Results 51 to 60 of about 185,470 (305)
, 2022 Metal–organic frameworks (MOFs) with metal nodes and organic linkers have significant potential as reaction catalysts. However, one major factor impeding the development and use of MOFs as organic reaction catalysts is the detailed under-standing of ...
Daniel, Ess +4 more
core +1 more source
CENP-A Ubiquitylation Contributes to Maintaining the Chromosomal Location of the Centromere
Molecules, 2019 The centromere plays an essential role in accurate chromosome segregation, and the chromosomal location of the centromere is determined by the presence of a histone H3 variant, centromere protein A (CENP-A), in centromeric nucleosomes.
Yohei Niikura, +2 more
doaj +1 more source
Calpain small subunit homodimerization is robust and calcium‐independent
FEBS Letters, EarlyView.Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source
The Contribution of Different Androgen Receptor Domains to Receptor Dimerization and Signaling
, 2008 The androgen receptor (AR) is a ligand-activated transcription factor of the nuclear receptor superfamily that plays a critical role in male physiology and pathology.
Centenera, Margaret M. +11 more
core +1 more source
Pd(OAc)2/Ph3P-catalyzed dimerization of isoprene and synthesis of monoterpenic heterocycles
Beilstein Journal of Organic Chemistry, 2017 The palladium-catalyzed dimerization of isoprene is a practical approach of synthesizing monoterpenes. Though several highly selective methods have been reported, most of them still required pressure or costly ligands for attaining the active system and ...
Dominik Kellner +3 more
doaj +1 more source
VEGFR-2 conformational switch in response to ligand binding
eLife, 2016 VEGFR-2 is the primary regulator of angiogenesis, the development of new blood vessels from pre-existing ones. VEGFR-2 has been hypothesized to be monomeric in the absence of bound ligand, and to undergo dimerization and activation only upon ligand ...
Sarvenaz Sarabipour +2 more
doaj +1 more source
FEBS Letters, EarlyView.Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley +1 more source
Synthesis of Butenolides via a Horner-Wadsworth-Emmons Cascading Dimerization Reaction
, 2019 The efficient synthesis of a range of structurally related butenolides has been observed while we were exploring the substrate-scope of a Horner–Wadsworth–Emmons (HWE) reaction.
Everson, Jack, Kiefel, Milton J
core +1 more source
, 2021 The plasmon-driven dimerization of 4-nitrothiophenol (4NTP) to 4-4’-dimercaptoazobenzene (DMAB) has become a testbed for understanding bimolecular photoreactions enhanced by nanoscale metals, in particular, regarding the relevance of electron transfer ...
Matias, Bargheer +14 more
core +1 more source
Zerumbone Inhibits Helicobacter pylori Urease Activity
Molecules, 2021 Helicobacter pylori (H. pylori) produces urease in order to improve its settlement and growth in the human gastric epithelium. Urease inhibitors likely represent potentially powerful therapeutics for treating H.
Hyun Jun Woo +4 more
doaj +1 more source