Results 11 to 20 of about 2,161 (189)
Cerebral Edema Secondary to Heavy Metal Toxicity From Siddha Medicine: A Case Report and Case-Based Review. [PDF]
Case Rep Neurol MedBackground Traditional Indian medicine has been used to treat a variety of illnesses for centuries. However, there are existing concerns surrounding its heavy metal content. Amongst the different systems of traditional Indian medicine, Ayurvedic medicine has been most frequently implicated in heavy metal toxicity, while Siddha medicine has only very ...
Tan Z +7 more
europepmc +2 more sources
Chelation Therapy for Rare Earth Element Toxicity: Current Evidence, Challenges and Future Directions. [PDF]
Basic Clin Pharmacol ToxicolABSTRACT The accelerating integration of rare earth elements (REEs) in advanced technologies has generated rising concern over human exposure and the attendant toxicological risks. This review presents an up‐to‐date synthesis of current evidence on REE toxicity across multiple exposure pathways, including inhalation, ingestion and occupational contact,
Domingo JL.
europepmc +2 more sources
Development of a Library of Disulfide Bond-Containing Cationic Lipids for mRNA Delivery
Pharmaceutics, 2023 Lipid nanoparticles (LNPs) are the commonly used delivery tools for messenger RNA (mRNA) therapy and play an indispensable role in the success of COVID-19 mRNA vaccines. Ionizable cationic lipids are the most important component in LNPs.
Zhigao Shen +8 more
doaj +1 more source
Technology in Cancer Research & Treatment, 2021 Objective: To investigate the efficacy of a formula comprising arsenic trioxide and dimercaprol (BAL-ATO) as a radiosensitizing agent in model mice with pancreatic cancer xenografts. Methods: Female BALB/c nude mice bearing SW1990 human pancreatic cancer
Renyan Tang MD +4 more
doaj +1 more source
Translational Neurodegeneration, 2021 Background The mechanisms underlying lesions of dopaminergic (DA) neurons, an essential pathology of Parkinson’s disease (PD), are largely unknown, although oxidative stress is recognized as a key factor.
Liangqin Shi +7 more
doaj +1 more source
Review on carbon dots: Synthesis and application in biology field
BMEMat, Volume 1, Issue 4, December 2023., 2023 Carbon dots (CDs) based have remarkable effects in bioimaging, biosensing, drug delivery and disease treatment. This review summarizes the recent advances in CDs based on preparation and with different structures and biological functions. Perspectives on challenges and future trends are also discussed.
Xueting Li +11 more
wiley +1 more source
Cutaneous manifestations and treatment of arsenic toxicity: A systematic review
Skin Health and Disease, Volume 3, Issue 4, August 2023., 2023 This article reviews the clinical spectrum of malignant and non‐malignant presentations of chronic arsenic toxicity. Abstract Cutaneous and systemic signs of acute and chronic arsenic poisoning may be vague. Thus, an awareness of these signs is crucial to prevent late or missed diagnoses.
Gia Toan Tang +2 more
wiley +1 more source
Severe chemical corneal injury from hexavalent chromium exposure: a case report
Toxicology Communications, 2022 Eye exposure to hexavalent chromium (Cr(VI)) acid can cause blindness. A 42-year-old man working in a plating operation presented to the emergency department following a workplace incident.
Daisuke Ueno +6 more
doaj +1 more source
A rare case report of lead encephalopathy due to high blood lead level
Clinical Case Reports, Volume 11, Issue 7, July 2023., 2023 Abstract Here we report a case of lead poisoning having a serum lead level of 412 mcg dL−1 who presented with decreasing level of consciousness and recurrent seizures. He responded well to treatment with chelation therapy.
Farnoosh Masbough +5 more
wiley +1 more source
From Radiocopper to Cold Copper: Mechanistic Modeling and Simulation to Define Clinical Response Criteria and Biomarkers for VTX-801 in Wilson Disease. [PDF]
CPT Pharmacometrics Syst PharmacolABSTRACT We developed a comprehensive, mechanistic model of human copper metabolism to support biomarker qualification for VTX‐801, an adeno‐associated vector‐based gene therapy which is being developed to restore the mutated ATP7B copper transporter gene in Wilson disease (WD). The model integrates physiological copper kinetics with pathophysiological
Lindauer A +3 more
europepmc +2 more sources