Results 71 to 80 of about 386,611 (320)

5-Benzoyl-2-(5-bromo-1H-indol-3-yl)-4-(4-nitrophenyl)-1H-pyrrole-3-carbonitrile dimethyl sulfoxide monosolvate

IUCrData, 2016
The title compound, C26H15BrN4O3·C2H6OS, contains five rings. The indole unit is essentially planar [maximum deviation = 0.0067 (1) Å for the N atom]. The central pyrrole ring makes dihedral angles of 44.1 (2) and 51.3 (2)° with the pendant indole ring ...
Y. AaminaNaaz, Jayabal Kamalraja, Paramasivam T. Perumal, A. SubbiahPandi   +3 more
doaj   +1 more source

Evaluation of in vitro toxicity of common phytochemicals included in weight loss supplements using 1H NMR spectroscopy

FEBS Open Bio, EarlyView.
We investigated the toxicity of 12 active compounds commonly found in herbal weight loss supplements (WLS) using human liver and colon cell models. Epigallocatechin‐3‐gallate was the only compound showing significant toxicity. Metabolic profiling revealed protein degradation, disrupted energy and lipid metabolism suggesting that the inclusion of EGCG ...
Emily C. Davies, Garth L. Maker, Ian F. Musgrave, Samantha Lodge   +3 more
wiley   +1 more source

2-[(1-{[3-(dimethylazaniumyl)propyl]methylamino}ethylidene)azaniumyl]nonahydro-closo-decaborate dimethyl sulfoxide disolvate

Acta Crystallographica Section E, 2011
The title compound, 2-B10H9NH=C(CH3)N(CH3)CH2CH2CH2N(CH3)2H·2C2H6OS or C8H29B10N3·2C2H6OS, is zwitterionic with the negative charge localized on the decaborate cage and the positive charge on the terminal ammonium group.
Thomas D. Getman, Rudy L. Luck, Caitlin Cienkus   +2 more
doaj   +1 more source

Me2SO perfusion time for whole-organ cryopreservation can be shortened: Results of micro-computed tomography monitoring during Me2SO perfusion of rat hearts.

PLoS ONE, 2020
Cryopreservation of whole organs and specific tissues is an important and continually expanding field of medicine. The protocols currently used for organ preservation do not ensure survivability and functionality; the protocols for ovarian tissue lead to
Nathalie Bleisinger, Ralf Dittrich, Olga Strahl, Robert Brauweiler, Inge Hoffmann, Matthias W Beckmann, Tilmann Volk   +6 more
doaj   +1 more source

Influence of Sulfoxide Group Placement on Polypeptide Conformational Stability. [PDF]

, 2019
The synthesis of a homologous series containing five new nonionic sulfoxide containing polypeptides was described. Sulfoxide groups bestowed water solubility for all homologues, which allowed their use as a model for study of helix-coil transitions in ...
Bahrun, Ehab, Deming, Timothy J, Gharakhanian, Eric G   +2 more
core  

Anticancer sensitivities and biological characteristics of HCT116 cells resistant to the selective poly(ADP‐ribose) glycohydrolase inhibitor

FEBS Open Bio, EarlyView.
We analyzed alterations of PAR metabolism‐related proteins in PARG inhibitor‐resistant HCT116RPDD cells. Although PARG levels remained unchanged, HCT116RPDD cells exhibited reduced PARP1 and ARH3 expression and elevated PAR levels. Interestingly, HCT116RPDD cells exhibited slightly elevated intracellular NAD+/NADH and ATP levels. Our findings suggest a
Kaede Tsuda, Yoko Ogino, Akira Sato
wiley   +1 more source

4-(5,6-Dihydrobenzimidazo[1,2-c]quinazolin-6-yl)benzene-1,3-diol dimethyl sulfoxide monosolvate

Acta Crystallographica Section E, 2011
In the title solvated benzimidazole compound, C20H15N3O2·C2H6OS, both the benzimidazole fused-ring system and the complete dimethyl sulfoxide solvent molecule are disordered over two sets of sites, in 0.750 (5):0.250 (5) and ...
Naser Eltaher Eltayeb, Siang Guan Teoh, Chin Sing Yeap, Hoong-Kun Fun   +3 more
doaj   +1 more source

Antitumor effect of therapeutic HPV DNA vaccines with chitosan-based nanodelivery systems [PDF]

, 2014
Cervical cancer is the second-most-common cause of malignancies in women worldwide, and the oncogenic activity of the human papilloma virus types (HPV) E7 protein has a crucial role in anogenital tumors.
Atyabi, F., Ghaemi, A., Gorji, A., Kalhor, H.R., Kelishadi, M., Moradi, A., Sajadian, A., Tabarraei, A., Tahamtan, A.   +8 more
core   +3 more sources

Monocyte LOXHD1 and RHOB Expression Predictive of Progressive Systemic Sclerosis–Associated Interstitial Lung Disease

Arthritis Care &Research, EarlyView.
Objective A leading cause of death among patients with scleroderma (SSc), interstitial lung disease (ILD) remains challenging to prognosticate. The discovery of biomarkers that accurately determine which patients would benefit from close monitoring and aggressive therapy would be an essential clinical tool.
Cristina M. Padilla, Robert Lafyatis, Kevin F. Gibson, Christina Morse, Eleanor Valenzi, Xiaoping Chen, Xiaoyun Li, Yanwu Zhao, Yongseok Park, Dana Ascherman, Jonathan Minden, Robyn Domsic, Yingze Zhang, Daniel J. Kass   +13 more
wiley   +1 more source

2,9-Bis(5-sulfanylidene-4,5-dihydro-1,3,4-oxadiazol-2-yl)-1,10-phenanthroline dimethyl sulfoxide disolvate

Acta Crystallographica Section E, 2014
In the title compound, C16H8N6O2S2·2C2H6OS, the phenanthroline molecule resides on a twofold axis, and the asymmetric unit also contains a slightly disordered [occupancy ratio for S atom of 0.95 (3):0.047 (3)] molecule of dimethyl sulfoxide.
Md. A Rahman, Mohammad Karim, Md. Arifuzzaman, Tasneem Siddiquee, Lee M. Daniels   +4 more
doaj   +1 more source