Results 161 to 170 of about 24,273 (376)
Local Field Potential‐Based Programming: A Proof‐of‐Concept Pilot Study
Abstract Objectives Programming deep brain stimulation (DBS) is still based on a trial‐and‐error approach, often becoming a time‐consuming process for both treating physicians and patients. Several strategies have been proposed to streamline DBS programming, most of which are preliminary and mainly address Parkinson's disease, a condition readily ...
Alfonso Fasano+10 more
wiley +1 more source
18F-Dihydroxyphenylalanine PET in Patients with Biochemical Evidence of Medullary Thyroid Cancer: Relation to Tumor Differentiation [PDF]
Klaas Pieter Koopmans+7 more
openalex +1 more source
Characterisation and properties of a small cell lung cancer cell line and xenograft WX322 with marked sensitivity to alpha-interferon. [PDF]
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core +1 more source
Abstract Background Glial cell line–derived neurotrophic factor (GDNF) is required for development and survival of dopaminergic neurons. A previous trial evaluating lower‐dose adeno‐associated virus serotype 2–GDNF (AAV2‐GDNF) bilateral intraputaminal infusion in participants with advanced Parkinson's disease (PD) achieved 26% mean putaminal coverage ...
Amber D. Van Laar+10 more
wiley +1 more source
Cholinergic System Changes in Dopa‐Unresponsive Freezing of Gait in Parkinson's Disease
Abstract Background Freezing of gait (FoG) is a debilitating mobility disturbance that becomes increasingly resistant to dopaminergic pharmacotherapies with advancing Parkinson's disease (PD). The pathophysiology underlying the response of FoG to dopaminergic treatment is poorly understood.
Kelvin L. Chou+6 more
wiley +1 more source
L-Dihydroxyphenylalanine modulates the steady-state expression of mouse striatal tyrosine hydroxylase, aromatic L-amino acid decarboxylase, dopamine and its metabolites in an MPTP mouse model of Parkinson's disease [PDF]
Jennifer King+4 more
openalex +1 more source
Levodopa‐Responsive Dystonia Secondary to CTNNB1 Neurodevelopmental Disorder
Movement Disorders Clinical Practice, EarlyView.
Hanin Algethami+5 more
wiley +1 more source
Abstract Background Fatigue in Parkinson's disease (PD) is a prevalent and debilitating non‐motor symptom. Despite its significant impact on quality of life, the underlying neurochemical and network‐based mechanisms remain poorly understood. Objectives This observational study applied a multimodal imaging approach to explore potential links between the
Ilaria Antonella Di Vico+14 more
wiley +1 more source