Results 91 to 100 of about 197,285 (307)

Is there reversible dimerization of albumin in blood plasma? And does it matter? [PDF]

Most albumin in blood plasma is thought to be monomeric with some 5% covalently dimerized. However, many reports in the recent biophysics literature find that albumin is reversibly dimerized or even oligomerized.
Scott, David J., Bradshaw, Michelle L., David J. Halsall, David J. Scott, Norden, Anthony G. W., Robert J. Unwin, Anthony G. W. Norden, Gemma Harris, Michelle L. Bradshaw, Halsall, David J., Harris, Gemma, Unwin, Robert J.   +11 more
core   +1 more source

Lipopolysaccharide uptake is augmented in lipopolysaccharide‐tolerant mouse macrophage‐like cells via increased CD14 expression

FEBS Open Bio, EarlyView.
In normal (nontolerant) cells, CD14 is crucial for both LPS uptake and LPS signaling. In LPS‐tolerant cells, in which LPS‐induced TNF‐α and IFN‐β production is suppressed, there is a dramatic increase in surface CD14 expression. The overexpressed CD14 in LPS‐tolerant cells is responsible for the enhanced LPS uptake without inducing pro‐inflammatory ...
Saeka Nishihara, Takayuki Manabe, Mika Jouta, Kiyoshi Kawasaki   +3 more
wiley   +1 more source

Molecular characterization of covRS mutations in M1UK Streptococcus pyogenes

FEBS Open Bio, EarlyView.
Group A Streptococcus (GAS) acquires covRS mutations driving a hypervirulent bacterial state, frequently associated with invasive disease‐like necrotizing fasciitis. We demonstrate that the newly emerged M1UK GAS lineage can also acquire these mutations.
Jarrad Pritchard, Emma‐Jayne Proctor, Jiawa Wang, Nikolas P. Johnston, Andrew Hayes, Georgia McCorkell, Haibo Yu, Jai Tree, Mark R. Davies, Mark J. Walker, Ronald Sluyter, Stephan Brouwer, Martina L. Sanderson‐Smith   +12 more
wiley   +1 more source

Inhibition of Homophilic Interactions and Ligand Binding of the Receptor for Advanced Glycation End Products by Heparin and Heparin-Related Carbohydrate Structures

Medicines, 2018
Background: Heparin and heparin-related sulphated carbohydrates inhibit ligand binding of the receptor for advanced glycation end products (RAGE). Here, we have studied the ability of heparin to inhibit homophilic interactions of RAGE in living cells and
Ari Rouhiainen, Niko-Petteri Nykänen, Juha Kuja-Panula, Päivi Vanttola, Henri J. Huttunen, Heikki Rauvala   +5 more
doaj   +1 more source

The Influence of the Mixed DPC:SDS Micelle on the Structure and Oligomerization Process of the Human Cystatin C

Membranes, 2020
Human cystatin C (hCC), a member of the superfamily of papain-like cysteine protease inhibitors, is the most widespread cystatin in human body fluids. Physiologically active hCC is a monomer, which dimerization and oligomerization lead to the formation ...
Przemyslaw Jurczak, Emilia Sikorska, Paulina Czaplewska, Sylwia Rodziewicz-Motowidlo, Igor Zhukov, Aneta Szymanska   +5 more
doaj   +1 more source

Dimers, tilings and trees

Journal of Combinatorial Theory, Series B, 2004
Generalizing results of Temperley, Brooks, Smith, Stone and Tutte and others we describe a natural equivalence between three planar objects: weighted bipartite planar graphs; planar Markov chains; and tilings with convex polygons. This equivalence provides a measure-preserving bijection between dimer coverings of a weighted bipartite planar graph and ...
Richard W. Kenyon, Scott Sheffield
openaire   +3 more sources

Structural Basis for Vertebrate Filamin Dimerization [PDF]

, 2005
SummaryFilamins are essential in cell motility and many developmental processes. They are large actin cross linking proteins that contain actin binding domains in their N termini and a long rod region constructed from 24 tandem Ig domains.
P. Jonathan G. Butler, Jari Ylänne, Butler, P. Jonathan G., Ylänne, Jari, Tiila-Riikka Kiema, Stewart, Murray, Kiema, Tiila-Riikka, Murray Stewart, Pudas, Regina, Regina Pudas   +9 more
core   +1 more source

Purification and preparation of Marchantia polymorpha Auxin Response Factor 2 for phase separation studies

FEBS Open Bio, EarlyView.
We describe detailed protocols for the purification and preparation of Marchantia polymorpha Auxin Response Factor 2 (MpARF2). This protein is fused to an MBP solubility tag and an mNG fluorescent tag and is purified from Escherichia coli. The presented procedures make it possible to study MpARF2 assemblies, which could arise from phase separation ...
Bas Janssen, Robin Romein, Willy A. M. van den Berg, Simon Lindhoud, Jan Willem Borst, Carlo P. M. van Mierlo   +5 more
wiley   +1 more source

Dimers of Ethanol

The Journal of Physical Chemistry A, 2004
The energy difference between the gauche and trans structures of ethanol is determined at the CCSD(T)/aug-cc-pVTZ level. Five classes of dimer structures exist due to the two monomer conformations. In a systematic way 600 structures were generated as initial structures for the dimer geometry optimization.
openaire   +2 more sources

Catalytic Dimerization of Crotonates

, 2016
A room-temperature dimerization of crotonates into 2-ethylidene-3-methylpentanedioates provides a sustainable route to difunctional monomers for step-growth polymerizations.
Robert M. Waymouth (1325106), Eun Joo Kang (1661926), Nathaniel I. Strong (1661923), James C. A. Flanagan (1661920)   +3 more
core   +1 more source