Results 51 to 60 of about 140,776 (178)

Evaluation of Dried Plasma Spot‐Based Quantification of Glial Fibrillary Acidic Protein as a Disease‐Associated Biomarker in Neuromyelitis Optica Spectrum Disorder

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To evaluate the diagnostic accuracy of glial fibrillary acidic protein (GFAP) measured in dried plasma spots versus conventional plasma‐ and serum‐GFAP testing for assessment of disease severity in aquaporin‐4 immunoglobulin G–positive neuromyelitis optica spectrum disorder (AQP4‐IgG+ NMOSD).
Felix Wohlrab, Evelyn Alvarez, Roua Hamdi, Bingqing Zhang, Hayeun Ji, Niyati Jhaveri, Patrick Schindler, Pedro Sanchez, Pia S. Sperber, Tanja Schmitz‐Hübsch, Frederike C. Oertel, Nisa Vorasoot, Najib Kissani, Falko Böhringer, Jens Kuhle, Anne‐Katrin Pröbstel, Xiao‐Jun Ma, Péter Körtvelyessy, Patrick Waters, Friedemann Paul   +19 more
wiley   +1 more source

Dimethyl Fumarate: A Review in Relapsing-Remitting MS

, 2019
Compliance with Ethical Standards Funding The preparation of this review was not supported by any external funding. Conflicts of interest Hannah Blair is a salaried employee of Adis International Ltd/Springer Nature, is responsible for the article ...
Hannah A. Blair (5008301)
core   +1 more source

Degradable Alternating Copolymers With Strained Cyclobutane Backbones via Photocontrolled RAFT Polymerization

Angewandte Chemie, EarlyView.
A photocontrolled RAFT strategy enables the alternating copolymerization of 1,3‐disubstituted bicyclo[1.1.0]butanes with electron‐deficient comonomers, affording well‐defined copolymers bearing strained cyclobutane backbones. A high degree of alternation, tunable molecular weights, and excellent end‐group fidelity are achieved through a CTA‐mediated ...
Xia Hu, Hongsik Kim, Lianqian Wu, Yi Jiang, Tae‐Lim Choi   +4 more
wiley   +2 more sources

Decoding Synergistic Pathways in Bimetallic MOFs for Advanced Oxidation Processes

Advanced Materials, EarlyView.
This review presents a unified framework linking metal pairing and framework design with electronic structure, redox cycling, oxidant activation, reactive‐species generation, and catalytic performance across photocatalytic and oxidant‐based BMOF‐AOPs. The resulting design principles guide the development of hydrolytically stable and efficient BMOFs for
Karim El‐Naggar, Huayang Zhang, Shaobin Wang   +2 more
wiley   +1 more source

Alopecia areata treated with dimethyl fumarate: a case series

, 2020
Alopecia areata is an autoimmune condition leading to non-scarring hair loss. Clinically, several presentations ranging from single or few small patches to complete hair loss are documented.
Alfredo Rossi, Gemma Caro, Maria Caterina Fortuna, Francesca Magri, Marta Muscianese, Pier Paolo Leoncini   +5 more
core   +1 more source

Fumarate analogs act as allosteric inhibitors of the human mitochondrial NAD(P)+-dependent malic enzyme. [PDF]

PLoS ONE, 2014
Human mitochondrial NAD(P)+-dependent malic enzyme (m-NAD(P)-ME) is allosterically activated by the four-carbon trans dicarboxylic acid, fumarate. Previous studies have suggested that the dicarboxylic acid in a trans conformation around the carbon-carbon
Ju-Yi Hsieh, Jyung-Hurng Liu, Pai-Chun Yang, Chi-Li Lin, Guang-Yaw Liu, Hui-Chih Hung   +5 more
doaj   +1 more source

Tailored Stereo‐Configuration of Crosslinkable Polyester‐Based Solid Polymer Electrolytes for All‐Solid‐State and Binder‐Free Li Metal Batteries

Advanced Science, EarlyView.
Variations in polymer conformations of unsaturated poly(n‐alkyl esters) driven by monomer‐level stereochemistry directly govern Li+ solvation structures in polymer host matrices. The synergistic strategies of polymer conformation control, UV‐induced interchain crosslinking, and end‐group fluorination are implemented for engineering advanced solid ...
Hyun Jun Song, Jeong Yoon Kim, Sungpyo Hong, Yong Hui Kim, Myeong Gyun Nam, Jeong‐Won Ho, Min Gi Kang, Hye Seon Kim, Chaeyeon Ha, Sang Uck Lee, Pil J. Yoo, Patrice Rannou   +11 more
wiley   +1 more source

Comparison of fingolimod, dimethyl fumarate and teriflunomide for multiple sclerosis

, 2019
Objective: Oral immunotherapies have become a standard treatment in relapsing-remitting multiple sclerosis. Direct comparison of their effect on relapse and disability is needed.
Pucci, Eugenio, Kubala Havrdova, Eva, Ozakbas, Serkan, Kuhle, Jens, McCombe, Pamela A, Ferraro, Diana, Izquierdo, Guillermo, Van Wijmeersch, Bart, Lechner-Scott, Jeannette, Granella, Franco, Bergamaschi, Roberto, Onofrj, Marco, Boz, Cavit, Prat, Alexandre, Girard, Marc, Turkoglu, Recai, Solaro, Claudio, Grand'Maison, Francois, Duquette, Pierre, Lugaresi, Alessandra, Terzi, Murat, Slee, Mark, Kappos, Ludwig, Prevost, Julie, Pesch, Vincent Van, Trojano, Maria, Grammond, Pierre, Kalincik, Tomas, Horakova, Dana, Sola, Patrizia, Ramo-Tello, Cristina   +30 more
core   +1 more source

Dimethyl Fumarate Treatment in Patients With Primary Progressive Multiple Sclerosis:A Randomized, Controlled Trial

, 2021
BACKGROUND AND OBJECTIVE: To study whether dimethyl fumarate is superior to placebo in decreasing CSF concentrations of neurofilament light chain (NFL) in patients with primary progressive MS (PPMS). METHODS: In the double-blind, placebo-controlled phase
Lange, Theis, Blinkenberg, Morten, Højsgaard Chow, Helene, Talbot, Jacob, Soelberg Sørensen, Per, Gøbel Madsen, Camilla, Siebner, Hartwig Roman, Mahler, Mie Reith, Holm Hansen, Rikke, Sellebjerg, Finn, Rode von Essen, Marina, Marstrand, Lisbet, Buhelt, Sophie, Romme Christensen, Jeppe, Lundell, Henrik   +14 more
core   +1 more source

CA9‐Targeted PET Imaging for Noninvasive Discrimination of Clear Cell Renal Cell Carcinoma and Associated Tumor Biological Features

Advanced Science, EarlyView.
CA9‐targeted PET imaging could be a noninvasive approach to characterize clear cell renal cell carcinoma and associated tumor biology. PET uptake correlates with tumor CA9 expression and is linked to angiogenic activity, immune remodeling, and metabolic reprogramming.
Kailei Chen, Sixuan Cheng, Jian Shi, Ruijie Liu, Yilong Wu, Xin Zheng, Xinlun Song, Yunxuan Zhang, Lei Liu, Zhihao Wei, Qi Wang, Xinwei Li, Zirui Dong, Yuenan Liu, Hongmei Yang, Xiaoli Lan, Chunxia Qin, Dawei Jiang, Keshan Wang, Xiaoping Zhang   +19 more
wiley   +1 more source