Results 21 to 30 of about 112,750 (306)
OBJETIVO: Avaliar os efeitos na função ventricular esquerda do uso precoce e tardio de dopamina, em modelo experimental de coração isolado. MÉTODO: Foram utilizados 60 coelhos em modelo de coração isolado mantido por animal suporte.
Ademar R. Souza +4 more
doaj +1 more source
Levodopa (L-DOPA) is the most effective drug for Parkinson's disease (PD). However, the response to L-DOPA remains individually variable, which hampers the practical value of L-DOPA in the clinic. Genetic factors play a role in L-DOPA efficacy.
Lanting Li +6 more
doaj +1 more source
Norepinephrine and dopamine increase motility, biofilm formation and virulence of Vibrio harveyi [PDF]
Vibrio harveyi is one of the major pathogens of aquatic organisms, affecting both vertebrates and invertebrates, and causes important losses in the aquaculture industry.
Bossier, Peter +3 more
core +2 more sources
Faba bean (Vicia faba L.) has been identified as a rich source of l-DOPA, which is used in treating Parkinson's disease. Biosynthesis and accumulation of active substances such as l-DOPA in plant tissues may interact with growing conditions and ...
Fatemeh Etemadi +4 more
doaj +1 more source
PET Studies of Cerebral Levodopa Metabolism: A Review of Clinical Findings and Modeling Approaches [PDF]
[18F]Fluoro-3,4-dihydroxyphenyl-l-alanine (FDOPA) was one of the first successful tracers for molecular imaging by positron emission tomography (PET), and has proven immensely valuable for studies of Parkinson’s disease.
Cumming, Paul, Kumakura, Yoshitaka
core +1 more source
We examined the inhibitory effect of tetrahydrobiopterin (BPH4) on L-β-(3,4-dihydroxyphenyl)alanine (DOPA)-induced cytotoxicity in PC-12 cells. First in vitro inhibitory efficacy of BPH4 on lipid peroxidation induced by Fe3+-DOPA complex was confirmed by
Kojima Shuji +4 more
doaj +1 more source
Striatal astrocytes act as a reservoir for L-DOPA.
L-DOPA is therapeutically efficacious in patients with Parkinson's disease (PD), although dopamine (DA) neurons are severely degenerated. Since cortical astrocytes express neutral amino acid transporter (LAT) and DA transporter (DAT), the uptake and ...
Masato Asanuma +4 more
doaj +1 more source
Plasma catecholamines during activation of the sympathetic nervous system in a patient with Shy-Drager syndrome. [PDF]
Plasma catecholamines and circulation parameters were studied in a patient with a Shy-Drager syndrome. Basal values of free noradrenaline and dopamine were within the normal range, whereas the adrenaline level was decreased.
Gross, G. +2 more
core +1 more source
An Overview of Methods for L-Dopa Extraction and Analytical Determination in Plant Matrices
L-dopa is a precursor of dopamine used as the most effective symptomatic drug treatment for Parkinson’s disease. Most of the L-dopa isolated is either synthesized chemically or from natural sources, but only some plants belonging to the Fabaceae family ...
Carmen Tesoro +5 more
doaj +1 more source
Effects of cocaethylene on dopamine and serotonin synthesis in Long–Evans and Sprague–Dawley brains [PDF]
We examined the behavioral and neurochemical effects of cocaethylene treatment in Long–Evans ( LE). and Sprague–Dawley (SD) rats. Cocaethylene-induced behaviors were significantly less in LE rats.
Baumann, Dr. M.H. +3 more
core +1 more source

