T Helper Cells: The Modulators of Inflammation in Multiple Sclerosis [PDF]
Multiple sclerosis (MS) is a chronic neurodegenerative disease characterized by the progressive loss of axonal myelin in several areas of the central nervous system (CNS) that is responsible for clinical symptoms such as muscle spasms, optic neuritis ...
Amormino, Carola +4 more
core +1 more source
Patients monitoring during treatment with Dimethyl fumarate (ORP-23) [PDF]
Dimethyl Fumarate (DMF) is a methyl ester of fumaric acid (chemical formula C6H8O4) that is hydrolyzed in the small intestine to the active metabolite monomethyl fumarate, approved for the treatment of RMS, and moderate to severe Psoriasis.
Ali Yousefi Pour
doaj
A functional description of CymA, an electron-transfer hub supporting anaerobic respiratory flexibility in Shewanella [PDF]
CymA (tetrahaem cytochrome c) is a member of the NapC/NirT family of quinol dehydrogenases. Essential for the anaerobic respiratory flexibility of shewanellae, CymA transfers electrons from menaquinol to various dedicated systems for the reduction of ...
Butt, Julea N. +10 more
core +1 more source
A Bibliometric Evaluation of the Top 100 Cited Dimethyl Fumarate Articles
Dimethyl fumarate is a cytoprotective and immunomodulatory drug used in the treatment of multiple sclerosis. We performed a bibliometric study examining the characteristics and trends of the top 100 cited articles that include dimethyl fumarate in the ...
Francisco Javier García-Fernández +6 more
doaj +1 more source
Pharmacology and clinical drug candidates in redox medicine [PDF]
SIGNIFICANCE Oxidative stress is suggested to be a disease mechanism common to a wide range of disorders affecting human health. However, so far, the pharmacotherapeutic exploitation of this, for example, based on chemical scavenging of pro-oxidant ...
Casas, Ana I +11 more
core +3 more sources
Glutathione Metabolism in Renal Cell Carcinoma Progression and Implications for Therapies [PDF]
A significantly increased level of the reactive oxygen species (ROS) scavenger glutathione (GSH) has been identified as a hallmark of renal cell carcinoma (RCC). The proposed mechanism for increased GSH levels is to counteract damaging ROS to sustain the
Meierhofer, David, Xiao, Yi
core +2 more sources
Decomposition of Bayer process organics: Phenolates, polyalcohols, and additional carboxylates [PDF]
The degradation of nineteen low-molecular-weight phenolates, polyalcohols and selected aliphatic and aromatic carboxylates of relevance to the Bayer process has been studied in 6 mol kg-1 NaOH(aq) at 90 °C for up to 36 days, and (for some species) at 180
Hefter, G.T. +4 more
core +2 more sources
Dimethyl Fumarate Treatment in Patients with Moderate-to-Severe Psoriasis: A 52-week Real-life Study
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Laura Gnesotto +17 more
doaj +1 more source
Trispyrazolylborate Ligands Supported on Vinyl Addition Polynorbornenes and Their Copper Derivatives as Recyclable Catalysts [PDF]
Polynorbornenes prepared by vinyl addition poly- merization and bearing pendant alkenyl groups serve as skeletons to support trispyrazolylborate ligands (Tpx) built at those alkenyl sites.
Albéniz Jiménez, Ana Carmen +6 more
core +2 more sources
Successful management of bullous pemphigoid with dimethyl fumarate therapy: A case report
A 69-year-old woman affected by multiple sclerosis for 35 years was diagnosed with bullous pemphigoid (BP) and treated successfully with dimethyl fumarate (DMF) at a dose of 120 mg twice per day for 7 days and then increased to 240 mg twice per day after
Aslı Bilgic-Temel, MD +2 more
doaj +1 more source

