Results 81 to 90 of about 679,917 (339)

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

open access: yesMolecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan   +16 more
wiley   +1 more source

6-Bromo-1,2,3,4-tetrahydroquinoline-8-carbonitrile

open access: yesIUCrData, 2016
In the title compound, C10H9BrN2, one of the methylene groups of the piperidine ring is disordered over two sets of sites in a 0.692 (8):0.308 (8) ratio, which leads to two envelope conformations.
Ísmail Çelik   +4 more
doaj   +1 more source

Integrability and conformal data of the dimer model

open access: yes, 2016
The central charge of the dimer model on the square lattice is still being debated in the literature. In this paper, we provide evidence supporting the consistency of a $c=-2$ description.
Morin-Duchesne, Alexi   +2 more
core   +1 more source

Chameleon sequences reveal structural effects in proteins representing micelle‐like distribution of hydrophobicity

open access: yesFEBS Open Bio, EarlyView.
Amino acids sequence of two different proteins with the same sequence (chameleon sequence—black boxes) represent in 3D structure of the proteins different secondary structures: HHHH—helical and BBB—Beta‐structural. The chains folded in water environment adopt different III‐order structures in which the chameleon fragments appear to adopt similar status
Irena Roterman   +4 more
wiley   +1 more source

Crystal structure of (E)-undec-2-enoic acid

open access: yesActa Crystallographica Section E: Crystallographic Communications, 2015
In the molecule of the title low-melting α,β-unsaturated carboxylic acid, C11H20O2, the least-squares mean line through the octyl chain forms an angle of 60.10 (13)° with the normal to plane of the acrylic acid fragment (r.m.s. deviation = 0.008 Å).
Marcel Sonneck   +3 more
doaj   +1 more source

Abnormal Fano Profile in Graphene-Wrapped Dielectric Particle Dimer

open access: yesPhotonics, 2020
We give a theoretical study on the near field enhancement and far field spectrum of an adjacent graphene-wrapped sphere dimer with different radii. The Fano profile is found in the near field enhancement spectrum of such a symmetry-broken dimer system ...
Yang Huang, Pujuan Ma, Ya Min Wu
doaj   +1 more source

Exon 7 splicing of ERα predicts poor prognosis and increases phenotypic heterogeneity in luminal a subtype breast cancer

open access: yesFEBS Open Bio, EarlyView.
ERα splice variant ERα∆7 lacks the C‐terminus, and its expression may change phenotypes of breast cancers. Our results showed that ERα∆7 is found in the luminal A subtype, and elevated ERα∆7 levels are linked to improved cell survival with lower proliferation and migration.
Long Wai Tsui   +10 more
wiley   +1 more source

Inversion of spin levels in exchange-coupled pairs under combined time reversal

open access: yesSemiconductor Physics, Quantum Electronics & Optoelectronics, 2018
The method for transforming antiferromagnetic exchange interaction into the ferromagnetic one has been proposed for binuclear coordination compounds, which contain dimers consisting of iron or rare earth ions with arbitrary spins and having identical ...
I.I. Geru
doaj   +1 more source

Observation of an Efimov resonance in an ultracold mixture of atoms and weakly bound dimers

open access: yes, 2009
We discuss our recent observation of an atom-dimer Efimov resonance in an ultracold mixture of Cs atoms and Cs_2 Feshbach molecules [Nature Phys. 5, 227 (2009)]. We review our experimental procedure and present additional data involving a non-universal g-
Braaten E   +18 more
core   +1 more source

YIPFα1A expression is regulated by multilayered molecular mechanisms

open access: yesFEBS Open Bio, EarlyView.
YIPFα1A, a five‐pass Golgi protein, is regulated at multiple layers. (1) Rare‐codon enrichment drives translation‐coupled mRNA decay. (2) A proximal 3′‐UTR element stabilizes mRNA. (3) A distal 3′‐UTR element included by alternate poly(A) site usage represses translation, which can be overridden by the proximal 3′‐UTR element.
Tokio Takaji   +2 more
wiley   +1 more source

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