Results 61 to 70 of about 197,285 (307)
Metalloporphines: Dimers and Trimers [PDF]
Inorganic Chemistry, 2016 Procedures for the purification and subsequent crystallization of the slightly soluble four-coordinate metallporphines, the simplest possible porphyrin derivatives, are described. Crystals of the porphine derivatives of cobalt(II), copper(II), platinum(II), and two polymorphs of zinc(II) were obtained.
Jentzen, Walter +2 more
openaire +3 more sources
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
FEBS Letters, EarlyView.Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
Zerumbone Inhibits Helicobacter pylori Urease Activity
Molecules, 2021 Helicobacter pylori (H. pylori) produces urease in order to improve its settlement and growth in the human gastric epithelium. Urease inhibitors likely represent potentially powerful therapeutics for treating H.
Hyun Jun Woo +4 more
doaj +1 more source
Merlin isoform 2 dimerization.
, 2023 A). Merlin isoform dimerization reactions with Merlin isoform 1-NL: Merlin isoform 1-GFP, Merlin isoform 2-NL: Merlin isoform 1-GFP and Merlin isoform 2-NL: Merlin isoform 2-GFP.
Nancy Ratner (375065) +4 more
core +1 more source
Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry
FEBS Letters, EarlyView.EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri +5 more
wiley +1 more source
Dimerizing hard spherocylinders in porous media
Condensed Matter PhysicsThis research focuses on the unique phase behavior of non-spherical patchy colloids in porous environments. Based on the theory of scaled particle (SPT), methods have been refined and applied to analyze the thermodynamic properties of non-spherical ...
V. I. Shmotolokha, M. F. Holovko
doaj +1 more source
Journal of Lipid Research, 2013 Thromboxane A2 (TXA2) contributes to cardiovascular disease (CVD) by activating platelets and vascular constriction and proliferation. Despite their preclinical efficacy, pharmacological antagonists of the TXA2 receptor (TP), a G protein-coupled receptor,
Alexander J. Frey +4 more
doaj +1 more source
Predictions of the dimerization and autoproteolysis using sequence profile analysis [PDF]
, 2009 [[abstract]]Protein fold recognition using sequence profile searches frequently allows prediction of the structure and biochemical mechanisms of proteins with an important biological function but unknown biochemical activity. In this present, we describe
Ping-Hsi Liao(廖平喜); Te-Hsiang Chen(陳德祥);Shang-Fang Lee(李尚凡);Pei-Yu Liao(廖珮妤)
core
Dimerization contacts of LftR.
, 2019 One LftR subunit is shown as gray ribbons with surface representation, and its dimerization interface residues are highlighted by cyan surfaces and sticks.
Jaewan Park (6577037) +3 more
core +1 more source
Temperature-Dependent Spin-Driven Dimerization Determines the Ultrafast Dynamics of a Copper(II)-Bound Tripyrrindione Radical [PDF]
, 2023 Radicals and other open-shell molecules play a central role in chemical transformations and redox chemistry. While radicals are often highly reactive, stable radical systems are desirable for a range of potential applications ranging from materials ...
Vanessa, Huxter +4 more
core +2 more sources