Results 61 to 70 of about 2,930 (198)
Incilius alvarius Cell-Based Synthesis of 5-Methoxy-N,N-Dimethyltryptamine [PDF]
, 2023 Leonard Lerer +4 more
openalex +1 more source
Evaluation of preclinical antipsychotic models used to support first‐in‐human clinical trials
British Journal of Pharmacology, EarlyView.Abstract Schizophrenia is regarded as a complex and heterogeneous psychiatric disorder, characterised by diverse symptoms and comorbidities, which complicate both clinical management and drug development. Current pharmacological treatment, primarily based on dopamine D2 receptor antagonism or partial agonism, which has not markedly progressed since the
Thi Viet Ha Nguyen +2 more
wiley +1 more source
DMT alters cortical travelling waves
eLife, 2020 Psychedelic drugs are potent modulators of conscious states and therefore powerful tools for investigating their neurobiology. N,N, Dimethyltryptamine (DMT) can rapidly induce an extremely immersive state of consciousness characterized by vivid and ...
Andrea Alamia +4 more
doaj +1 more source
Direct Ambient Mass Spectrometry for Food, Beverage, and Agricultural Sample Analysis and Research
Mass Spectrometry Reviews, Volume 45, Issue 2, Page 429-452, March/April 2026.ABSTRACT Ambient and direct mass spectrometry (MS) methods are becoming increasingly used for the rapid analysis of food, beverage and agricultural samples. Novel ionization approaches combined with targeted, or untargeted workflows provide analytical outcomes within a greatly reduced time period compared to traditional separation science coupled with ...
Leigh M. Schmidtke +3 more
wiley +1 more source
PsychoactivesPsychoactive drugs are compounds that alter the function of the central nervous system, resulting in changes in perception, mood, cognition, and behavior.
Jonathan Tran +4 more
doaj +1 more source
Reactivations after 5-methoxy-N,N-dimethyltryptamine use in naturalistic settings: An initial exploratory analysis of the phenomenon’s predictors and its emotional valence [PDF]
, 2022 Ana María Ortiz Bernal +3 more
openalex +1 more source
Pharmacological MRI: Utility in Understanding Drug Mechanisms in Psychiatric Disorders
Journal of Magnetic Resonance Imaging, Volume 63, Issue 2, Page 346-363, February 2026.ABSTRACT Pharmacological MRI (pharmaMRI) has emerged as a powerful tool to study how psychoactive drugs affect brain function and to uncover mechanisms of drug action in psychiatric disorders. This review provides an overview of key techniques used in pharmaMRI, including BOLD‐fMRI, arterial spin labeling (ASL), and cerebral blood volume (CBV) mapping,
Christin Y. Sander +4 more
wiley +1 more source
Chemistry &Biodiversity, Volume 22, Issue 12, December 2025.Investigation of the seasonal influence of environmental factors on the production of secondary metabolites in Mimosa tenuiflora stem bark by Principal Component Analysis (PCA). ABSTRACT Mimosa tenuiflora (Willd.) Poir., known as “Jurema‐preta”, is a species of ethnobotanical relevance, used in traditional medicine.
Nathália Andrezza Carvalho de Souza +9 more
wiley +1 more source
Journal of Magnetic Resonance Imaging, Volume 62, Issue 6, Page 1782-1790, December 2025.ABSTRACT Background Ayahuasca is an Amazonian psychedelic brew that contains dimethyltryptamine (DMT) and beta carbolines. Prolonged use has shown changes in cognitive‐behavioral tasks, and in humans, there is evidence of changes in cortical thickness and an increase in neuroplasticity factors that could lead to modifications in functional neural ...
Lucas Rego Ramos +2 more
wiley +1 more source
A mood disorder episode with an onset under chronic cannabis consumption and accompanied with psychotic features immediately after N, N-Dimethyltryptamine (DMT) use: a case report [PDF]
Düşünen Adam Psikiyatri ve Nörolojik Bilimler Dergisi, 2011 , N-dimethyltryptamine (DMT) is a serotonin agonist hallucinogen, similar to lysergic acid diethylamide (LSD). Syntetic production of DMT as well as extraction from several plants of South American flora is possible.
Güliz Özgen +3 more
doaj