Results 91 to 100 of about 34,830 (218)
Brazilian Journal of Cardiovascular Surgery, 2015 Objective: This study aimed to show the effects of intra-operative diltiazem infusion on flow in arterial and venous grafts in coronary artery bypass graft surgery. Methods: Hundred fourty patients with a total of 361 grafts [205 (57%) arterial and 156 (
Ozan Erdem +6 more
doaj +1 more source
A Case Report of Angioedema and Anaphylactic Shock Induced by Ingestion of Polyethylene Glycol [PDF]
, 2020 Introduction: We report one of few documented cases of a severe anaphylactic reaction with angioedema to polyethylene glycol (PEG).Case Report: The patient presented 30 minutes after onset of his symptoms and quickly developed hypoxia and hypotension ...
Osborn, Lesley, Rossi, Amy
core
Contact Dermatitis, Volume 94, Issue 3, Page 272-285, March 2026.Allergic contact dermatitis is very common in patients with anogenital lesions referred for patch testing in Spain. Key allergens include fragrances, preservatives and topical treatments like anaesthetics and steroids. Emerging sensitisers including benzisothiazolinone and sodium metabisulphite are also relevant.
Mercè Grau‐Pérez +29 more
wiley +1 more source
Expert consensus document: A 'diamond' approach to personalized treatment of angina. [PDF]
, 2017 In clinical guidelines, drugs for symptomatic angina are classified as being first choice (β-blockers, calcium-channel blockers, short-acting nitrates) or second choice (ivabradine, nicorandil, ranolazine, trimetazidine), with the recommendation to ...
A Abbate +101 more
core +1 more source
Clinical and Translational Science, Volume 19, Issue 3, March 2026.ABSTRACT Nirmatrelvir boosted with ritonavir is a key antiviral against COVID‐19, yet ritonavir's potent CYP3A4 inhibition exposes patients to numerous drug–drug interactions. To make prescribing safer, a national proactive system providing expert pharmacology advice was implemented in France.
Youssef Libiad +7 more
wiley +1 more source
Antimicrobial activities of Diltiazem Hydrochloride: drug repurposing approach [PDF]
PeerJBackground The growing concern of antibiotic-resistant microbial strains worldwide has prompted the need for alternative methods to combat microbial resistance.
Omar K. Alduaij +3 more
doaj +2 more sources
A Case of Atrial Fibrillation from Cyclosporine Toxicity [PDF]
, 2004 We describe the unusual occurrence of atrial fibrillation immediately after a seizure in a young patient with cyclosporine toxicity. The new onset atrial fibrillation was triggered by high levels of cyclosporine and possibly facilitated by the ...
Sanghi, Pramod, Ahmad, Masood
core
Properties of Cyclic-Nucleotide Gated Channels Mediating Olfactory Transduction - Activation, Selectivity, and Blockage [PDF]
, 1992 Cyclic nucleotide-gated channels (cng channels) in the sensory membrane of olfactory receptor cells, activated after the odorant-induced increase of cytosolic cAMP concentration, conduct the receptor current that elicits electrical excitation of the ...
Frings, S, Lindemann, B, Lynch, JW
core +2 more sources
A Facile Protocol for C(sp2)–C(sp3) Bond Formation Reactions Toward Functionalized E3 Ligase Ligands
ChemMedChem, Volume 21, Issue 4, 25 February 2026.A robust C(sp2)–C(sp3) decarboxylative coupling strategy enables access to new CRBN ligands and degraders with improved physicochemical properties. This synthetic approach is expanding the chemical space beyond C(sp2)–N linkages, fine‐tuning proteolysis‐targeting chimera activities and unlocking previously inaccessible degrader chemotypes.
Anita Maksutova +15 more
wiley +1 more source
Frontiers in PharmacologyBackgroundTacrolimus is widely used to treat pediatric nephrotic range proteinuria (NRP). Diltiazem, a CYP3A4/5 inhibitor, is often administered with tacrolimus, affecting its pharmacokinetic profile. The impact of this combination on tacrolimus exposure,
Qiaoling Yang +10 more
doaj +1 more source