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Synthesis of Illudinine from Dimedone

Organic Letters, 2017
A total synthesis of the illudalane sesquiterpene illudinine was realized in eight steps and 14% overall yield from commercially available dimedone. The approach features tandem fragmentation/Knoevenagel-type condensation and microwave-assisted oxidative cycloisomerization to establish the isoquinoline core.
Alec E. Morrison   +3 more
openaire   +2 more sources

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