Results 141 to 150 of about 9,923 (262)

Peripheral κ opioid receptor in pain and inflammation: From molecular signalling and gene expression to drug discovery

open access: yesBritish Journal of Pharmacology, EarlyView.
The κ opioid receptor (κ receptor, KOR) is a G protein‐coupled receptor with well established roles in analgesia and immune modulation. Although historically studied primarily in the central nervous system (CNS), growing evidence indicates that κ signalling in peripheral tissues plays an important role in regulating pain, inflammation and immune ...
Rumsha Khan   +3 more
wiley   +1 more source

Characterization of dermatan sulfate and chondroitin sulfate profiles during brain regeneration in Styela plicata

open access: yesThe FEBS Journal, EarlyView.
Adult ascidians are capable of regenerating their entire brains following injury, and glycosaminoglycans have been shown to either promote or inhibit neuritogenesis. In this study, dermatan 2,6‐disulfate (D2,6S) was identified as the predominant complex carbohydrate in the ascidian brain.
Taynan Motta Portal   +5 more
wiley   +1 more source

Real‐world evidence for the efficacy and tolerability of an isobutylamido‐thiazolyl‐resorcinol (Thiamidol)‐containing skincare regimen on facial hyperpigmentation and overall skin appearance: A multi‐centre study in 11 European countries

open access: yesInternational Journal of Cosmetic Science, EarlyView.
A Thiamidol‐containing skincare regimen showed significant improvement in facial hyperpigmentation in a real‐world study across 11 European countries. The treatment led to a significant reduction in mMASI scores, enhanced overall skin condition and demonstrated high tolerability.
B. Schuster   +12 more
wiley   +1 more source

Time‐calibrated relationships of a rare cave catfish (Trichomycterus rubbioli): Shedding light on troglobitic lifestyle origin in the Brazilian caatinga

open access: yesJournal of Fish Biology, EarlyView.
Abstract Catfishes of the subfamily Trichomycterinae comprise the most diverse fish group with species adapted to live in Neotropical caves, but past evolutionary scenarios that have driven the origin of these troglobitic species remain unknown. We herein investigate the phylogenetic position of the cave‐restricted Trichomycterus rubbioli, endemic to ...
Wilson J. E. M. Costa   +6 more
wiley   +1 more source

Dihydroxyphenylalanine and Hydroxytyramine in Mammalian Suprarenals. [PDF]

open access: yesActa Chemica Scandinavica, 1950
McC. Goodall   +3 more
openaire   +1 more source

Dietary L‐Tyrosine Sustains Egg Production and Quality by Modulating Promoter CpG Methylation, Gene Expression, and Hormone Profiles in Reproductive Signalling Pathways of Aged Laying Hens

open access: yesJournal of Animal Physiology and Animal Nutrition, EarlyView.
ABSTRACT Managing prolactin (PRL)‐mediated reproductive suppression is critical for maintaining egg production in commercial laying hens. L‐tyrosine (TYR), a precursor of dopamine (DA), may counteract age‐related reproductive decline by suppressing PRL, thereby sustaining productivity and egg quality in late‐phase laying hens.
Hasan Hüseyin İpçak
wiley   +1 more source

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