Results 61 to 70 of about 295,838 (293)

Calpain small subunit homodimerization is robust and calcium‐independent

FEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy, Trina Dykstra‐MacPherson, Mathias A. Bell, Peter L. Davies, Ruby May A. Sullan   +4 more
wiley   +1 more source

Electron-beam-promoted fullerene dimerization in nanotubes: insights from DFT computations

Beilstein Journal of Organic Chemistry
Fullerene dimerization inside a peapod is analyzed at DFT level by characterizing the stationary points and deriving the energy profile of the initial and reversible process named phase 1.
Laura Abella, Gerard Novell-Leruth, Josep M. Ricart, Josep M. Poblet, Antonio Rodríguez-Fortea   +4 more
doaj   +1 more source

Mass ratio of elementary excitations in frustrated antiferromagnetic chains with dimerization

, 2012
Excitation spectra of S=1/2 and S=1 frustrated Heisenberg antiferromagnetic chains with bond alternation (explicit dimerization) are studied using a combination of analytical and numerical methods.
Masaki Oshikawa, Shintaro Takayoshi, T. Giamarchi   +2 more
core   +1 more source

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

FEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source

Synthesis and Characterization of Dimeric Artesunate Glycerol Monocaprylate Conjugate and Formulation of Nanoemulsion Preconcentrate

Molecules, 2023
Malaria is one of the major life-threatening health problems worldwide. Artesunate is the most potent antimalarial drug to combat severe malaria. However, development of drug resistance, short plasma half-life, and poor bioavailability limit the efficacy
Rana Hore, Nazmul Hasan, Karsten Mäder, Jörg Kressler   +3 more
doaj   +1 more source

Basic properties of three-leg Heisenberg tube

, 2008
We study three-leg antiferromagnetic Heisenberg model with the periodic boundary conditions in the rung direction. Since the rungs form regular triangles, spin frustration is induced.
Citro R, Dagotto E, Gogolin A O, Mitsuhiro Arikawa, Sakai T, Satoshi Nishimoto, Schulz H J   +6 more
core   +1 more source

Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma

Molecular Oncology, EarlyView.
Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken, Andrea Abel Gutierrez, Imke van Rossum, Cornelia G. Spruijt, Michiel Vermeulen, Guido van Mierlo, Blanca Scheijen, Annemiek B. van Spriel   +7 more
wiley   +1 more source

Interaction induced dimerization in zigzag single wall carbon nanotubes

, 2007
We derive a low-energy effective model of metallic zigzag carbon nanotubes at half filling. We show that there are three important features characterizing the low-energy properties of these systems: the long-range Coulomb interaction, umklapp scattering ...
A. O. Gogolin, Alexander A. Nersesyan, Alexander O. Gogolin, P. Di Francesco, R. Saito, Sam T. Carr   +5 more
core   +1 more source

Recurrent cancer‐associated ERBB4 mutations are transforming and confer resistance to targeted therapies

Molecular Oncology, EarlyView.
We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala, Sini Ahonen, Sara Peltola, Aura Tuohisto‐Kokko, Olaya Esparta, Peppi Suominen, Anne Jokilammi, Iman Farahani, Deepankar Chakroborty, Nikol Dibus, Steffen Boettcher, Tomi T. Airenne, Mark S. Johnson, Lisa D. Eli, Klaus Elenius, Kari J. Kurppa   +15 more
wiley   +1 more source

A chiral spin liquid wave function and the Lieb-Schulz-Mattis theorem

, 2003
We study a chiral spin liquid wave function defined as a Gutwziller projected BCS state with a complex pairing function. After projection, spontaneous dimerization is found for any odd but finite number of chains, thus satisfying the Lieb-Schultz-Mattis ...
Alberto Parola, C. K. Majumdar, C. K. Majumdar, E. Dagotto, E. H. Lieb, Federico Becca, I. Affleck, Luca Capriotti, M. E. Fisher, P. W. Anderson, Sandro Sorella   +10 more
core   +1 more source