Results 101 to 110 of about 185,470 (305)

Catalytic Dimerization of Crotonates

, 2016
A room-temperature dimerization of crotonates into 2-ethylidene-3-methylpentanedioates provides a sustainable route to difunctional monomers for step-growth polymerizations.
Robert M. Waymouth (1325106), Eun Joo Kang (1661926), Nathaniel I. Strong (1661923), James C. A. Flanagan (1661920)   +3 more
core   +1 more source

Molecular Dynamics Simulation of Homo-DNA: The Role of Crystal Packing in Duplex Conformation

Crystals, 2019
The (4′→6′)-linked DNA homolog 2′,3′-dideoxy-β-D-glucopyranosyl nucleic acid (dideoxy-glucose nucleic acid or homo-DNA) exhibits stable self-pairing of the Watson−Crick and reverse-Hoogsteen types, but does not ...
Jonathan H. Sheehan, Jarrod A. Smith, Pradeep S. Pallan, Terry P. Lybrand, Martin Egli   +4 more
doaj   +1 more source

Structural Insights into RNA Dimerization: Motifs, Interfaces and Functions

Molecules, 2020
In comparison with the pervasive use of protein dimers and multimers in all domains of life, functional RNA oligomers have so far rarely been observed in nature.
Charles Bou-Nader, Jinwei Zhang
doaj   +1 more source

Oppositely Charged Single Enzyme Nanogels Form Versatile Coacervates for Efficient Enzyme Cascade Catalysis

Advanced Materials, EarlyView.
Oppositely charged single enzyme nanogels (SENs) phase‐separate into bi‐enzymatic coacervate microdroplets, acting as both scaffold and functional units. By tuning SEN ratios, these coacervates create specific microenvironments that enable selective small‐molecule enrichment and efficient intermediate diffusion.
Andoni Rodriguez‐Abetxuko, Nadia A. Erkamp, Neshat Moslehi, Yannick H. A. Leurs, Lars Paffen, Işil Yeşil Gür, Jana Stojanović, Hugo Brasselet, Laura van der Weel, Ulf Hanefeld, Ilja K. Voets, Jan C. M. van Hest   +11 more
wiley   +1 more source

Regulation of PrPC signaling and processing by dimerization

Frontiers in Cell and Developmental Biology, 2014
The cellular prion protein (PrPC) is a glycosylphosphatidylinositol (GPI)-anchored protein present at the cell surface. PrPC N-terminal moiety is intrinsically disordered and is able to interact with a variety of ligands.
Xavier eRoucou
doaj   +1 more source

Malectin Alleviates Endoplasmic Reticulum Stress in Gestational Diabetes Mellitus via Glycoprotein Quality Control Mechanisms

Advanced Science, EarlyView.
Malectin alleviates high glucose‐induced ER stress and damage in placental trophoblasts, a function dependent on its six critical carbohydrate‐binding residues. In a GDM mouse model, administration of TAT‐Malectin ameliorated hyperglycemia and placental ER stress and prevented fetal macrosomia.
Jiahui Zhu, Yumeng Zhang, Ye Wang, Xiaoyu Zhu, Ailin Yuan, Weijing Yin, Huangmin Yu, Xuemin Pang, Yufeng He, Yuchen Wang, Tong Wang, Yong Li, Yunlong Si   +12 more
wiley   +1 more source

Dimerization-deficient mutant of Stu2 supports normal mitotic spindle formation.

, 2019
A) Exponentially growing stu2-AID cdc20-AID cultures with an ectopically expressed STU2 allele (STU2WT, SBY17369; stu2ccΔ, SBY17371) or without an ectopic allele (no covering allele, SBY17367) that also contained MTW1-3GFP (kinetochore) and SPC42-CFP ...
Rena K. Evans (7465595), Michael J. MacCoss (125430), Luke M. Rice (7465601), Elisabeth A. Geyer (7465598), Matthew P. Miller (2328283), Alex Zelter (1609087), Sue Biggins (280260), Charles L. Asbury (7465604), Trisha N. Davis (5813)   +8 more
core   +1 more source

Preparing a modified and promoted homogeneous titanium catalyst for ethylene dimerization to butene-1 [PDF]

Polyolefins Journal
Ethylene dimerization is a significant process among the other petrochemical processes due to the production of alpha olefins as the most widely used industrial intermediate.
Sajjad Bahrami Reyhan, Seyed Mahdi Alavi, Davood Soudbar   +2 more
doaj   +1 more source

Transient Dimers of Allergens

PLoS ONE, 2010
Allergen-mediated cross-linking of IgE antibodies bound to the FcepsilonRI receptors on the mast cell surface is the key feature of the type I allergy. If an allergen is a homodimer, its allergenicity is enhanced because it would only need one type of antibody, instead of two, for cross-linking.An analysis of 55 crystal structures of allergens showed ...
Rouvinen, Juha, Jänis, Janne, Laukkanen, Marja-Leena, Jylhä, Sirpa, Niemi, Merja, Päivinen, Tero, Mäkinen-Kiljunen, Soili, Haahtela, Tari, Söderlund, Hans, Takkinen, Kristiina   +10 more
openaire   +7 more sources

Detection of Protein–Protein Interactions in Escherichia coli With Single Molecule Sensitivity

Advanced Science, EarlyView.
This article describes a regulatory circuit in Escherichia coli able to detect protein–protein interactions with exquisite sensitivity. The interaction between two hybrid proteins fused to Bordetella pertussis adenylate cyclase and its activator calmodulin triggers a potent cyclic AMP signaling cascade.
Marilyne Davi, Daniel Ladant
wiley   +1 more source