Results 221 to 230 of about 24,273 (376)

The Tyrosinase-Tyrosine Reaction: Production of l-3.4-Dihydroxyphenylalanine from Tyrosine.

Biochemical Journal
H. Raper
semanticscholar   +1 more source

The CRISPR‐Cas9 knockout DDC SH‐SY5Y in vitro model for AADC deficiency provides insight into the pathogenicity of R347Q and L353P variants: a cross‐sectional structural and functional analysis

The FEBS Journal, EarlyView.
Here, we generated a DDC‐KO cellular model for studying aromatic amino acid decarboxylase (AADC) deficiency. This model was created using CRISPR‐Cas9 in the SH‐SY5Y neuroblastoma cell line and was validated through the absence of the dopamine product and an altered l‐dopa metabolite profile.
Cristian Andres Carmona‐Carmona, Giovanni Bisello, Rossella Franchini, Gianluigi Lunardi, Roberta Galavotti, Massimiliano Perduca, Rui P. Ribeiro, Benny Danilo Belviso, Alejandro Giorgetti, Rocco Caliandro, Patricia M.‐J. Lievens, Mariarita Bertoldi   +11 more
wiley   +1 more source

Cholinergic dysfunction in isolated rapid eye movement sleep behaviour disorder links to impending phenoconversion. [PDF]

Eur J Neurol
Terkelsen MH, Iranzo A, Serradell M, Baun AM, Stokholm MG, Danielsen EH, Østergaard K, Otto M, Svendsen KB, Møller M, Johnsen EL, Garrido A, Vilas D, Santamaria J, Møller A, Gaig C, Brooks DJ, Borghammer P, Tolosa E, Pavese N.   +19 more
europepmc   +1 more source

Comparative metabolism of d-and l-3,4-dihydroxyphenylalanine in normal and pyridoxine-deficient rats [PDF]

, 1964
TL Sourkes, H Wiseman-Distler, Moran Jf, G.F. Murphy, Simone Saint Cyr   +4 more
openalex   +1 more source

Studies on the binding of DOPA (3,4‐dihydroxyphenylalanine) to tRNA

FEBS Letters, 1978
G. Kreil, H. Bernheimer, G. Högenauer
openaire   +3 more sources

In vivo and in silico models of Drosophila for Parkinson's disease

The FEBS Journal, EarlyView.
In vivo and in silico models of Drosophila offer valuable advantages in the generation, analysis, and interpretation of complex biological data, thereby significantly advancing our understanding of Parkinson's disease. Molecular‐level measurements and phenotypic data from Drosophila are extensively utilised in metabolic network modeling and artificial ...
Müberra Fatma Cesur, Rachel Strazdins, Souvarish Sarkar, Tunahan Çakır   +3 more
wiley   +1 more source

Extensive Dysregulation of Phenylalanine Metabolism Is Associated With Stress Hyperphenylalaninemia and 30-Day Death in Critically Ill Patients With Acute Decompensated Heart Failure. [PDF]

J Am Heart Assoc
Chen WS, Liu MH, Tsou YL, Wu HP, Lin HC, Liang CY, Wang CH.   +6 more
europepmc   +1 more source

Multiple electrophoresis peaks of rat liver decarboxylases for 3,4-dihydroxyphenylalanine and 5-hydroxytryptophan [PDF]

, 1969
Walter F. Coulson, David A Bender, J.B. Jepson   +2 more
openalex   +1 more source

Arterio-venous differences in cord levels of catecholamines, glucose, lactate and blood gases [PDF]

, 2016
Eisenhofer, Graeme, Hume, Robert, Koh, Daisy K M, Watson, Jennifer, Williams, Fiona L R   +4 more
core   +2 more sources

Self‐reported autonomic dysfunction could be a predictive marker for sarcopenia in Parkinson's disease

Geriatrics &Gerontology International, EarlyView.
Autonomic dysfunction, assessed by the Scales for Outcomes in Parkinson's Disease‐Autonomic Questionnaire, was significantly associated with sarcopenia in patients with Parkinson's disease. Among all autonomic domains, the gastrointestinal score had the strongest predictive ability for sarcopenia.
Motohiro Okumura, Yohei Mukai, Reiko Saika, Yuji Takahashi   +3 more
wiley   +1 more source