Results 41 to 50 of about 20,405 (323)

Proanthocyanidins Extracted from Rhododendron pulchrum Leaves as Source of Tyrosinase Inhibitors: Structure, Activity, and Mechanism. [PDF]

open access: yesPLoS ONE, 2015
The objective of this study was to assess the structure, anti-tyrosinase activity, and mechanism of proanthocyanidins extracted from Rhododendron pulchrum leaves.
Wei-Ming Chai   +6 more
doaj   +1 more source

Mid-gut ACTH-secreting neuroendocrine tumor unmasked with (18)F-dihydroxyphenylalanine-positron emission tomography. [PDF]

open access: yes, 2015
Ectopic ACTH Cushing's syndrome (EAS) is often caused by neuroendocrine tumors (NETs) of lungs, pancreas, thymus, and other less frequent locations. Localizing the source of ACTH can be challenging.
Boubaker, A.   +8 more
core   +1 more source

L-3,4-dihydroxyphenylalanine Accumulation in Faba Bean (Vicia faba L.) Tissues during Different Growth Stages

open access: yesAgronomy, 2021
L-3,4-dihydroxyphenylalanine (L-dopa)-rich faba (Vicia faba L.) tissues are a potentially useful source for its pharmaceutical purpose, although the species contains health curious vicine and convicine in the seeds.
Shucheng Duan   +5 more
doaj   +1 more source

Maladaptive plasticity in levodopa-induced dyskinesias and tardive dyskinesias: old and new insights on the effects of dopamine receptor pharmacology. [PDF]

open access: yes, 2014
Maladaptive plasticity can be defined as behavioral loss or even development of disease symptoms resulting from aberrant plasticity changes in the human brain.
Ahmed   +58 more
core   +2 more sources

l-DOPA and Its Receptor GPR143: Implications for Pathogenesis and Therapy in Parkinson’s Disease

open access: yesFrontiers in Pharmacology, 2019
l-3,4-Dihydroxyphenylalanine (l-DOPA) is the most effective therapeutic agent for Parkinson’s disease (PD). l-DOPA is traditionally believed to be an inert amino acid that exerts actions and effectiveness in PD through its conversion to dopamine.
Yoshio Goshima   +4 more
doaj   +1 more source

Mussel adhesive protein inspired coatings: a versatile method to fabricate silica films on various surfaces [PDF]

open access: yes, 2012
A simple and versatile biomimetic strategy for the fabrication of silica films on a variety of substrates including gold, polystyrene and silicon wafers was developed using nanogram amounts per cm 2 of silicatein.
Akhilesh Rai   +68 more
core   +1 more source

Mussel-Inspired Catechol-Functionalized Hydrogels and Their Medical Applications

open access: yesMolecules, 2019
Mussel adhesive proteins (MAPs) have a unique ability to firmly adhere to different surfaces in aqueous environments via the special amino acid, 3,4-dihydroxyphenylalanine (DOPA).
Wei-Yan Quan   +7 more
doaj   +1 more source

Antiparkinsonian efficacy of guanosine in rodent models of movement disorder [PDF]

open access: yes, 2017
Guanosine (GUO) is a guanine-based purine nucleoside with important trophic functions and promising neuroprotective properties. Although the neuroprotective effects of GUO have been corroborated in cellular models of Parkinson's disease (PD), its ...
Ciruela Alférez, Francisco   +5 more
core   +1 more source

Smart, Bio‐Inspired Polymers and Bio‐Based Molecules Modified by Zwitterionic Motifs to Design Next‐Generation Materials for Medical Applications

open access: yesAdvanced Functional Materials, EarlyView.
Bio‐based and (semi‐)synthetic zwitterion‐modified novel materials and fully synthetic next‐generation alternatives show the importance of material design for different biomedical applications. The zwitterionic character affects the physiochemical behavior of the material and deepens the understanding of chemical interaction mechanisms within the ...
Theresa M. Lutz   +3 more
wiley   +1 more source

Versatile Mitogenic and Differentiation‐Inducible Layer Formation by Underwater Adhesive Polypeptides

open access: yesAdvanced Science, 2021
Artificial materials have no biological functions, but they are important for medical devices such as artificial organs and matrices for regenerative medicine.
Seiichi Tada   +12 more
doaj   +1 more source

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