Results 41 to 50 of about 58,800 (302)

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source

TiO2 nanofibers of different crystal phases for transesterification of alcohols with dimethyl carbonate

, 2014
TiO2 nanofibers with different crystal phases have been discovered to be efficient catalysts for the transesterification of alcohols with dimethyl carbonate to produce corresponding methyl carbonates. Advantages of this catalytic system include excellent
Liu, Hongwei, Ke, Xuebin, Zheng, Zhanfeng, Zhu, Huaiyong, Zhang, Xingguang   +4 more
core   +1 more source

Acute caffeine treatment protects the developing retina from ischemia‐induced cell death

FEBS Open Bio, EarlyView.
Caffeine reduces cell death in the developing retina under ischemia (OGD). This effect does not involve BDNF upregulation or antioxidant pathways (NRF2/VEGF). Neuroprotection occurs mainly through adenosine A2A receptor antagonism, decreasing glutamate release and excitotoxicity, highlighting caffeine's potential as an acute neuroprotective agent in ...
Amanda Alves Nascimento, Danniel Pereira‐Figueiredo, Gabriella Grossi de Lima Dias, Gabriel Ferreira dos Santos, Mariana Rodrigues Pereira, Rafael Brito, Karin C Calaza   +6 more
wiley   +1 more source

Dimethyl carbonate synthesis from CO2 and methanol over CeO2-ZrO2 catalyst

Catalysis Communications, 2022
CexZr1-xO2 catalysts with different Ce/Zr mole ratios were prepared by the sol-gel method and used for the direct synthesis of dimethyl carbonate (DMC) from CO2 and methanol.
Shiyu Xu, Yunxia Cao, Zhiming Liu
doaj   +1 more source

Pharmacological inhibition of the PERK pathway modulates hepatocellular carcinoma growth and immune signaling

FEBS Open Bio, EarlyView.
Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero, Maria Kopsida, Nathalie Arendt, Hans Lennernäs, Markus Sjöblom, Femke Heindryckx   +5 more
wiley   +1 more source

Mechanistic Study of Substituent Effect on Photoinduced O-C Bond Activation in Polycarbonate

Molecules
Photodegradation of polycarbonate (PC) is investigated based on quantum chemical methods with PC models to clarify the effect of substituents at different positions of phenyl rings on the carbonate O-C bond cleavage.
Xiao Huang, Yuuichi Orimoto, Yuriko Aoki
doaj   +1 more source

A New Approach to Environmentally Friendly Protein Plastics and Foams

BioResources, 2015
New formaldehyde-free and isocyanate-free bioplastics and biofoams were prepared by reacting ovoalbumin and dimethyl carbonate (DMC) at a moderate temperature.
María Cecilia Basso, Antonio Pizzi, Luc Delmotte   +2 more
doaj   +1 more source

Investigating the reaction mechanism of dimethyl carbonate synthesis through isotopic labeling experiments

Catalysis Communications, 2023
The synthesis of dimethyl carbonate (DMC) from carbon dioxide and methanol was studied over a ceria- zirconia mixed metal oxide. When using oxygen-18 labeled ceria-zirconia, no oxygen-18 labeled DMC or water was observed.
Cécile Daniel, David Farrusseng, Yves Schuurman   +2 more
doaj   +1 more source

Sudden anaerobization in Amphibacillus xylanus increases intracellular labile ferrous iron and inhibits cell growth

FEBS Open Bio, EarlyView.
Abruptly changing from aerobic to anaerobic conditions (sudden anaerobization) induced growth inhibition and a significant increase in intracellular labile ferrous iron in the aerotolerant anaerobe Amphibacillus xylanus. We found that free flavins mediate efficient electron transfer from NADH to ferric iron under anaerobic conditions, suggesting that ...
Shinya Kimata, Yoichi Sakai, Keisuke Tanaka, Etsuro Yoshimura, Ken Kitano, Morio Ishikawa, Tadahiro Nakamoto, Tsutomu Takayama, Hirofumi Inoue, Kaho Nomura, Tomonori Suzuki, Masataka Uchino, Akira Abe, Youichi Niimura   +13 more
wiley   +1 more source

Redox-neutral electrochemical conversion of CO2 to dimethyl carbonate

, 2021
Electrochemical reduction of CO2 can generate fuel precursors and additives, yet the set of possible products and overall efficiency are limited. Now, Lee et al.
Lee, Kyu Min, Kim, Jeong Eun, Jang, Jun Ho, Jo, Young In, Nam, Ki Tae, Balamurugan, Mani   +5 more
core   +1 more source