Results 81 to 90 of about 3,335 (217)

Health, Social and Recidivism Outcomes Among People Who Have Been Incarcerated in New South Wales, Australia: Study Protocol and Cohort Profile for the Prison Outcomes STudy (POST)

Drug and Alcohol Review, Volume 45, Issue 5, July 2026.
ABSTRACT Introduction We have been funded to examine post‐incarceration health and social outcomes for all people incarcerated in New South Wales, Australia, 2000–2022; assess treatment and services for drug dependence and serious mental illness; and project the impact of expanding intervention coverage. We will use a linked cohort, the Prison Outcomes
Louisa Degenhardt, Michael Farrell, Michael Doyle, Jack Stone, Chrianna Bharat, Matt Hickman, Marianne Martinello, Don Weatherburn, Kimberlie Dean, Joe Coyte, Christel Macdonald, Mary Ellen Harrod, Luke Grant, Gloria Larman, Peter Vickerman, Colette McGrath, Peter Thompson, Alison Churchill, Greg Dore, Thomas Santo Jr   +19 more
wiley   +1 more source

Gas Chromatographic Analysis of Dimethyltryptamine and beta-Carboline Alkaloids in Ayahuasca, an Amazonian Psychoactive Plant Beverage

, 2009
Introduction - Ayahuasca is obtained by infusing the pounded stems of Banisteriopsis caapi in combination with the leaves of Psychotria viridis. P. viridis is rich in the psychedelic indole N,N-dimethyltryptamine, whereas B.
OLIVEIRA, Carolina Dizioli Rodrigues De, PIRES, Ana Paula Salum, YONAMINE, Mauricio, DOERR, Felipe Augusto, MOURA, Sidnei, SILVA, Wagner Abreu E.   +5 more
core   +1 more source

Short-term safety and tolerability profile of 5-methoxy-N,N-dimethyltryptamine in human subjects: a systematic review of clinical trials

Frontiers in Psychiatry
IntroductionPsychedelic agents have regained the attention of pharmaceutical companies as promising treatments for depressive episodes. 5-Methoxy-N,N-dimethyltryptamine (5-MeO-DMT), an atypical psychedelic, is emerging as a potentially effective, novel ...
Aleksander Kwaśny, Alina Wilkowska, Wiesław Jerzy Cubała   +2 more
doaj   +1 more source

Personalised Perception: The Effect of Personality on the Sensory Effects of Psychedelics

Drug and Alcohol Review, Volume 45, Issue 5, July 2026.
ABSTRACT Introduction Psychedelics induce a wide range of sensory distortions and hallucinations (henceforth ‘distortions’). Yet, little is known about factors that influence the occurrence of certain distortions. Extra‐pharmacological variables including personality traits have been found to correlate with the occurrence of different subjective ...
Alexander Boardman, Jai Whelan, Ryan D. Ward   +2 more
wiley   +1 more source

Enlightening the “Spirit Molecule”: Photomodulation of the 5‐HT(2A) Receptor by a Light‐Controllable N,N‐Dimethyltryptamine Derivative

, 2022
Classical psychedelics are a group of hallucinogens which trigger non‐ordinary states of consciousness through activation of the 5‐HT(2A) receptor (5‐HT(2A)R) in the brain.
Decker, Michael, Gerwe, Hubert, He, Feng, Stove, Christophe, Pottie, Eline   +4 more
core   +1 more source

Psychedelic Therapy and the Role of Music: A Scoping Review of Quantitative Evidence on Subjective and Objective Outcomes

Brain and Behavior, Volume 16, Issue 6, June 2026.
ABSTRACT Purpose Psychedelics have received considerable attention due to their potential in treating psychiatric disorders. The “setting” during psychedelic‐assisted therapy (PAT) is recognized as playing a central role in the experience, during which music features prominently. Although music is theorized as directing and shaping psychedelic sessions,
T. Rowe, T. Hurzeler, E. Towers, E. Louie, K. C. Morley   +4 more
wiley   +1 more source

