Results 71 to 80 of about 34,830 (218)

Catheter ablation vs. antiarrhythmic drug therapy in patients with symptomatic atrioventricular nodal re-entrant tachycardia: a randomized, controlled trial. [PDF]

, 2017
Aims: To conduct a randomized trial in order to guide the optimum therapy of symptomatic atrioventricular nodal re-entrant tachycardia (AVNRT).
Camm, AJ, Giazitzoglou, E, Josephson, ME, Katritsis, DG, Katritsis, GD, Paxinos, G, Vachliotis, V, Zografos, T   +7 more
core   +1 more source

Electromechanical modelling and simulation of human‐induced pluripotent stem cell‐derived cardiomyocytes predict drug‐induced contractility effects

The Journal of Physiology, EarlyView.
Abstract figure legend A study described in this paper describes a new tool for hiPSC‐CM electromechanical behaviour simulations using mathematical modelling. The model enables in silico assays making drug testing quick, comprehensive and accurate. New hiPSC‐CM models can be used as a platform to integrate in vitro and in silico findings.
Milda Folkmanaite, Xin Zhou, Andreas Koschinski, Wan‐Hua Hong, Marilù Casini, Manuel Koch, Ursula Ravens, Remi Peyronnet, Manuela Zaccolo, Blanca Rodriguez   +9 more
wiley   +1 more source

Evaluation of gut modulatory and bronchodilator activities of Amaranthus spinosus Linn. [PDF]

, 2012
Background The aqueous-methanolic extract of Amaranthus spinosus (A. spinosus Linn.,) whole plant, was studied for its laxative, spasmolytic and bronchodilator activities to validate some of its medicinal uses. Methods The crude extract of A.
A Hilou, A Khan, ABS Kumar, AF Brading, AH Gilani, AH Gilani, AH Gilani, AH Gilani, AH Gilani, AH Gilani, AH Gilani, AH Gilani, AJ Farre, AK Haruna, Anwarul-Hassan Gilani, B Sangameswaran, BB Hoffman, BJ Undem, C Wiart, CP Khare, EM Williamson, FC Stintzing, G Blunden, HS Mathewson, Imran Imran, JC Ibewuike, JH Brown, JM Van-Rossum, K Srinivasan, KR Kirtikar, M Azhar-ul-Haq, Malik Hassan Mehmood, MH Mehmood, MKS Kumar, Mueen Ahmad Chaudhary, Najeeb-ur Rehman, National Research Council, NU Rehman, O Longman, Q Jabeen, RA Teutonico, RP Rastogi, S Bashir, SAH Gilani, Samra Bashir, SR Baquar, T Ahmed, TC Westfall, Z Hussain, Z Hussain, Z Hussain   +50 more
core   +4 more sources

Antiplasmodial Activity and Pharmacokinetic Profiling of Cryptolepine and 2,7‐Dibromocryptolepine With a View to Informing the Design of Novel Antimalarial Cryptolepine Analogues

Drug Development Research, Volume 87, Issue 2, April 2026.
ABSTRACT The roots of the climbing shrub Cryptolepis sanguinolenta are traditionally used in West Africa for the treatment of malaria. The principal constituent, cryptolepine (1), has been shown to have antimalarial activity but there are concerns regarding its toxicity on account of its DNA‐intercalating property.
Elodie Chenu, James Duffy, Arnold Donkor Forkuo, Stephen Y. Gbedema, Seham Abdelall, Muhammad Wahajuddin, Huw S. Jones, Colin W. Wright   +7 more
wiley   +1 more source

Diltiazem [PDF]

Canadian Anaesthetists’ Society Journal, 1985
  +5 more sources

Effects of simulated weightlessness on regional blood flow specifically during cardiovascular stress [PDF]

Significant changes in the cardiovasular system of humans and animals have been observed following exposure to prolonged periods of weightlessness during space flight.
Harrison, D. C.
core   +1 more source

Rate-dependent and antiarrhythmic reentrant tachycardia (AVNRT) effects of simvastatin in isolated rabbit atrioventricular nodal model [PDF]

, 2010
Background and purpose: Several previous studies have shown the direct and indirect effects of statins on supraventricular and ventricular arrhythmia. The purpose of the present study is to determine (1) whether Simvastatin modifies the rate-dependent ...
Alizadeh, A.M., Alizadeh, F., Badaghabadi, F., Changizi, S., Khori, V., Najafi, S.A., Nayebpour, M., Pourabouk, M., Salehi, A.   +8 more
core  

The Evolving Role of Ivabradine for Focal Atrial Tachycardia: A Systematic Review

Journal of Arrhythmia, Volume 42, Issue 2, April 2026.
Overview of the evolving role of ivabradine in focal atrial tachycardia (FAT), highlighting its HCN‐mediated mechanism, features of ivabradine‐sensitive FAT, hypothesized predictors of response, special populations requiring special considerations, and potential adverse effects.
Haikal Balweel, Rifqi Rizkani Eri, Sania Zahrani, Kiara Hanna Quinncilla, Novaro Adeneur Tafriend, Agus Harsoyo   +5 more
wiley   +1 more source

Pharmacokinetics of diltiazem hydrochloride delay-onset sustained-release pellet capsules in healthy volunteers

Brazilian Journal of Pharmaceutical Sciences, 2013
The pharmacokinetics (PK) of ordinary tablets and sustained release capsules of diltiazem hydrochloride in human clinical trials had been studied. The PK of diltiazem hydrochloride delay-onset sustained-release pellet capsules, a new dosage form, has not
Xi-Qing Yan, Zhi-Gang Chen, Rong-Liang Wang, Jun Yang, Fang Ai, Yan-Juan Pan, Pei-Yong Qiu, Da-Xin Wang   +7 more
doaj  

Kawasaki Disease Accompanied by Acute Generalized Exanthematous Pustulosis

Clinical Case Reports, Volume 14, Issue 3, March 2026.
ABSTRACT Acute generalized exanthematous pustulosis (AGEP) is a rare but serious adverse skin reaction usually caused by drugs. We reported a 4‐year‐old boy diagnosed with Kawasaki disease (KD) accompanied by AGEP who presented with typical symptoms of KD, including fever, scarlet‐like rash, swollen extremities, cervical lymph node swelling ...
Wen Li, Qi Jia, Shu Teng, Huaping Wang, Zhenghong Qi   +4 more
wiley   +1 more source