Results 71 to 80 of about 197,285 (307)

Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding

FEBS Letters, EarlyView.
In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança, Eline L. Jansen, Jorine M. Eeftens   +2 more
wiley   +1 more source

HpFBH3 transactivates HpCO7 via binding to the E-boxes in the promoter and may accelerate flower formation in pitaya

Journal of Integrative Agriculture
Hylocereus polyrhizus, also known as pitaya or dragon fruit, is a climbing cactus grown worldwide because of its excellent performance under drought stress and appealing red-purple fruits.
Xiaowei Cai, Ling Xiao, Xiangmei Nie, Qiandong Hou, Sulin Wen, Kun Yang, Xiaopeng Wen   +6 more
doaj   +1 more source

Visualizing Rous Sarcoma Virus Genomic RNA Dimerization in the Nucleus, Cytoplasm, and at the Plasma Membrane

Viruses, 2021
Retroviruses are unique in that they package their RNA genomes as non-covalently linked dimers. Failure to dimerize their genomes results in decreased infectivity and reduced packaging of genomic RNA into virus particles.
Eunice C. Chen, Rebecca J. Kaddis Maldonado, Leslie J. Parent   +2 more
doaj   +1 more source

‘Guide and Prejudice’— How Argonautes recognize targets across domains of life

FEBS Letters, EarlyView.
Argonaute proteins use short nucleic‐acid guides to locate and regulate specific targets across all domains of life. Despite striking diversity—from human gene silencing to bacterial immune defence—all Argonautes share a conserved three‐stage recognition logic: guide‐directed sampling, progressive target pairing with a conformational checkpoint and ...
Jack P. K. Bravo
wiley   +1 more source

Dimerization of ADAR1 modulates site-specificity of RNA editing

Nature Communications
Adenosine-to-inosine editing is catalyzed by adenosine deaminases acting on RNA (ADARs) in double-stranded RNA (dsRNA) regions. Although three ADARs exist in mammals, ADAR1 is responsible for the vast majority of the editing events and acts on thousands ...
Allegra Mboukou, Vinod Rajendra, Serafina Messmer, Therese C. Mandl, Marjorie Catala, Carine Tisné, Michael F. Jantsch, Pierre Barraud   +7 more
doaj   +1 more source

Investigating the Functional Role of the Cysteine Residue in Dehydrin from the Arctic Mouse-Ear Chickweed Cerastium arcticum

Molecules, 2022
The stress-responsive, SK5 subclass, dehydrin gene, CaDHN, has been identified from the Arctic mouse-ear chickweed Cerastium arcticum. CaDHN contains an unusual single cysteine residue (Cys143), which can form intermolecular disulfide bonds.
Il-Sup Kim, Woong Choi, Ae Kyung Park, Hyun Kim, Jonghyeon Son, Jun Hyuck Lee, Seung Chul Shin, T. Doohun Kim, Han-Woo Kim   +8 more
doaj   +1 more source

Dynamics of a Bouncing Dimer [PDF]

Physical Review Letters, 2005
4 pages, 5 figures, Movies: http://physics.clarku.edu/~akudrolli ...
Dorbolo, Stéphane, Volfson, D., Tsimring, L., Kudrolli, A.   +3 more
openaire   +4 more sources

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

Molecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan, Veronika M Metzler, Simone de Brot, Corinne L Woodcock, Anna E Harris, Jennifer Lothion‐Roy, Emeli M Nilsson, Atara Ntekim, Michael S Toss, Jenny L Persson, Francesca Khani, Brian D Robinson, Lorraine J Gudas, Emad Rakha, David M Heery, Catrin S Rutland, Nigel P Mongan   +16 more
wiley   +1 more source

Electron-beam-promoted fullerene dimerization in nanotubes: insights from DFT computations

Beilstein Journal of Organic Chemistry
Fullerene dimerization inside a peapod is analyzed at DFT level by characterizing the stationary points and deriving the energy profile of the initial and reversible process named phase 1.
Laura Abella, Gerard Novell-Leruth, Josep M. Ricart, Josep M. Poblet, Antonio Rodríguez-Fortea   +4 more
doaj   +1 more source

Structural view of dimerization interfaces.

, 2015
A) The canonical dimer (blue and green) found in the asymmetric unit. Two dimerization helices (α8, α9 and α8’, α9’) that form four helix bundle at the interface are shown.
Appu Kumar Singh (132960), Abhishek Kaushik (734354), Vijay Singh (1439023), Mary Krishna Ekka (734355), S. Kumaran (132965), Balasubramani GL (734352), Babu Manjasetty (734351), Sukirte Koul (734353)   +7 more
core   +1 more source