Results 11 to 20 of about 2,747 (206)

Acrolein scavenger dimercaprol offers neuroprotection in an animal model of Parkinson’s disease: implication of acrolein and TRPA1

open access: yesTranslational Neurodegeneration, 2021
Background The mechanisms underlying lesions of dopaminergic (DA) neurons, an essential pathology of Parkinson’s disease (PD), are largely unknown, although oxidative stress is recognized as a key factor.
Liangqin Shi   +7 more
doaj   +2 more sources

Dimercaprol

open access: yesReactions Weekly
Dawn L, Whited L.
europepmc   +3 more sources

Unilateral rubral tremors in Wilson′s disease treated with dimercaprol

open access: yesAnnals of Indian Academy of Neurology, 2015
Tremors are reported as the most frequent neurological manifestation of Wilson′s disease (WD) in some series. Postural tremors, rest tremors, action tremors and wing-beating (rubral) tremors are the different types of tremors seen in WD.
Rahul T Chakor   +3 more
doaj   +2 more sources

Chelation Therapy for Rare Earth Element Toxicity: Current Evidence, Challenges and Future Directions. [PDF]

open access: yesBasic Clin Pharmacol Toxicol
ABSTRACT The accelerating integration of rare earth elements (REEs) in advanced technologies has generated rising concern over human exposure and the attendant toxicological risks. This review presents an up‐to‐date synthesis of current evidence on REE toxicity across multiple exposure pathways, including inhalation, ingestion and occupational contact,
Domingo JL.
europepmc   +2 more sources

Dimercaprol [PDF]

open access: yesDefinitions, 2020
A metal chelating agent that is used as an antidote in arsenic, gold, lead, mercury and other heavy metal poisoning. Metals form ligands in the body with the sulfhydryl groups of the pyruvate-oxidase enzyme system.
openaire   +2 more sources

A rare case report of lead encephalopathy due to high blood lead level. [PDF]

open access: yesClin Case Rep, 2023
Abstract Here we report a case of lead poisoning having a serum lead level of 412 mcg dL−1 who presented with decreasing level of consciousness and recurrent seizures. He responded well to treatment with chelation therapy.
Masbough F   +5 more
europepmc   +2 more sources

Cerebral Edema Secondary to Heavy Metal Toxicity From Siddha Medicine: A Case Report and Case‐Based Review [PDF]

open access: yesCase Reports in Neurological Medicine
Background Traditional Indian medicine has been used to treat a variety of illnesses for centuries. However, there are existing concerns surrounding its heavy metal content. Amongst the different systems of traditional Indian medicine, Ayurvedic medicine has been most frequently implicated in heavy metal toxicity, while Siddha medicine has only very ...
Tan Z   +7 more
europepmc   +2 more sources

Review on carbon dots: Synthesis and application in biology field

open access: yesBMEMat, Volume 1, Issue 4, December 2023., 2023
Carbon dots (CDs) based have remarkable effects in bioimaging, biosensing, drug delivery and disease treatment. This review summarizes the recent advances in CDs based on preparation and with different structures and biological functions. Perspectives on challenges and future trends are also discussed.
Xueting Li   +11 more
wiley   +1 more source

Cutaneous manifestations and treatment of arsenic toxicity: A systematic review

open access: yesSkin Health and Disease, Volume 3, Issue 4, August 2023., 2023
This article reviews the clinical spectrum of malignant and non‐malignant presentations of chronic arsenic toxicity. Abstract Cutaneous and systemic signs of acute and chronic arsenic poisoning may be vague. Thus, an awareness of these signs is crucial to prevent late or missed diagnoses.
Gia Toan Tang   +2 more
wiley   +1 more source

Severe chemical corneal injury from hexavalent chromium exposure: a case report

open access: yesToxicology Communications, 2022
Eye exposure to hexavalent chromium (Cr(VI)) acid can cause blindness. A 42-year-old man working in a plating operation presented to the emergency department following a workplace incident.
Daisuke Ueno   +6 more
doaj   +1 more source

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