Results 31 to 40 of about 24,273 (376)

Genetic incorporation of l-dihydroxyphenylalanine (DOPA) biosynthesized by a tyrosine phenol-lyase.

open access: yesChemical Communications, 2018
l-Dihydroxyphenylalanine (DOPA) was biosynthesized by a tyrosine-phenol lyase from catechol, pyruvate, and ammonia in Escherichia coli, and the biosynthesized amino acid was directly incorporated into proteins.
Sanggil Kim, B. Sung, S. C. Kim, H. Lee
semanticscholar   +1 more source

Dopamine D 4 Receptor-Deficient Mice Display Cortical Hyperexcitability [PDF]

open access: yes, 2001
The dopamine D(4) receptor (D(4)R) is predominantly expressed in the frontal cortex (FC), a brain region that receives dense input from midbrain dopamine (DA) neurons and is associated with cognitive and emotional processes.
Ariano, Marjorie A.   +11 more
core   +1 more source

The Use of the Calcitonin Minimal Recognition Module for the Design of DOPA-Containing Fibrillar Assemblies

open access: yesNanomaterials, 2014
Amyloid deposits are insoluble fibrous protein aggregates, identified in numerous diseases, which self-assemble through molecular recognition. This process is facilitated by short amino acid sequences, identified as minimal modules.
Galit Fichman   +3 more
doaj   +1 more source

Silk/Natural Rubber (NR) and 3,4-Dihydroxyphenylalanine (DOPA)-Modified Silk/NR Composites: Synthesis, Secondary Structure, and Mechanical Properties

open access: yesMolecules, 2020
Silk composites with natural rubber (NR) were prepared by mixing degummed silk and NR latex solutions. A significant enhancement of the mechanical properties was confirmed for silk/NR composites compared to a NR-only product, indicating that silk can be ...
Hiromitsu Sogawa   +3 more
doaj   +1 more source

Principles of personalized medicine and modern pharmaceutical technologies to optimize levodopa therapy of Parkinson's disease

open access: yesАнналы клинической и экспериментальной неврологии, 2021
Levodopa (3-hydroxy-L-tyrosine, the levorotatory isomerof 3,4-dihydroxyphenylalanine) is a biological precursor of the neurotransmitter dopamine and has been the "gold standard" in the treatment of Parkinsons disease for over 50 years. The widespread use
Denis А. Abaimov   +6 more
doaj   +1 more source

3,4-Dihydroxyphenylalanine Peptides as Nonperturbative Quantum Dot Sensors of Aminopeptidase.

open access: yesACS Nano, 2016
Fluorescence-based assays for hydrolases that cleave within the substrate (endopeptidases) are common, while developing substrates for proteases that selectively cleave from peptide termini (exopeptidases) is more challenging, since the termini are ...
V. Palomo   +5 more
semanticscholar   +1 more source

Proximate composition and anti-nutritional factors in Mucuna pruriens (velvet bean) seed flour as affected by several processing methods

open access: yesHeliyon, 2023
Mucuna pruriens seed being an underutilized legume with antinutrients was processed to reduce antinutrients and improve nutritional quality. The seeds were cleaned, washed and subjected to single treatments of soaking (24 h, 48 h, 72 h), cooking (20 min,
Clement Chinedum Ezegbe   +4 more
doaj  

Magnetic resonance imaging-guided phase 1 trial of putaminal AADC gene therapy for Parkinson's disease. [PDF]

open access: yes, 2019
ObjectiveTo understand the safety, putaminal coverage, and enzyme expression of adeno-associated viral vector serotype-2 encoding the complementary DNA for the enzyme, aromatic L-amino acid decarboxylase (VY-AADC01), delivered using novel intraoperative ...
Bankiewicz, Krystof S   +10 more
core   +1 more source

Rheology and Gelation of Hyaluronic Acid/Chitosan Coacervates

open access: yesBiomolecules, 2022
Hyaluronic acid (HA) and chitosan (CHI) are biopolyelectrolytes which are interesting for both the medical and polymer physics communities due to their biocompatibility and semi-flexibility, respectively.
A. Basak Kayitmazer   +3 more
doaj   +1 more source

????????? ?????????????????? ????????? ????????? ?????? ??????????????? ??????????????? ?????? ???????????? ?????? [PDF]

open access: yes, 2020
Department of Chemical EngineeringLignin peroxidase is promising ingredient for skin whitening cosmetics because it is capable of oxidizing melanin with high redox potential.
Sung, Ho Joon
core  

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