Results 61 to 70 of about 2,210 (158)

Biochemical and Molecular Mechanisms of Platelet-Rich Plasma in Ameliorating Liver Fibrosis Induced by Dimethylnitrosurea

Cellular Physiology and Biochemistry, 2018
Background/Aims: Hepatic fibrosis is a wound-healing process in the chronically injured liver. Clinical application of platelet-rich plasma (PRP) is of considerable interest for wound healing and regeneration.
Neveen A. Salem, Amal Hamza, Hanan Alnahdi, Najla Ayaz   +3 more
doaj   +1 more source

Protective Effect of Soybean Bioactive Compounds on Liver Disorders: A Bibliometric Analysis and Review

Journal of Food Biochemistry, Volume 2025, Issue 1, 2025.
Diet intervention and nutritional support have been accepted as a cornerstone of therapy for various disorders of the liver, a central organ of metabolism and digestion. Epidemiological data have shown the beneficial effects of soy‐containing diets on patients with liver disorders represented by nonalcoholic fatty liver disease (NAFLD), the latter of ...
Xiwei Liu, Yichao Ma, Ziyi Xu, Jun Wang, Mohamed Afifi   +4 more
wiley   +1 more source

Liver cirrhosis: molecular mechanisms and therapeutic interventions

MedComm, Volume 5, Issue 10, October 2024.
This review emphasized the recent applications of different therapeutic strategies that regulate liver fibrosis and liver cirrhosis and highlighted the importance of nanomedicine with an emerging therapist in liver cirrhosis. Abstract Liver cirrhosis is the end‐stage of chronic liver disease, characterized by inflammation, necrosis, advanced fibrosis ...
Zihe Dong, Yeying Wang, Weilin Jin
wiley   +1 more source

Histopathological and biochemical effects of green tea and/or licorice aqueous extracts on thyroid functions in male albino rats intoxicated with dimethylnitrosamine

Nutrition & Metabolism, 2009
Objective To investigate histopathological and biochemical effects of green tea and/or licorice aqueous extracts in thyroid functions in male albino rats intoxicated with Dimethylnitrosamine. Methods 40 Male albino rats were divided into two main groups,
Mohamed U, Bstawi M, El Mgeed A Abd, Gabbar M Abdel   +3 more
doaj   +1 more source

Induction of Dimethylnitrosamine-demethylase by Polar Solvents

Experimental Biology and Medicine, 1980
SummaryThe polar compounds acetone, dioxane, tetrahydrofuran, di-methylsulfoxide, trioctanoin, and polyoxyethylene sorbitan monooleate (Tween 80) induce the activity of hepatic dimethylnitrosamine-demethylase I, a mixed-function oxidase repressed by typi-cal inducer agents such as 3-methylcholanthrene and phenobarbital. The highest activity was reached
M F, Argus, B J, Neuburger, S C, Myers, J C, Arcos   +3 more
openaire   +2 more sources

Novel matrine derivative MD-1 attenuates hepatic fibrosis by inhibiting EGFR activation of hepatic stellate cells

Protein & Cell, 2016
Matrine (MT), the effective component of Sophora flavescens Ait, has been shown to have anti-inflammation, immune-suppressive, anti-tumor, and anti-hepatic fibrosis activities.
Yi Feng, Hai-yan Ying, Ying Qu, Xiao-bo Cai, Ming-yi Xu, Lun-gen Lu   +5 more
doaj   +1 more source

A novel role of glutathione S-transferase A3 in inhibiting hepatic stellate cell activation and rat hepatic fibrosis

Journal of Translational Medicine, 2019
Background and aims Glutathione S-transferase A3 (GSTA3) is known as an antioxidative protease, however, the crucial role of GSTA3 in liver fibrosis remains unclear.
Haihua Chen, Qixin Gan, Congying Yang, Xiongqun Peng, Jiao Qin, Sisi Qiu, Yanzhi Jiang, Sha Tu, Ying He, Shenglan Li, Huixiang Yang, Lijian Tao, Yu Peng   +12 more
doaj   +1 more source

Experimental models for induction of liver cirrhosis in animals: a review [PDF]

Biotemas, 2010
The liver plays a key role in the homeostatic balance of many biological processes. Cirrhosis is a syndrome in which chronic liver diseases converge, leading to hepatocellular injury, the exacerbated deposition of fibrous tissue, and eventually the ...
Cristiane Carlin Passos, Amanda Olivotti Ferreira, Francisco Javier Hernandez Blazquez, Ricardo Romão Guerra   +3 more
doaj  

Characterization of the Roles of Vimentin in Regulating the Proliferation and Migration of HSCs during Hepatic Fibrogenesis

Cells, 2019
The activation of hepatic stellate cells (HSCs) manifested as proliferation and migration is the pivotal event involved in liver fibrogenesis. The vimentin network, an intermediate filament (IF) system, is one of the critical cascades by which the cell ...
Pei-Wen Wang, Tung-Ho Wu, Tung-Yi Lin, Mu-Hong Chen, Chau-Ting Yeh, Tai-Long Pan   +5 more
doaj   +1 more source

Reversal of Experimental Liver Damage after Transplantation of Stem-Derived Cells Detected by FTIR Spectroscopy

Stem Cells International, 2017
The transplantation of autologous BM-MSCs holds great potential for treating end-stage liver diseases. The aim of this study was to compare the efficiency of transplanted rBM-MSCs and rBM-MSC-derived differentiated stem cells (rBM-MSC-DSCs) for ...
Danna Ye, Philip Heraud, Rangsun Parnpai, Tong Li   +3 more
doaj   +1 more source