an increased electromyographic activity in the frontalis muscle, and with faster reaction times. The change of skin conductance in response to a loud noise also increased and its habituation to the repetition of the ...
T B, Horvath, R A, Meares
openaire   +2 more sources

6R-L-erythro-5,6,7,8-Tetrahydrobiopterin and Dopamine Release

open access: yesPteridines, 1995
We previously reported that intracerebroventricular administration of 6R-L-erythro-5,6,7,8-tetrahydrobiopterin (6R-BJL), a cofactor for aromatic amino acid hydroxylases and nitric oxide synthase, induces an increase in DOPA levels (as an index of DA ...
Miwa Soichi, Koshimura Kunio
doaj   +1 more source

GABA storage and release in the medial globus pallidus in L-DOPA-induced dyskinesia priming

open access: yesNeurobiology of Disease, 2020
Levo-dihydroxyphenylalanine (L-DOPA) is the most effective treatment for Parkinson's disease; however, most patients develop uncontrollable abnormal involuntary movements known as L-DOPA-induced dyskinesia.
Haruo Nishijima   +10 more
doaj   +1 more source

Secretion of Dopa in Phaeochromocytoma [PDF]

open access: yesBMJ, 1972
In a series of 11 cases with phaeochromocytoma, two patients were found in whom the tumour secreted dopa in addition to dopamine, noradrenaline, and adrenaline. These two patients were normotensive in spite of high plasma and urinary levels of noradrenaline and adrenaline.
W J, Louis   +3 more
openaire   +2 more sources

Metabolic engineering of Escherichia coli BL21 (DE3) for de novo production of l-DOPA from d-glucose

open access: yesMicrobial Cell Factories, 2019
BackgroundProduction of l-tyrosine is gaining grounds as the market size of 3,4-dihydroxyphenyl-l-alanine (l-DOPA) is expected to increase due to increasing cases of Parkinson’s disease a neurodegenerative disease.
E. Fordjour   +4 more
semanticscholar   +1 more source

The Digital Observatory for Protected Areas (DOPA) Explorer 1.0 [PDF]

open access: yes, 2015
The Digital Observatory for Protected Areas (DOPA) has been developed to support the European Union’s efforts in strengthening our capacity to mobilize and use biodiversity data, information and forecasts so that they are readily accessible to ...
Martinez-Lopez, Javier   +6 more
core   +1 more source

Table1_Doxycycline attenuates l-DOPA-induced dyskinesia through an anti-inflammatory effect in a hemiparkinsonian mouse model.doc

open access: yes, 2022
The pharmacological manipulation of neuroinflammation appears to be a promising strategy to alleviate l-DOPA-induced dyskinesia (LID) in Parkinson’s disease (PD).
Patrick Pierre Michel (2019922)   +5 more
core   +1 more source

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