Unveiling the Power of Deuterium in Drug Discovery: A Comprehensive Overview

MedComm, Volume 7, Issue 6, June 2026.
The role of deuterium replacement in drug discovery, its progress, opportunities, and challenges. ABSTRACT Deuterium, the heavy isotope of hydrogen, has unfolded as a cornerstone in modern drug discovery due to its potential to influence metabolic stability and pharmacokinetic behavior.
Mukta Lele, Ajit Manchare, Swapnali Parit, Amol D. Gholap, Krishna Jadhav, Navnath Hatvate, Keshav Raj Paudel, Satish Rojekar   +7 more
wiley   +1 more source

N, N-dimethyltryptamine forms oxygenated metabolites via CYP2D6 - an in vitro investigation

, 2023
N, N-dimethyltryptamine (DMT) is a psychedelic compound that has shown potential in the treatment of depression. Aside from the primary role of monoamine oxidase A (MAO-A) in DMT metabolism, the metabolic pathways are poorly understood.
Alicia Macan-Schönleben (17344598), Emma Eckernäs (17299396), Sofia Birgersson (17344604), Kurt-Jürgen Hoffmann (17344607), Moa Andresen-Bergström (17344601), Michael Ashton (1400944)   +5 more
core   +1 more source

Integrating the Mystical Experience Questionnaire Into a Broader Psychometric Framework: English Validation of the Psychedelic Experience Scale and Comparison of Psilocybin and LSD Sessions Across Two Controlled Settings

International Journal of Methods in Psychiatric Research, Volume 35, Issue 2, June 2026.
ABSTRACT Objectives For English, the validated part of Psychedelic Experience Scale (PES48) is a four‐factor structure called the Mystical Experience Questionnaire (MEQ30). The other validated part of the PES48 consists of four more factors: two more mystical factors (paradoxicality and connectedness, which together with the MEQ30 form the MEQ40), and ...
Kurt Stocker, Matthias Hartmann, Frederick S. Barrett, William A. Richards, Nathan D. Sepeda, Laura Ley, Anna M. Becker, Friederike Holze, Matthias E. Liechti   +8 more
wiley   +1 more source

Analytically Confirmed Opioid Detections From the Emerging Drugs Network of Australia

Emergency Medicine Australasia, Volume 38, Issue 3, June 2026.
ABSTRACT Objective We describe analytically confirmed opioid‐related presentations to emergency departments (EDs) in Australia. Methods Presentations with analytically confirmed opioid exposure, between January 2021 and December 2024, were identified from the Emerging Drugs Network of Australia (EDNA) Clinical Registry.
J. Soderstrom, C. Weber, S. Greene, K. Isoardi, S. Alfred, V. Tran, P. Stockham, J. Schumann, A. Thompson, D. Fatovich, on behalf of the EDNA Investigators, Jessamine Soderstrom, Jennifer Smith, Daniel Fatovich, Shaun Greene, Sam Alfred, Katherine Isoardi, Andrew Dawson, Anthony Tzannes, Hugh Mitenko, Hwee Min Lee, Kirsty Skinner, Viet Tran, Ben Weber, Vanessa Shaw, Timothy Cook, Courtney Weber, Sharon Waterson, David McCutcheon, Natalie MacCormick, Keith Harris, Francois Oosthuizen, Peter Stockham, Dimitri Gerostamoulos, Andis Graudins, Una Nic Ionmhain, Christopher Reid, Paul Dessauer, Andrew Kozman, Mohan Raghavan, Ellie Kotkis, Craig Gardner, Giles Barrington, Jason White, Samantha Carey, Jennifer Schumann, Eden Smyth, Owen McWilliam, Jolanda Nijmeijer, Elyssia Bourke, Craig Cumming, Thanjira Jiranantakan, Abigail Stafslien‐Dumale, Maurizio Stefani   +53 more
wiley   +1 more source